LMPD Database

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LMP010441

UniProt Annotations

Entry Information
Gene Nameglycylpeptide N-tetradecanoyltransferase 1
Protein EntryNMT1_ARATH
UniProt IDQ9LTR9
SpeciesArabidopsis
Comments
Comment typeDescription
Biophysicochemical PropertiesKinetic parameters: KM=3.7 uM for myristoyl-CoA, in the presence of CPK3 {ECO:0000269|PubMed:10734119}; pH dependence: Optimum pH is 7.8. Active from pH 5.5 to 8.5. {ECO:0000269|PubMed:10734119};
Catalytic ActivityTetradecanoyl-CoA + glycylpeptide = CoA + N- tetradecanoylglycylpeptide.
FunctionAdds a myristoyl group to the N-terminal glycine residue of certain cellular proteins. Can also use decanoyl-CoA and lauroyl-CoA as substrates. {ECO:0000269|PubMed:10734119, ECO:0000269|PubMed:12912986}.
Sequence CautionSequence=BAA97032.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
SimilarityBelongs to the NMT family. {ECO:0000305}.
Subcellular LocationCytoplasm {ECO:0000269|PubMed:10734119}. Note=Mostly associated to ribosomes. Present to a lower extent in mitochondria.
Tissue SpecificityExpressed ubiquitously, with higher levels in young tissues (at protein level). {ECO:0000269|PubMed:10734119}.