LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP012802

UniProt Annotations

Entry Information
Gene Namesyndecan binding protein
Protein EntrySDCB1_RAT
UniProt IDQ9JI92
SpeciesRat
Comments
Comment typeDescription
FunctionSeems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway.
PtmPhosphorylated on tyrosine residues
SimilarityContains 2 PDZ (DHR) domains. {ECO:0000255|PROSITE- ProRule:PRU00143}.
Subcellular LocationMembrane ; Peripheral membrane protein {ECO:0000250}. Melanosome .
SubunitMonomer and homodimer. Interacts with neurofascin, SDBP2 and PTPRJ. Interacts with SDC1, SDC2, SDC3, SDC4, NRXN2, EPHA7, EPHB1, NF2 isoform 1, TGFA and IL5RA (By similarity)