LMPD Database

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LMP011274

Record overview

LMPD IDLMP011274
Gene ID816258
SpeciesArabidopsis thaliana (Arabidopsis)
Gene Nameserine/threonine-protein kinase/endoribonuclease IRE1a
Gene SymbolIRE1A
SynonymsARABIDOPSIS THALIANA INOSITOL REQUIRING 1-2; ATIRE1-2; INOSITOL REQUIRING 1-2; IRE1-2; IRE1A; MJB20.8; MJB20_8; TRANSMEMBRANE PROTEIN KINASE/RIBONUCLEASE
Alternate namesserine/threonine-protein kinase/endoribonuclease IRE1a
Chromosome2
EC Number2.7.11.1
SummaryEncodes a endoribonuclease/protein kinase IRE1-like protein that is predicted to form a type I transmembrane protein structure and contain kinase/endoribonuclease domains at their C-terminal halves. The transcript levels for several ER-stress responsive genes, including six protein disulfide isomerases (PDIs), BiP2, and AtbZIP60 are not affected in ire1-2 null mutants.
OrthologsView orthologs and multiple alignments for IRE1A

Proteins

serine/threonine-protein kinase/endoribonuclease IRE1a
Refseq ID:NP_565419
Protein GI:18398454
UniProt ID:Q9C5S2
mRNA ID:NM_127306
Length:841
RefSeq Status:REVIEWED
MPPRCPFLRHLFFLLLLLSPWIMSPCGGAADDVTYPIVPSSPGRRSILQIRREPPTEPNTKLVVDRDGKVFLKQQPKETPYWSFSTGSPMHSLYQAPANN
NTENATEITRPHIIVEYLNNSKAATTVDGYHNWTVQEFFRQKPLVTDDGVTLGSETTSAYLVDGRSGRLIHVYKSTGDTKITNALVKPASTEDFVNEPLL
IRRTDSKLEHFSKTTGKLVWNLTVSHFRAALLCDPVFNSGYDLGPKLQTGIYMPLLCGSQIDVRGPEIVIRVLHDQPMNVKMLPSPSLNHFESENSIMPF
GKARESRKLQEQHKQKYTYLFGQWSPVKLLAPLVLLGVVVSVFIKKFSSRGSDVSLKAGPSKKKKNRKSAKDTNRQSVPRGQDQFELIEGGQMLLGFNNF
QSGATDGRKIGKLFLSSKEIAKGSNGTVVFEGIYEGRPVAVKRLVRSHHEVAFKEIQNLIASDQHTNIIRWYGVEYDQDFVYLSLERCTCSLDDLIKSYL
EFSMTKVLENNDSTEGVAAYKIQLDSLEGVIKGNNFWKVGGHPSPLMLKLMRDIVCGIVHLHELGIVHRDLKPQNVLISKDMTLSAKLSDMGISKRMSRD
MSSLGHLATGSGSSGWQAPEQLLQGRQTRAVDMFSLGCVIFYTITGCKHPFGDDLERDVNIVKNKVDLFLVEHVPEASDLISRLLNPDPDLRPSATEVLL
HPMFWNSEMRLSFLRDASDRVELENREADSEILKAMESTAPVAIGGKWDEKLEPVFITNIGRYRRYKYDSIRDLLRVIRNKLNHHRELPPEIQELVGTVP
EGFDEYFAVRFPKLLIEVYRVISLHCREEEVFRKYFKCDII