LMPD Database

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LMP012879

UniProt Annotations

Entry Information
Gene Namealdehyde dehydrogenase 1 family, member A2
Protein EntryAL1A2_RAT
UniProt IDQ63639
SpeciesRat
Comments
Comment typeDescription
Catalytic ActivityRetinal + NAD(+) + H(2)O = retinoate + NADH.
FunctionRecognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Does metabolize octanal and decanal but does not metabolize citral, benzaldehyde, acetaldehyde and propanal efficiently.
PathwayCofactor metabolism; retinol metabolism.
Sequence CautionSequence=AAC52637.1; Type=Erroneous initiation; Evidence= ;
SimilarityBelongs to the aldehyde dehydrogenase family
Subcellular LocationCytoplasm.
SubunitHomotetramer.
Tissue SpecificityFound in testis and less abundantly in lung, brain, heart, liver and kidney.