LMPD Database

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LMP013454

UniProt Annotations

Entry Information
Gene NameBerardinelli-Seip congenital lipodystrophy 2 (seipin)
Protein EntryBSCL2_RAT
UniProt IDQ5FVJ6
SpeciesRat
Comments
Comment typeDescription
FunctionIs a regulator of lipid catabolism essential for adipocyte differentiation. Necessary for correct lipid storage and lipid droplets maintenance; may play a tissue-autonomous role in controlling lipid storage in adipocytes and in preventing ectopic lipid droplet formation in non-adipose tissues. May also be involved in the central regulation of energy homeostasis (By similarity)
SimilarityBelongs to the seipin family
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein .