LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP007800

UniProt Annotations

Entry Information
Gene NameProtein ASM-1
Protein EntryQ10916_CAEEL
UniProt IDQ10916
SpeciesC. elegans
Comments
Comment typeDescription
Catalytic ActivitySphingomyelin + H(2)O = N-acylsphingosine + phosphocholine.
Developmental StagePreferentially expressed in embryos, lower expression in later development.
FunctionConverts sphingomyelin to ceramide.
MiscellaneousDoes not require zinc ions as a cofactor.
MiscellaneousThere are two types of sphingomyelinases: asm (acid), and nsm (neutral). Only acid sphingomyelinase has been found in worms. {ECO:0000250|UniProtKB:P17405, ECO:0000269|PubMed:9603947}.
PathwayLipid metabolism; sphingolipid metabolism.
SimilarityBelongs to the acid sphingomyelinase family.
SimilarityContains 1 saposin B-type domain.
Subcellular LocationSecreted .