Lipidomics studies on macrophages - bone marrow-derived macrophages treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

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Averages of biological replicates - (GP) Glycerophospholipids

Legend:graph_icon: View data/graphs for replicatesgraph_icon: View time course graphs for averages of biological replicates
Ctrl:Untreated BMDM cells (control)
25-OHC: Cells treated with 25-OH-cholesterol at time 0
*: BMDM cells in lipid-depleted media containing compactin
25-OHC*: cells in lipid-depleted media containing compactin and treated with 25-OHC at time 0
PA | PC | PE | PG | PI | PS | DNA

DetailsTime course graph
(ave of biol. reps) 		LM_ID Name 25-OHC*
*
25-OHC
Ctrl
 0 hrs		 25-OHC*
*
25-OHC
Ctrl
 30 min		 25-OHC*
*
25-OHC
Ctrl
 1 hr		 25-OHC*
*
25-OHC
Ctrl
 2 hrs		 25-OHC*
*
25-OHC
Ctrl
 4 hrs		 25-OHC*
*
25-OHC
Ctrl
 8 hrs		 25-OHC*
*
25-OHC
Ctrl
 12 hrs		 25-OHC*
*
25-OHC
Ctrl
 24 hrs
Units
. . . .

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- LPE(18:0) -
55.7
-
61		 59.3
80.1
85.5
58.7		 79.3
56.1
45.6
75.6		 157
200
169
60.1		 176
200
182
183		 209
147
323
126		 35.6
22.2
262
150		 40.2
38.1
51.3
43		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- LPE(18:1) -
195
-
614		 90.8
122
145
126		 131
119
130
141		 345
327
261
98.2		 530
415
437
462		 609
396
772
310		 307
377
341
322		 570
417
341
428		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- LPE(20:3) -
87.4
-
276		 34.6
35.7
46.4
44.8		 57.7
36.6
47.2
51.2		 138
126
95.6
36.4		 231
156
190
201		 247
150
295
130		 109
156
127
134		 179
148
131
180		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- LPE(20:4) -
197
-
767		 64.8
85.4
123
115		 96.8
98
135
122		 277
209
211
85.9		 437
306
375
426		 452
278
669
263		 258
360
243
265		 418
358
302
475		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- LPE(22:4) -
58.5
-
207		 29.4
34.3
45.6
39.4		 53.3
32.9
44.1
46		 91.9
83.7
68.3
30		 147
107
150
152		 158
96.1
203
86.3		 68.4
89.6
95
96.9		 99.7
73.3
85.7
105		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- LPE(22:5) -
89.7
-
336		 34.1
46.6
52.5
52.6		 54
57.1
64.4
69.1		 136
113
99.6
44.4		 214
143
183
207		 223
132
315
121		 113
151
121
132		 194
146
136
189		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- LPE(22:6) -
99
-
348		 34.8
43
58.8
51.6		 57.2
47.5
60.1
60.8		 144
110
92.4
39.4		 223
157
178
206		 229
140
287
119		 119
174
110
122		 194
154
143
192		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(32:0) -
41.4
-
48.1		 49.6
61.9
54.7
45.3		 60.8
54.9
54
59.9		 57.9
42
59.9
58.7		 39
45.4
40.8
41		 38.7
50.1
38.6
43.8		 59
52.4
43.8
54.5		 61.7
55.8
65.4
53.8		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(32:1) -
68.3
-
80.3		 73.8
101
93.7
66.6		 101
92.8
75
106		 86
83.9
112
83.8		 65.5
77.9
79.6
70.7		 65.5
78.6
64
67.6		 83.1
79.7
75
82.2		 105
91.8
98.3
85.9		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(34:0) -
48
-
74.1		 42.7
61.4
63.9
41.2		 54.3
57.6
37.8
71.9		 78.7
79.4
89
47.4		 62.8
73.7
75
76.7		 57.4
70.5
60.9
55.1		 23.7
23.5
46.5
53.4		 31
24.6
34.2
45.1		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(34:1) -
245
-
323		 284
322
313
242		 365
317
298
360		 259
229
310
255		 173
201
221
197		 215
267
203
176		 282
320
252
257		 447
329
351
297		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(34:1e)/PE(34:0p) -
127
-
126		 133
165
158
130		 148
144
158
161		 150
87
162
144		 95.8
117
84
99.6		 108
146
84.9
129		 122
140
148
150		 140
96.4
110
110		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(34:2) -
117
-
145		 146
173
161
123		 179
155
147
178		 125
119
159
131		 87.6
95.2
119
96.2		 106
125
94.8
87.7		 123
141
119
122		 185
146
161
141		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(34:2e)/PE(34:1p) -
263
-
116		 375
328
313
287		 644
351
413
381		 206
159
230
382		 115
136
144
108		 234
245
98.6
103		 300
414
208
172		 429
336
342
271		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(34:3e)/PE(34:2p) -
51.5
-
25.9		 78
69.3
66.4
60.3		 128
74.5
86.4
82.3		 48.2
35.5
53.9
82.2		 28.2
30.3
32.4
28.2		 52.9
56.8
23.7
25.4		 52.9
80.4
48
37.2		 77.3
59.9
63
50.6		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(36:0) -
189
-
173		 153
164
146
147		 -
37.8
94.4
70.1		 190
-
200
125		 147
198
-
170		 135
261
142
106		 75.3
118
36.5
86.2		 42.9
33.9
121
108		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(36:0)/PE(38:6p) -
201
-
258		 254
337
353
238		 351
319
279
403		 342
231
385
276		 213
213
221
212		 257
241
150
180		 178
211
241
199		 285
244
229
211		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(36:1) -
541
-
733		 518
602
624
476		 808
598
544
686		 624
450
711
554		 429
464
445
465		 489
601
497
351		 539
618
463
461		 837
681
665
567		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(36:2) -
594
-
786		 660
728
732
580		 857
727
739
769		 553
