Lipidomics studies on macrophages - RAW 264.7 cells treated with Kdo2-Lipid A and compactin
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Sphingolipids
|
Details/Graph | LM_ID | Name | Kdo+Comp Kdo Comp 0.5 hrs |
Kdo+Comp Kdo Comp 1 hr |
Kdo+Comp Kdo Comp 2 hrs |
Kdo+Comp Kdo Comp 4 hrs |
Kdo+Comp Kdo Comp 8 hrs |
Kdo+Comp Kdo Comp 12 hrs |
Kdo+Comp Kdo Comp 24 hrs |
---|---|---|---|---|---|---|---|---|---|
LMSP02010001 | C14 Cer | 1.09
0.838
1
| 1.08
0.858
0.775
| 0.412
0.699
0.477
| 0.614
1
0.714
| 1.08
2.18
1.18
| 1
1.49
0.915
| 1.85
2.7
1.21
| |
LMSP02010004 | C16 Cer | 1.02
0.868
0.907
| 1.04
0.969
0.918
| 0.954
0.883
0.889
| 1.14
1
1.21
| 0.86
0.996
0.975
| 1.41
1.55
1.23
| 2.44
2.91
1.67
| |
LMSP02010006 | C18 Cer | 1.09
1.33
0.83
| 0.772
1.11
0.536
| 0.761
0.797
0.898
| 1.34
0.905
1.02
| 0.736
1.12
0.836
| 0.88
1.2
1.11
| 2.79
2.88
1.82
| |
LMSP02010003 | C18:1 Cer | 1.69
1
1.04
| 0.968
0.677
0.677
| 0.87
0.909
0.519
| 2.06
1.64
1.7
| 0.918
0.918
0.863
| 0.952
1.54
1
| 0.429
1.24
0.571
| |
LMSP02010007 | C20 Cer | 1.62
1.33
0.971
| 0.678
0.93
0.72
| 1.38
1.38
1.38
| 0.9
1.53
1.57
| 0.452
1.19
1.05
| 1.39
0.857
1.19
| 3.26
3.68
2.55
| |
LMSP02010008 | C22 Cer | 0.813
0.759
0.818
| 0.798
0.765
0.798
| 0.939
0.869
0.862
| 1.52
1.36
1.33
| 0.776
0.863
0.907
| 1.32
1.35
1.54
| 3.95
4.09
2.31
| |
LMSP02010012 | C24 Cer | 1.01
0.939
1.05
| 0.717
0.585
0.741
| 0.866
0.66
0.896
| 1.28
1.06
1.14
| 0.956
0.712
1.1
| 1.67
1.29
1.58
| 4.57
3.78
1.93
| |
LMSP02010009 | C24:1 Cer | 1.15
1.08
1.12
| 0.899
0.848
1.1
| 0.987
0.725
0.915
| 1.06
1.13
1.14
| 0.901
0.886
0.953
| 1.19
1.19
1.16
| 1.56
1.53
1.5
| |
LMSP02010011 | C26 Cer | 0.843
0.645
0.797
| 0.76
0.82
1.36
| 1.09
1.02
0.872
| 0.806
0.747
0.865
| 0.664
0.973
0.882
| 1.5
2.93
1.43
| 2.21
1.7
1.45
| |
LMSP02010010 | C26:1 Cer | 1.05
0.948
1.41
| 1.11
1
1.02
| 1.09
0.988
1.24
| 1.01
0.9
1
| 0.93
0.79
0.678
| 1.07
2.5
1.6
| 1.19
2.06
1.31
| |
LMSP03010028 | C14 Sphingomyelin | 0.998
1.13
1.01
| 1.06
1.08
1.08
| 0.924
0.908
0.894
| 1
1.09
1.02
| 0.967
1.02
0.969
| 1.25
1.26
1.13
| 1.21
