LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP012988

UniProt Annotations

Entry Information
Gene Namealdehyde dehydrogenase 1 family, member A3
Protein EntryAL1A3_RAT
UniProt IDQ8K4D8
SpeciesRat
Comments
Comment typeDescription
Catalytic ActivityAn aldehyde + NAD(P)(+) + H(2)O = a carboxylate + NAD(P)H.
FunctionRecognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Seems to be the key enzyme in the formation of an RA gradient along the dorso-ventral axis during the early eye development and also in the development of the olfactory system (By similarity)
PathwayCofactor metabolism; retinol metabolism.
SimilarityBelongs to the aldehyde dehydrogenase family
Subcellular LocationCytoplasm .