LMPD Database

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LMP009747

UniProt Annotations

Entry Information
Gene NameABC transporter G family member 40
Protein EntryAB40G_ARATH
UniProt IDQ9M9E1
SpeciesArabidopsis
Comments
Comment typeDescription
FunctionMay be a general defense protein (By similarity). Functions as a pump to exclude Pb(2+) ions and/or Pb(2+)- containing toxic compounds from the cytoplasm. Contributes to Pb(2+) ions resistance. Confers some resistance to the terpene sclareol. {ECO:0000250, ECO:0000269|PubMed:14526118, ECO:0000269|PubMed:15923333}.
InductionCircadian-regulation. Expression increase during the dark phase and decrease during the light phase. Induced by cycloheximide (CHX), sclareol, and heavy metals such as Pb(2+) ions. ETR1-, EIN2-, JAR1-, NPR1- and EDS5-dependent induction by incompatible fungal pathogens (A.brassicicola), by compatible fungal pathogens (S.sclerotiorum and F.oxysporum), and by compatible bacterial pathogens (P.syringae pv tomato). Also induced by phytohormones such as salicylic acid (SA), methyl jasmonate (MeJA) and ethylene. {ECO:0000269|PubMed:12430018, ECO:0000269|PubMed:14526118, ECO:0000269|PubMed:15923333}.
SimilarityBelongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily. {ECO:0000305}.
SimilarityContains 2 ABC transmembrane type-2 domains. {ECO:0000305}.
SimilarityContains 2 ABC transporter domains. {ECO:0000255|PROSITE-ProRule:PRU00434}.
Subcellular LocationCell membrane {ECO:0000269|PubMed:15923333}; Multi-pass membrane protein {ECO:0000269|PubMed:15923333}.
Tissue SpecificityUbiquitous with higher levels in leaves, stems and flowers. {ECO:0000269|PubMed:12430018, ECO:0000269|PubMed:14526118, ECO:0000269|PubMed:15923333}.