0.848
1.18
| |
LMSP03010003 | C16 Sphingomyelin | 1.04
1.1
1.03
| 0.928
1.01
1.04
| 0.949
0.892
0.898
| 1.05
1.11
0.994
| 0.907
0.94
0.954
| 1.11
1.19
1.14
| 1.16
1.27
1.24
| |
LMSP03010001 | C18 Sphingomyelin | 1.09
1.17
1.08
| 0.868
0.907
0.946
| 0.878
0.827
0.841
| 1.09
1.25
1.05
| 0.934
0.979
0.915
| 1.08
1.14
1.16
| 1.17
1.22
1.21
| |
LMSP03010029 | C18:1 Sphingomyelin | 1.16
1.09
1.12
| 0.896
0.971
1.02
| 0.964
0.799
0.822
| 0.935
1.08
0.862
| 1.04
1.1
0.954
| 1.21
1.27
1.2
| 1.03
0.915
1.07
| |
LMSP03010005 | C20 Sphingomyelin | 1.14
1.26
1.06
| 0.838
0.898
0.931
| 0.933
0.895
0.863
| 1.24
1.33
1.08
| 0.841
0.96
0.965
| 0.967
1.13
1.07
| 1.13
1.29
1.23
| |
LMSP03010006 | C22 Sphingomyelin | 1.18
1.34
1.11
| 0.82
0.856
0.907
| 0.97
0.886
0.94
| 1.22
1.35
1.11
| 0.786
0.938
0.924
| 1
1.07
1.1
| 1.1
1.28
1.25
| |
LMSP03010008 | C24 Sphingomyelin | 1.26
1.45
1.14
| 0.761
0.809
0.851
| 0.968
0.818
0.882
| 1.26
1.37
1.13
| 0.789
0.911
0.954
| 0.98
1.07
1.12
| 0.99
1.18
1.2
| |
LMSP03010007 | C24:1 Sphingomyelin | 1.1
1.23
1.11
| 0.834
0.905
0.959
| 1.01
0.837
0.901
| 1.12
1.25
1.01
| 0.831
0.847
0.945
| 0.98
1.01
1.15
| 0.737
0.802
1.12
| |
LMSP03010010 | C26 Sphingomyelin | 1.22
1.29
1.21
| 0.791
0.847
0.856
| 1.06
0.95
1.06
| 1.24
1.53
1.25
| 0.742
1.15
1.15
| 1.03
1.13
1.08
| 0.736
1.02
1.12
| |
LMSP03010009 | C26:1 Sphingomyelin | 1.15
1.3
1.21
| 0.753
0.829
0.854
| 1.05
0.887
0.965
| 1.4
1.43
1.11
| 0.792
0.856
0.984
| 0.928
1.02
1.1
| 0.679
0.733
0.948
| |
LMSP0501AA26 | C14 GlcCer | 0.964
1.39
1.33
| 0.898
0.419
0.808
| 1
0.287
0.496
| 0.374
0.435
0.957
| -
-
-
| 3.75
2.75
3.35
| 0.825
1.63
0.875
| |
LMSP0501AA03 | C16 GlcCer | 0.976
0.904
0.979
| 0.849
1
0.953
| 1.17
1.14
0.934
| 1.07
0.972
0.899
| 0.936
1.31
1.1
| 1.14
1.32
0.935
| 1.62
2.69
1.49
| |
LMSP0501AA05 | C18 GlcCer | 0.892
1.97
1.51
| 0.607
0.714
2.29
| 1.85
1.87
0.7
| 0.762
1.21
0.733
| 0.813
0.838
1.29
| 1.27
1.73
1.45
| 3.43
2.37
2
| |
LMSP0501AA27 | C18:1 GlcCer | -
-
-
| -
-
-
| -
-
-
| -
-
-
| -
-
-
| -
-
-
| -
-
-
| |
LMSP0501AA06 | C20 GlcCer | 1.88
1.32
1.71
| 0.987
