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LMPD Database

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LMP011545

UniProt Annotations

Entry Information

Gene Name	prominin 1a
Protein Entry	PRM1A_DANRE
UniProt ID	Q9W735
Species	Zebrafish

Comments

Comment type	Description
Function	May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. Involved in regulation of MAPK and Akt signaling pathways (By similarity). {ECO:0000250}.
Similarity	Belongs to the prominin family. {ECO:0000305}.
Subcellular Location	Apical cell membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}. Cell projection, microvillus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}. Endoplasmic reticulum-Golgi intermediate compartment {ECO:0000250}.