LMPD Database

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LMP007640

UniProt Annotations

Entry Information
Gene NameTDP-4-oxo-6-deoxy-D-glucose transaminase
Protein EntryRFFA_ECOLI
UniProt IDP27833
SpeciesE. coli
Comments
Comment typeDescription
Biophysicochemical PropertiesKinetic parameters: KM=0.11 mM for TDP-4-keto-6-deoxy-D-glucose {ECO:0000269|PubMed:15271350}; pH dependence: Optimum pH is 7.5. {ECO:0000269|PubMed:15271350}; Temperature dependence: Optimum temperature is 37 degrees Celsius. {ECO:0000269|PubMed:15271350};
Catalytic ActivitydTDP-4-amino-4,6-dideoxy-alpha-D-galactose + 2-oxoglutarate = dTDP-4-dehydro-6-deoxy-alpha-D-galactose + L- glutamate. {ECO:0000269|PubMed:15271350}.
CofactorName=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326; Evidence={ECO:0000305};
FunctionSugar aminotransferase involved in enterobacterial common antigen (ECA) elongation. {ECO:0000269|PubMed:15271350}.
PathwayBacterial outer membrane biogenesis; LPS O-antigen biosynthesis.
SimilarityBelongs to the DegT/DnrJ/EryC1 family. {ECO:0000305}.