Microarray analysis of RAW 264.7 cells treated with Kdo2-lipid A (KLA) and compactin (full time course)

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Kdo2-Lipid A / compactin gene array data - treatment:control ratios

KEGG pathway: Valine, leucine and isoleucine biosynthesis (mmu00290)

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Gene symbol    Time course plot Accession Description Treatment 30min 1hr 2hr 4hr 8hr 12hr 24hr
Bcat1
KLA  Compactin  Compactin+KLA
NM_001024468 branched chain aminotransferase 1, cytosolic (Bcat1), transcript variant 1, mRNA [NM_001024468] KLA0.940 0.970 1.050 1.110 1.300 1.350 1.170
Compactin1.000 1.030 1.040 1.130 1.040 1.010 0.990
KLA/Compactin0.980 1.090 1.300 1.320 1.440 1.190 1.100
Bcat1
KLA  Compactin  Compactin+KLA
NM_001024468 branched chain aminotransferase 1, cytosolic (Bcat1), transcript variant 1, mRNA [NM_001024468] KLA1.030 1.060 1.080 1.300 1.770 1.550 1.210
Compactin1.000 1.080 1.130 1.180 1.030 0.970 1.440
KLA/Compactin1.040 1.070 1.100 1.630 1.600 1.160 1.000
Bcat2
KLA  Compactin  Compactin+KLA
NM_009737 branched chain aminotransferase 2, mitochondrial (Bcat2), nuclear gene encoding mitochondrial protein, mRNA [NM_009737] KLA0.780 1.010 1.170 1.070 0.900 1.000 1.090
Compactin1.020 1.090 1.110 1.080 1.050 1.370 0.980
KLA/Compactin1.010 0.990 1.050 1.020 0.960 1.080 1.130
Bcat2
KLA  Compactin  Compactin+KLA
NM_009737 branched chain aminotransferase 2, mitochondrial (Bcat2), nuclear gene encoding mitochondrial protein, mRNA [NM_009737] KLA0.860 1.010 1.000 1.020 0.950 0.970 1.050
Compactin1.030 1.040 0.960 1.130 1.120 1.240 0.990
KLA/Compactin0.960 1.040 0.880 0.980 1.000 1.050 1.130
Bcat2
KLA  Compactin  Compactin+KLA
NM_009737 branched chain aminotransferase 2, mitochondrial (Bcat2), nuclear gene encoding mitochondrial protein, mRNA [NM_009737] KLA1.020 2.730 1.000 1.010 0.990 0.950 1.010
Compactin1.050 0.960 0.960 0.990 0.950 0.950 0.990
KLA/Compactin1.030 1.000 1.030 1.000 0.970 0.920 0.980