LMPD Database

LMP013192

Gene Information

Entrez Gene ID	300652
Gene Name	sortilin-related receptor, LDLR class A repeats-containing
Gene Symbol	Sorl1
Species	Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005769	IEA:Ensembl	C	early endosome
GO:0005783	IEA:Ensembl	C	endoplasmic reticulum
GO:0005615	IEA:Ensembl	C	extracellular space
GO:0070062	IEA:Ensembl	C	extracellular vesicular exosome
GO:0031985	IEA:Ensembl	C	Golgi cisterna
GO:0016021	IEA:UniProtKB-KW	C	integral component of membrane
GO:0005771	IDA:RGD	C	multivesicular body
GO:0043025	IDA:RGD	C	neuronal cell body
GO:0005641	IEA:Ensembl	C	nuclear envelope lumen
GO:0055037	IEA:Ensembl	C	recycling endosome
GO:0005802	IEA:Ensembl	C	trans-Golgi network
GO:0001540	IEA:Ensembl	F	beta-amyloid binding
GO:0030169	IEA:Ensembl	F	low-density lipoprotein particle binding
GO:0016477	IMP:RGD	P	cell migration
GO:0008283	IEP:RGD	P	cell proliferation
GO:1902960	IEA:Ensembl	P	negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
GO:1902430	IEA:Ensembl	P	negative regulation of beta-amyloid formation
GO:0043407	IEA:Ensembl	P	negative regulation of MAP kinase activity
GO:1902963	IEA:Ensembl	P	negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
GO:1902997	IEA:Ensembl	P	negative regulation of neurofibrillary tangle assembly
GO:0050768	IEA:Ensembl	P	negative regulation of neurogenesis
GO:1901215	IEA:Ensembl	P	negative regulation of neuron death
GO:0032091	IEA:Ensembl	P	negative regulation of protein binding
GO:0032460	IEA:Ensembl	P	negative regulation of protein oligomerization
GO:1902948	IEA:Ensembl	P	negative regulation of tau-protein kinase activity
GO:1902771	IEA:Ensembl	P	positive regulation of choline O-acetyltransferase activity
GO:1902955	IEA:Ensembl	P	positive regulation of early endosome to recycling endosome transport
GO:2001137	IEA:Ensembl	P	positive regulation of endocytic recycling
GO:1902953	IEA:Ensembl	P	positive regulation of ER to Golgi vesicle-mediated transport
GO:0045732	IEA:Ensembl	P	positive regulation of protein catabolic process
GO:0070863	IEA:Ensembl	P	positive regulation of protein exit from endoplasmic reticulum
GO:1902966	IEA:Ensembl	P	positive regulation of protein localization to early endosome
GO:0006892	IEA:Ensembl	P	post-Golgi vesicle-mediated transport
GO:0051604	IEA:Ensembl	P	protein maturation
GO:0045053	IEA:Ensembl	P	protein retention in Golgi apparatus
GO:0000042	IEA:Ensembl	P	protein targeting to Golgi
GO:0006622	IEA:Ensembl	P	protein targeting to lysosome
GO:0014910	IEA:Ensembl	P	regulation of smooth muscle cell migration