LMPD Database

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LMP007523

UniProt Annotations

Entry Information
Gene NamePfa4p
Protein EntryPFA4_YEAST
UniProt IDQ12006
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic ActivityPalmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.
DomainThe DHHC domain is required for palmitoyltransferase activity. {ECO:0000250}.
FunctionCan palmitoylate RAS2 in vitro. {ECO:0000269|PubMed:12379641}.
PtmAutopalmitoylated.
SimilarityBelongs to the DHHC palmitoyltransferase family. PFA4 subfamily. {ECO:0000305}.
SimilarityContains 1 DHHC-type zinc finger. {ECO:0000255|PROSITE-ProRule:PRU00067}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000269|PubMed:15973437}; Multi-pass membrane protein {ECO:0000269|PubMed:15973437}.