LMPD Database

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LMP012737

Gene Information

Entrez Gene ID78968
Gene Namesterol regulatory element binding transcription factor 1
Gene SymbolSrebf1
SpeciesRattus norvegicus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 ISS:UniProtKBCcytoplasm
GO:0031410 IEA:UniProtKB-KWCcytoplasmic vesicle
GO:0005783 IEA:UniProtKB-KWCendoplasmic reticulum
GO:0005794 IEA:UniProtKB-KWCGolgi apparatus
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0043231 IDA:RGDCintracellular membrane-bounded organelle
GO:0005634 IDA:RGDCnucleus
GO:0043234 IDA:RGDCprotein complex
GO:0003682 IDA:RGDFchromatin binding
GO:0003677 ISS:UniProtKBFDNA binding
GO:0032403 IPI:RGDFprotein complex binding
GO:0043565 IDA:RGDFsequence-specific DNA binding
GO:0003700 ISS:HGNCFsequence-specific DNA binding transcription factor activity
GO:0032810 ISS:HGNCFsterol response element binding
GO:0007568 IEP:RGDPaging
GO:0071398 IEP:RGDPcellular response to fatty acid
GO:0032869 IEP:RGDPcellular response to insulin stimulus
GO:0009267 IDA:HGNCPcellular response to starvation
GO:0008203 IMP:RGDPcholesterol metabolic process
GO:0007623 IEA:EnsemblPcircadian rhythm
GO:0008286 IEA:EnsemblPinsulin receptor signaling pathway
GO:0008610 ISS:UniProtKBPlipid biosynthetic process
GO:0030324 IEP:RGDPlung development
GO:0046676 IEA:EnsemblPnegative regulation of insulin secretion
GO:0000122 IEA:EnsemblPnegative regulation of transcription from RNA polymerase II promoter
GO:0045542 IEA:EnsemblPpositive regulation of cholesterol biosynthetic process
GO:0031065 IEA:EnsemblPpositive regulation of histone deacetylation
GO:0045893 IMP:RGDPpositive regulation of transcription, DNA-templated
GO:0045944 IEA:EnsemblPpositive regulation of transcription from RNA polymerase II promoter
GO:0010867 ISS:UniProtKBPpositive regulation of triglyceride biosynthetic process
GO:0019217 IEA:EnsemblPregulation of fatty acid metabolic process
GO:0003062 IEA:EnsemblPregulation of heart rate by chemical signal
GO:0051591 IEP:RGDPresponse to cAMP
GO:0042493 IEP:RGDPresponse to drug
GO:0070542 IEP:RGDPresponse to fatty acid
GO:0032094 IEP:RGDPresponse to food
GO:0033762 IEP:RGDPresponse to glucagon
GO:0009749 IEA:EnsemblPresponse to glucose
GO:0032868 TAS:BHF-UCLPresponse to insulin
GO:0033993 IEP:RGDPresponse to lipid
GO:0014070 IEP:RGDPresponse to organic cyclic compound
GO:0043434 IEP:RGDPresponse to peptide hormone
GO:0032570 IEP:RGDPresponse to progesterone
GO:0032526 IEP:RGDPresponse to retinoic acid
GO:0006351 IEA:UniProtKB-KWPtranscription, DNA-templated
KEGG Pathway Links
KEGG Pathway IDDescription
ko04152AMPK signaling pathway
rno04152AMPK signaling pathway
ko04910Insulin signaling pathway
rno04910Insulin signaling pathway
ko04932Non-alcoholic fatty liver disease (NAFLD)
rno04932Non-alcoholic fatty liver disease (NAFLD)
REACTOME Pathway Links
REACTOME Pathway IDDescription
5954496Activation of gene expression by SREBF (SREBP)
5954223Circadian Clock
5953533Developmental Biology
5953288Fatty acid, triacylglycerol, and ketone body metabolism
5953250Metabolism
5953289Metabolism of lipids and lipoproteins
5954333PPARA activates gene expression
5954497Regulation of cholesterol biosynthesis by SREBP (SREBF)
5954222Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
5954225RORA activates circadian gene expression
5954166Transcriptional regulation of white adipocyte differentiation