1.1
1.1
| 0.897
0.619
1.04
| 1.06
1.1
0.868
| 1.01
1.28
0.592
| 1.68
3.16
1.33
| 1.02
1.64
1.1
| |
LMSP0501AA07 | C22 GlcCer | 1.01
1.46
1.23
| 0.642
0.493
0.633
| 1.32
1.1
1.31
| 1.28
1.29
1.32
| 0.989
1.36
0.995
| 1.17
1.32
1.81
| 2.11
3.19
1.45
| |
LMSP0501AA09 | C24 GlcCer | 1.15
1.48
1.14
| 0.892
0.761
1.16
| 1.39
1.04
1.01
| 0.936
1.01
0.7
| 0.824
0.986
0.616
| 0.853
1.33
1.21
| 2.48
3.31
1.58
| |
LMSP0501AA08 | C24:1 GlcCer | 1.08
1.32
1.03
| 0.677
0.703
0.954
| 1.53
1.11
1.03
| 0.825
0.865
0.889
| 0.76
0.495
0.958
| 0.661
0.91
1.35
| 0.947
1.28
1.52
| |
LMSP0501AA11 | C26 GlcCer | 1.21
1.16
0.688
| 2.18
1.64
1.09
| 2.6
1.2
2.2
| 1.49
1.18
0.692
| 1.2
1.5
1.8
| 1.5
5
2.5
| 0.611
0.833
0.556
| |
LMSP0501AA10 | C26:1 GlcCer | 2.06
3.44
1.44
| 4.19
3.21
1.58
| 1.51
0.776
1.06
| 1.54
2.18
2.34
| 1.17
1.44
0.862
| 1.12
3.97
1.33
| 2.93
1.85
1.87
| |
LMSP05010030 | C14DH Cer | 0.27
1.01
0.261
| 1.35
1.24
0.941
| 3.15
1.96
1.39
| 1.49
1.05
1.24
| 0.98
1.85
0.699
| 1.07
1.78
0.981
| 0.622
1.68
0.535
| |
LMSP02020001 | C16DH Cer | 1.23
1.6
1.34
| 1
1.05
1.12
| 0.881
0.735
0.908
| 0.937
1.05
1.02
| 0.992
1.1
0.953
| 1.5
1.78
1.31
| 1.28
2.05
1.21
| |
LMSP02020015 | C18:1DH Cer | 0.787
1.95
1.47
| 1.25
0.989
3.12
| 1.81
1.12
1.3
| 1.27
2.46
1.59
| 1.12
0.618
0.859
| 1.26
0.969
1.31
| 0.422
0.813
0.639
| |
LMSP02020008 | C18DH Cer | 1.59
1.88
0.933
| 0.716
0.621
1.05
| 1.46
0.763
1.08
| 0.691
1.02
0.722
| 1.05
0.811
0.594
| 1.73
2.12
1.54
| 0.844
1.85
1.18
| |
LMSP02020009 | C20DH Cer | 0.67
0.675
0.325
| 0.526
0.437
0.186
| 0.944
1.85
0.631
| 0.334
0.763
0.526
| 1.87
0.911
1.06
| 1.37
1.23
0.578
| 1.5
2.02
1.06
| |
LMSP02020010 | C22DH Cer | 1.1
0.932
0.91
| 0.589
0.942
0.926
| 1.14
0.686
0.728
| 1.7
1.33
1.57
| 0.991
1.28
1.24
| 2.2
1.57
1.12
| 1.88
3.49
1.18
| |
LMSP02020011 | C24:1DH Cer | 1.22
1.31
0.966
| 1.32
0.96
0.925
| 0.934
0.533
0.665
| 0.861
1.13
0.75
| 0.818
0.836
0.64
| 1.1
0.947
1.1
| 1.47
1.93
1.4
| |
LMSP02020012 | C24DH Cer | 0.619
0.659
0.557
| 1.21
0.933
0.77
| 0.804
0.886
0.88
| 1.11
1.23
0.897
| 1.21
1.16
0.826
| 1.87
