LMPD Database

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LMP007527

UniProt Annotations

Entry Information
Gene NameSpo1p
Protein EntrySPO1_YEAST
UniProt IDP53541
SpeciesYeast (S288c)
Comments
Comment typeDescription
FunctionRegulates spindle pole duplication in meiosis I, but not in mitosis. Required for meiosis I, meiosis II chromosome segregation and spore formation. Binds phosphatidylinositol (4)P mono- and polyphosphates. {ECO:0000269|PubMed:10855497, ECO:0000269|PubMed:17179081}.
InductionInduced early in sporulation. Not detected during vegetative growth
InductionInduced early in sporulation. Not detected during vegetative growth. {ECO:0000269|PubMed:10855497}.
PtmGlycosylated
PtmGlycosylated. {ECO:0000269|PubMed:17179081}.
Sequence CautionSequence=AAB38425.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAA95872.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Sequence CautionSequence=AAB38425.1; Type=Erroneous gene model prediction; Evidence= ; Sequence=CAA95872.1; Type=Erroneous gene model prediction; Evidence= ;
SimilarityBelongs to the lysophospholipase family
SimilarityBelongs to the lysophospholipase family. {ECO:0000305}.
SimilarityContains 1 PLA2c domain. {ECO:0000255|PROSITE- ProRule:PRU00555}.
Subcellular LocationEndoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein.
SubunitInteracts with SPO23
SubunitInteracts with SPO23. {ECO:0000269|PubMed:17179081}.