LMPD Database

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LMP011144

UniProt Annotations

Entry Information
Gene NameS-acyltransferase 10
Protein EntryZDH11_ARATH
UniProt IDQ7XA86
SpeciesArabidopsis
Comments
Comment typeDescription
Catalytic ActivityPalmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.
Developmental StageExpressd in tapetal layer of developing anthers and then expression gradually increases in developing microspores and in mature pollen. {ECO:0000269|PubMed:23482856}.
Disruption PhenotypePleiotropic growth defects, including smaller leaves, dwarfism, and sterility. Hypersensitivity to salt stress and compromised pollen tube growth. {ECO:0000269|PubMed:23482856}.
DomainThe DHHC domain is required for palmitoyltransferase activity. {ECO:0000250}.
FunctionS-acyltransferase involved in protein lipid modification. Catalyzes the palmitoylation of proteins peripheral or integral to the tonoplast. Required for the tonoplast localization of CBL2, CBL3 and CBL6, but not for the plasma membrane localization of CBL9, for the endosome localization of RABF1 or for the endomembrane localization of RABF2B. {ECO:0000269|PubMed:22968831, ECO:0000269|PubMed:23482856, ECO:0000269|Ref.5}.
InductionNot regulated by salt stresses. {ECO:0000269|PubMed:23482856}.
Sequence CautionSequence=CAB63003.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
SimilarityBelongs to the DHHC palmitoyltransferase family. {ECO:0000305}.
SimilarityContains 1 DHHC-type zinc finger. {ECO:0000255|PROSITE-ProRule:PRU00067}.
Subcellular LocationVacuole membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Note=Transient expression results in mistargeting of PAT10 to the Golgi apparatus, while the non- functional mutant is also localized in Golgi apparatus membranes. {ECO:0000269|PubMed:22968831, ECO:0000269|PubMed:23482856}.
Tissue SpecificityExpressed in mature embryos, embryo sacs, cotyledons, whole seedlings, hydathodes, guard cells, sites of lateral root initiation, root tips and phloem, but not in xylem. {ECO:0000269|PubMed:23482856}.