LMPD Database

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LMP010524

UniProt Annotations

Entry Information
Gene NameLAG1 longevity assurance-like 2
Protein EntryLAG12_ARATH
UniProt IDQ9LJK3
SpeciesArabidopsis
Comments
Comment typeDescription
FunctionMediates resistance to sphinganine-analog mycotoxins (SAMs) by restoring the sphingolipid biosynthesis. Could salvage the transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi apparatus in ceramides-depleted cells after SAM exposure (By similarity). {ECO:0000250}.
SimilarityContains 1 TLC (TRAM/LAG1/CLN8) domain. {ECO:0000255|PROSITE-ProRule:PRU00205}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.