LMPD Database

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LMP012475

Gene Information

Entrez Gene ID25146
Gene Namecytochrome P450, family 17, subfamily a, polypeptide 1
Gene SymbolCyp17a1
SpeciesRattus norvegicus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0030424 IEA:EnsemblCaxon
GO:0042995 IDA:RGDCcell projection
GO:0005783 IDA:RGDCendoplasmic reticulum
GO:0043231 IDA:RGDCintracellular membrane-bounded organelle
GO:0016020 IEA:UniProtKB-KWCmembrane
GO:0005739 IEA:EnsemblCmitochondrion
GO:0043025 IDA:RGDCneuronal cell body
GO:0047442 IEA:UniProtKB-ECF17-alpha-hydroxyprogesterone aldolase activity
GO:0020037 ISS:UniProtKBFheme binding
GO:0005506 IEA:InterProFiron ion binding
GO:0004508 IDA:RGDFsteroid 17-alpha-monooxygenase activity
GO:0030325 IEP:RGDPadrenal gland development
GO:0006702 TAS:RGDPandrogen biosynthetic process
GO:0018879 IEP:RGDPbiphenyl metabolic process
GO:0071236 IEP:RGDPcellular response to antibiotic
GO:0071371 IEP:RGDPcellular response to gonadotropin stimulus
GO:0071222 IEP:RGDPcellular response to lipopolysaccharide
GO:0018894 IEP:RGDPdibenzo-p-dioxin metabolic process
GO:0006704 IEA:EnsemblPglucocorticoid biosynthetic process
GO:0021766 IEP:RGDPhippocampus development
GO:0042446 ISS:UniProtKBPhormone biosynthetic process
GO:0033327 IEP:RGDPLeydig cell differentiation
GO:0008584 IEP:RGDPmale gonad development
GO:0006082 IEP:RGDPorganic acid metabolic process
GO:0030728 IEP:RGDPovulation
GO:0018958 IEP:RGDPphenol-containing compound metabolic process
GO:0018963 IEP:RGDPphthalate metabolic process
GO:0090031 IMP:RGDPpositive regulation of steroid hormone biosynthetic process
GO:0042448 ISS:UniProtKBPprogesterone metabolic process
GO:0010034 IEP:RGDPresponse to acetate
GO:0051591 IEP:RGDPresponse to cAMP
GO:0034097 IEP:RGDPresponse to cytokine
GO:0042493 IEP:RGDPresponse to drug
GO:0060992 IEP:RGDPresponse to fungicide
GO:0034698 IEP:RGDPresponse to gonadotropin
GO:0009635 IEP:RGDPresponse to herbicide
GO:0017085 IEP:RGDPresponse to insecticide
GO:0010212 IEP:RGDPresponse to ionizing radiation
GO:0051597 IEP:RGDPresponse to methylmercury
GO:0031667 IEP:RGDPresponse to nutrient levels
GO:0014070 IEP:RGDPresponse to organic cyclic compound
GO:0010033 IEP:RGDPresponse to organic substance
GO:0032526 IEP:RGDPresponse to retinoic acid
GO:0048545 IEP:RGDPresponse to steroid hormone
GO:0009636 IEP:RGDPresponse to toxic substance
GO:0006694 IMP:RGDPsteroid biosynthetic process
GO:0008202 ISS:UniProtKBPsteroid metabolic process
KEGG Pathway Links
KEGG Pathway IDDescription
M00110C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
M00109C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
rno01100Metabolic pathways
ko04913Ovarian steroidogenesis
rno04913Ovarian steroidogenesis
ko04917Prolactin signaling pathway
rno04917Prolactin signaling pathway
ko00140Steroid hormone biosynthesis
rno00140Steroid hormone biosynthesis
REACTOME Pathway Links
REACTOME Pathway IDDescription
5953941Androgen biosynthesis
5953258Biological oxidations
5953485Cytochrome P450 - arranged by substrate type
5953932Endogenous sterols
5953942Glucocorticoid biosynthesis
5953250Metabolism
5953289Metabolism of lipids and lipoproteins
5953937Metabolism of steroid hormones and vitamin D
5953326Phase 1 - Functionalization of compounds