1.67
1.31
| 3.06
3.61
1.06
| |
LMSP02020013 | C26:1DH Cer | 0.7
6
2.2
| 1.69
1.99
0.714
| 1.47
1.2
0.467
| 0.739
0.665
0.754
| 1.82
2.34
0.374
| 0.95
0.736
1.12
| 2.43
2.26
1.12
| |
LMSP02020014 | C26DH Cer | 2.17
1.08
2.83
| 1.15
2.46
0.5
| 1.97
0.606
0.472
| 1.48
0.75
2.28
| 1.81
1.11
0.381
| 1.4
3.94
1
| 2.13
3.54
1
| |
LMSP03010030 | C14DH Sphingomyelin | 1
1.07
1.03
| 0.936
1.14
1.04
| 0.946
0.977
0.943
| 1.13
1.12
1.07
| 0.995
1.08
0.97
| 1.04
1.27
1.15
| 1.3
1.27
1.23
| |
LMSP03010004 | C16DH Sphingomyelin | 1.06
1.08
0.998
| 0.828
0.93
0.943
| 0.96
0.902
0.927
| 1.16
1.09
1.02
| 0.931
0.966
1.02
| 1.08
1.11
1.14
| 1.19
1.28
1.26
| |
LMSP03010031 | C18:1DH Sphingomyelin | 1.1
1.12
1.16
| 0.839
0.901
0.945
| 0.908
0.905
0.873
| 1.12
1.22
1.06
| 0.934
0.99
1.04
| 1.06
1.14
1.22
| 1.08
1.24
1.23
| |
LMSP03010020 | C18DH Sphingomyelin | 0.997
1.06
0.983
| 0.87
0.835
0.937
| 0.912
0.912
0.988
| 1.26
1.29
1.14
| 0.857
0.906
0.966
| 1.1
1.12
1.18
| 1.3
1.44
1.36
| |
LMSP03010021 | C20DH Sphingomyelin | 1.08
1.18
1.15
| 0.667
0.85
0.93
| 1.07
0.946
0.969
| 1.34
1.24
1.08
| 0.743
0.978
0.947
| 0.938
1.18
1.18
| 1.31
1.41
1.39
| |
LMSP03010022 | C22DH Sphingomyelin | 1.3
1.36
1.08
| 0.785
0.883
0.839
| 0.863
0.822
0.888
| 1.3
1.35
1.22
| 0.732
0.907
1.04
| 0.994
1.12
1.19
| 1.22
1.39
1.58
| |
LMSP03010023 | C24:1DH Sphingomyelin | 1.3
1.4
1.2
| 0.755
0.846
0.858
| 0.921
0.911
0.962
| 1.22
1.21
1.12
| 0.744
0.856
0.962
| 0.947
1.04
1.15
| 0.92
1.16
1.28
| |
LMSP03010024 | C24DH Sphingomyelin | 1.47
1.54
1.4
| 0.69
0.734
0.807
| 0.797
0.814
0.878
| 1.34
1.26
1.17
| 0.621
0.755
0.898
| 0.952
1.09
1.24
| 1.08
1.25
1.47
| |
LMSP03010025 | C26:1DH Sphingomyelin | 1.29
1.1
0.937
| 0.981
0.798
0.899
| 0.826
0.763
0.661
| 1.28
1.39
1.11
| 0.694
0.908
0.944
| 0.926
0.894
1.12
| 0.792
1.1
1.18
| |
LMSP03010026 | C26DH Sphingomyelin | 1.37
1.58
1.54
| 1.16
0.976
0.707
| 0.68
0.524
0.728
| 1.56
1.56
1.03
| 1.05
0.829
1.05
| 1.19
1.04
0.971
| 1
1.23
1.53
| |
LMSP0501AA28 | C14DH GlcCer | -
-
-
| -
-
-
| -
-
-
| -
-
-
| -
-
-
| -
-
-
| -
-
-
| |