398
662
678		 374
414
402
424		 499
667
473
409		 708
803
571
618		 997
828
833
715		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(36:2e)/PE(36:1p) -
185
-
148		 231
263
252
205		 321
216
231
257		 201
153
223
228		 118
135
142
118		 184
211
109
109		 231
247
166
150		 310
261
251
206		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(36:3) -
128
-
185		 150
174
183
128		 192
173
164
199		 150
126
194
156		 94.8
105
139
119		 126
152
141
110		 148
167
148
152		 200
169
219
175		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(36:3e)/PE(36:2p) -
142
-
105		 195
209
212
167		 250
167
204
198		 145
113
162
188		 85.1
99.2
105
87.8		 153
165
71.8
85.4		 191
202
133
123		 222
191
190
152		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(36:4) -
109
-
148		 116
133
155
116		 159
138
152
164		 110
88.6
157
132		 70.8
80.8
109
92.8		 111
135
117
88.2		 151
154
163
148		 247
167
266
176		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(36:4e)/PE(36:3p) -
120
-
95.6		 163
183
193
152		 219
143
167
197		 138
113
180
165		 78.5
96.2
113
91.7		 126
145
72.9
81.2		 135
152
116
106		 175
155
164
140		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(36:5e)/PE(36:4p) -
196
-
134		 275
275
315
260		 371
233
341
327		 157
136
226
302		 87.2
117
138
112		 165
203
90.2
107		 243
294
174
160		 289
271
355
292		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(38:1) -
162
-
133		 126
124
125
133		 -
36.9
69.2
48.4		 128
-
134
96.7		 71.5
139
-
96.7		 65.2
194
97.1
74.8		 58.9
84.6
26.4
63.9		 28.8
28.9
69.1
92		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(38:2) -
138
-
219		 108
139
161
113		 140
142
107
170		 162
135
182
111		 127
124
150
133		 124
147
124
108		 88.4
111
101
102		 143
116
113
107		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(38:3) -
318
-
527		 256
329
381
274		 380
311
276
433		 383
295
462
294		 273
277
361
319		 276
324
330
255		 261
285
266
270		 389
322
337
312		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(38:3e)/PE(38:2p) -
140
-
183		 150
182
186
144		 174
147
129
182		 191
164
231
147		 138
161
217
143		 149
187
139
135		 98.7
108
124
143		 130
116
104
107		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(38:4) -
431
-
718		 403
483
593
429		 597
483
492
646		 493
390
642
460		 339
354
468
410		 378
472
474
366		 445
466
446
431		 684
506
685
530		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(38:5) -
207
-
337		 207
241
302
208		 297
234
249
327		 245
210
345
234		 171
187
238
216		 201
245
236
190		 187
216
241
236		 272
229
314
265		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(38:5e)/PE(38:4p) -
260
-
292		 335
415
456
333		 403
295
342
443		 356
306
480
353		 223
269
343
259		 293
339
200
237		 208
247
272
264		 267
255
294
276		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(38:6) -
94
-
139		 88.5
113
132
88.1		 133
107
99.7
144		 119
103
163
107		 83.5
96.2
132
102		 91.4
108
102
88.1		 79.1
82.1
99.5
97.2		 115
82.7
113
95.4		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(38:6e)/PE(38:5p) -
204
-
156		 320
347
388
289		 409
321
336
407		 287
238
346
337		 135
163
243
183		 157
216
92
148		 184
232
164
111		 216
187
267
237		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(40:4) -
91.8
-
175		 65.3
89.5
114
76.3		 82.1
82
76.6
118		 93.3
75.6
124
74.4		 79.9
72.7
103
92.5		 80
90.6
92.1
66.7		 63.3
63.4
70.7
66.7		 97.6
75.6
83.1
74.7		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(40:5) -
143
-
272		 107
141
178
129		 142
132
127
188		 151
125
205
125		 126
117
154
146		 127
157
149
110		 114
114
122
115		 169
131
146
123		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(40:5e)/PE(40:4p) -
138
-
166		 135
191
245
159		 172
156
153
227		 182
184
280
162		 141
171
241
178		 139
198
156
141		 67.1
82.2
128
143		 83.8
84.1
79.2
97.5		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(40:6) -
182
-
318		 143
178
228
161		 210
178
163
242		 196
158
255
161		 154
149
200
178		 160
192
193
134		 137
140
158
147		 204
156
194
159		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(40:6e)/PE(40:5p) -
186
-
179		 179
256
276
175		 221
201
165
264		 238
229
311
187		 169
211
271
195		 142
199
166
164		 101
111
129
134		 141
108
148
146		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(40:7) -
81.1
-
133		 64.4
81
102
69.2		 93.3
82.2
72.2
104		 91.4
71.7
126
79.8		 73.1
73.4
104
86.1		 70.6
95.7
93.3
71		 56.5
65.2
70.2
74		 72.6
66.1
79.5
73.3		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(40:7e)/PE(40:6p) -
586
-
609		 506
811
920
495		 684
672
485
881		 562
638
916
495		 445
489
785
528		 363
410
322
410		 264
288
349
279		 417
341
348
352		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PE(40:8e)/PE(40:7p) -
102
-
133		 137
158
195
112		 129
144
139
192		 185
113
214
146		 107
110
136
114		 104
104
88.4
103		 92.4
101
98.2
99.5		 115
125
118
117		 pmol/sample