LMPD Database

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LMP011667

UniProt Annotations

Entry Information
Gene Nameprotein tyrosine phosphatase-like A domain containing 1
Protein EntryHADC_DANRE
UniProt IDQ7SY06
SpeciesZebrafish
Comments
Comment typeDescription
Catalytic ActivityA very-long-chain (3R)-3-hydroxyacyl-CoA = a very-long-chain trans-2,3-dehydroacyl-CoA + H(2)O.
FunctionResponsible for the dehydration step in very long-chain fatty acid (VLCFA) synthesis. Involved in Rac1-signaling pathways leading to the modulation of gene expression (By similarity). {ECO:0000250}.
SimilarityBelongs to the very long-chain fatty acids dehydratase HACD family. {ECO:0000305}.
SimilarityContains 1 CS domain. {ECO:0000255|PROSITE- ProRule:PRU00547}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.