LMPD Database

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LMP007766

UniProt Annotations

Entry Information
Gene Name3-(3-hydroxyphenyl)propionate hydroxylase
Protein EntryMHPA_ECOLI
UniProt IDP77397
SpeciesE. coli
Comments
Comment typeDescription
Catalytic Activity(2E)-3-(3-hydroxyphenyl)prop-2-enoate + NADH + O(2) = (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + H(2)O + NAD(+).
Catalytic Activity3-(3-hydroxyphenyl)propanoate + NADH + O(2) = 3-(2,3-dihydroxyphenyl)propanoate + H(2)O + NAD(+).
CofactorName=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000250};
FunctionCatalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3- hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI). {ECO:0000269|PubMed:9603882}.
PathwayAromatic compound metabolism; 3-phenylpropanoate degradation.
SimilarityBelongs to the PheA/TfdB FAD monooxygenase family. {ECO:0000305}.