LMSP0501AA04 | C16DH GlcCer | 0.932
0.897
1.65
| 2.28
2.06
2.78
| 0.788
0.684
0.168
| -
-
-
| -
-
-
| -
-
-
| 1.33
2.17
0.463
| |
LMSP0501AA29 | C18:1DH GlcCer | -
-
-
| -
-
-
| -
-
-
| -
-
-
| -
-
-
| -
-
-
| -
-
-
| |
LMSP0501AA19 | C18DH GlcCer | -
-
-
| -
-
-
| -
-
-
| -
-
-
| -
-
-
| 3.33
6.27
0.467
| -
-
-
| |
LMSP0501AA20 | C20DH GlcCer | 1.79
0.794
0.791
| 2.26
0.574
4.12
| 0.844
1.05
0.441
| 0.969
0.671
0.907
| 0.339
0.684
0.364
| 3.22
9.44
11.6
| 2.35
1.49
3.4
| |
LMSP0501AA21 | C22DH GlcCer | 0.871
0.753
0.588
| 2.51
2.4
3.14
| -
-
-
| 0.381
2.31
4.14
| 0.882
3.45
0.588
| -
-
-
| 5.05
2.14
0.381
| |
LMSP0501AA22 | C24:1DH GlcCer | 1
2.61
1.29
| -
-
-
| 0.171
0.354
0.476
| 1.13
3.03
0.29
| 0.269
0.308
0.346
| 1.97
4.32
1.58
| 1.47
2.07
1.7
| |
LMSP0501AA23 | C24DH GlcCer | -
-
-
| 1.06
8.68
0.049
| 0.098
0.461
0.286
| -
-
-
| 2
1.05
1.41
| 4.3
1.76
2.37
| -
-
-
| |
LMSP0501AA24 | C26:1DH GlcCer | 1.7
0.693
1.14
| 3.59
2.62
3.35
| 1.06
0.212
0.952
| 2.6
1.41
1.65
| 2.09
2.88
3.64
| 13
6.97
8.36
| 3.25
1.03
1.31
| |
LMSP0501AA25 | C26DH GlcCer | 1
0.715
1.03
| 1.48
1.45
1.89
| 0.829
0.681
0.958
| 0.553
0.571
0.545
| 2.41
2.21
1.59
| 2.17
2.68
2.4
| 1.34
1.07
0.985
| |
LMSP01020001 | Sphinganine | 1.2
1.26
0.824
| 1.04
0.977
1.1
| 1.11
1.38
0.942
| 1.5
1.63
1.06
| 0.717
0.879
0.757
| 0.733
0.84
0.856
| 0.628
0.778
1
| |
LMSP01050002 | Sphinganine-P | 1.03
1.25
0.953
| 0.905
0.918
0.864
| 0.898
0.958
1.08
| 1.48
1.26
0.976
| 0.664
0.736
1.36
| 0.976
1.11
0.789
| 0.918
1.64
1.19
| |
LMSP01010001 | Sphingosine | 0.826
0.882
0.885
| 0.747
0.949
1.17
| 1.6
1.37
1.47
| 1.22
0.833
0.76
| 0.613
0.746
0.855
| 1.28
1.23
1.55
| 0.861
0.899
1.04
| |
LMSP01050001 | Sphingosine-P | 0.896
1.03
1
| 0.62
0.85
0.78
| 0.968
1.09
1
| 1.28
0.898
0.874
| 0.567
0.675
0.892
| 1.8
1.42
1.66
| 0.915
1.07
1.08
| |
- | DNA | 1.09
1.05
1.07
| 1.05
1.01
1.02
| 0.983
1.11
1.08
| 1.04
1.05
1.06
| 1.02
0.972
0.948
| 0.864
0.796
0.901
| 0.653
0.668
0.783
| |
- | TNF | 1.57
1.35
1.03
| 3.87
9.42
0.914
| 25.2
52.4
0.958
| 135
145
0.756
| 184
182
0.803
| 173
167
0.867
| 165
163
2.24
|