LMPD Database

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LMP007628

UniProt Annotations

Entry Information
Gene Namelipopolysaccharide export ABC transporter ATPase
Protein EntryLPTB_ECOLI
UniProt IDP0A9V1
SpeciesE. coli
Comments
Comment typeDescription
Disruption PhenotypeResults in an earlier growth arrest and onset of cell lethality. {ECO:0000269|PubMed:16765569}.
FunctionPart of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system. {ECO:0000269|PubMed:16765569, ECO:0000269|PubMed:17056748, ECO:0000269|PubMed:18424520}.
InductionTranscriptionally regulated by sigma-E factor. {ECO:0000269|PubMed:17056748}.
SimilarityBelongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family. {ECO:0000305}.
SimilarityContains 1 ABC transporter domain. {ECO:0000255|PROSITE-ProRule:PRU00434}.
Subcellular LocationCytoplasm {ECO:0000269|PubMed:16079137}. Cell inner membrane {ECO:0000269|PubMed:16079137}; Peripheral membrane protein {ECO:0000269|PubMed:16079137}; Cytoplasmic side {ECO:0000269|PubMed:16079137}.
SubunitComponent of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP- binding proteins (LptB) and two transmembrane proteins (LptF and LptG). {ECO:0000269|PubMed:19500581}.