LMPD Database

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LMP012785

Record overview

LMPD IDLMP012785
Gene ID83537
SpeciesMacaca mulata (Rhesus monkey)
Gene Namesphingomyelin phosphodiesterase 2, neutral membrane
Gene SymbolSmpd2
SynonymsnSMase;
Alternate namessphingomyelin phosphodiesterase 2; N-SMase; lyso-PAF-PLC; neutral sphingomyelinase; lyso-platelet-activating factor-phospholipase C;
Chromosome20
Map Location20q12
EC Number3.1.4.12
Summarycatalyzes the Mg2+ dependent hydrolysis of sphingomyelin to form N-acylsphingosine and choline phosphate; also has a lower activity for the hydrolysis of lyso-platelet activating factor to 1-alkylglycerol [RGD, Feb 2006]
OrthologsView orthologs and multiple alignments for Smpd2

Proteins

sphingomyelin phosphodiesterase 2
Refseq ID:NP_112650
Protein GI:14389301
UniProt ID:Q9ET64
mRNA ID:NM_031360
Length:422
RefSeq Status:
MKHNFSLRLRVFNLNCWDIPYLSKHRADRMKRLGDFLNLESFDLALLEEVWSEQDFQYLKQKLSLTYPDAHYFRSGIIGSGLCVFSRHPIQEIVQHVYTL
NGYPYKFYHGDWFCGKAVGLLVLHLSGLVLNAYVTHLHAEYSRQKDIYFAHRVAQAWELAQFIHHTSKKANVVLLCGDLNMHPKDLGCCLLKEWTGLRDA
FVETEDFKGSEDGCTMVPKNCYVSQQDLGPFPFGVRIDYVLYKAVSGFHICCKTLKTTTGCDPHNGTPFSDHEALMATLCVKHSPPQEDPCSAHGSAERS
ALISALREARTELGRGIAQARWWAALFGYVMILGLSLLVLLCVLAAGEEAREVAIMLWTPSVGLVLGAGAVYLFHKQEAKSLCRAQAEIQHVLTRTTETQ
DLGSEPHPTHCRQQEADRAEEK