LMPD Database

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LMP009698

UniProt Annotations

Entry Information
Gene Name3-ketoacyl-CoA synthase 2
Protein EntryKCS17_ARATH
UniProt IDQ5XEP9
SpeciesArabidopsis
Comments
Comment typeDescription
Catalytic ActivityA very-long-chain acyl-CoA + malonyl-CoA = CoA + a very-long-chain 3-oxoacyl-CoA + CO(2).
CautionIt is uncertain whether Met-1 or Met-11 is the initiator. {ECO:0000305}.
Enzyme RegulationInhibited by K3 herbicides such as allidochlor, anilofos, cafenstrole and flufenacet. {ECO:0000269|PubMed:15277688}.
FunctionMediates the synthesis of VLCFAs from 22 to 26 carbons in length (e.g. C22, C24, C26). {ECO:0000269|PubMed:15277688}.
InductionRepressed by herbicides such as flufenacet and benfuresate. {ECO:0000269|PubMed:12916765}.
PathwayLipid metabolism; fatty acid biosynthesis.
Sequence CautionSequence=BAD95022.1; Type=Erroneous initiation; Evidence={ECO:0000305};
SimilarityBelongs to the chalcone/stilbene synthases family. {ECO:0000305}.
SimilarityContains 1 FAE (fatty acid elongase) domain. {ECO:0000305}.
Subcellular LocationMembrane {ECO:0000269|PubMed:15277688}; Multi-pass membrane protein {ECO:0000269|PubMed:15277688}.