LMPD Database

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LMP007498

UniProt Annotations

Entry Information
Gene NameTgl1p
Protein EntryTGL1_YEAST
UniProt IDP34163
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic ActivityA steryl ester + H(2)O = a sterol + a fatty acid.
FunctionMediates the hydrolysis of steryl esters. Required for mobilization of steryl ester, thereby playing a central role in lipid metabolism. May have weak lipase activity toward triglycerides upon some conditions, however, the relevance of such activity is unclear in vivo. {ECO:0000269|PubMed:10515935, ECO:0000269|PubMed:14640980, ECO:0000269|PubMed:15713625, ECO:0000269|PubMed:15922657}.
MiscellaneousPresent with 1470 molecules/cell in log phase SD medium
MiscellaneousPresent with 1470 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
PtmNot N-glycosylated.
SimilarityBelongs to the AB hydrolase superfamily
SimilarityBelongs to the AB hydrolase superfamily. {ECO:0000305}.
Subcellular LocationMembrane; Single-pass type III membrane protein. Lipid droplet.