LMPD Database

LMP013182

Gene Information

Entrez Gene ID	299858
Gene Name	low density lipoprotein receptor-related protein 1
Gene Symbol	Lrp1
Species	Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0030136	IDA:RGD	C	clathrin-coated vesicle
GO:0030425	IDA:RGD	C	dendrite
GO:0005768	IDA:RGD	C	endosome
GO:0005887	IEA:Ensembl	C	integral component of plasma membrane
GO:0005765	IEA:Ensembl	C	lysosomal membrane
GO:0043025	IDA:RGD	C	neuronal cell body
GO:0043235	IEA:Ensembl	C	receptor complex
GO:0005509	IEA:Ensembl	F	calcium ion binding
GO:0044822	IEA:Ensembl	F	poly(A) RNA binding
GO:0002020	IPI:RGD	F	protease binding
GO:0007568	IEP:RGD	P	aging
GO:0035909	IEA:Ensembl	P	aorta morphogenesis
GO:0043277	IEA:Ensembl	P	apoptotic cell clearance
GO:0097242	IEA:Ensembl	P	beta-amyloid clearance
GO:0008283	IMP:RGD	P	cell proliferation
GO:0008203	IEA:Ensembl	P	cholesterol metabolic process
GO:0042157	IEP:RGD	P	lipoprotein metabolic process
GO:0043524	IMP:RGD	P	negative regulation of neuron apoptotic process
GO:2000587	IEA:Ensembl	P	negative regulation of platelet-derived growth factor receptor-beta signaling pathway
GO:0014912	IEA:Ensembl	P	negative regulation of smooth muscle cell migration
GO:0030178	IEA:Ensembl	P	negative regulation of Wnt signaling pathway
GO:0010875	IEA:Ensembl	P	positive regulation of cholesterol efflux
GO:0051222	IMP:RGD	P	positive regulation of protein transport
GO:0007205	IMP:RGD	P	protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0006898	IMP:RGD	P	receptor-mediated endocytosis
GO:0032956	IEA:Ensembl	P	regulation of actin cytoskeleton organization
GO:0032429	IEA:Ensembl	P	regulation of phospholipase A2 activity

KEGG Pathway Links

REACTOME Pathway Links

REACTOME Pathway ID	Description
5954562	Binding and Uptake of Ligands by Scavenger Receptors
5953253	Disease
5953382	Diseases associated with visual transduction
5954392	Retinoid metabolism and transport
5954561	Scavenging of heme from plasma
5953381	Signal Transduction
5953380	Visual phototransduction