Lipidomics studies on macrophages - bone marrow-derived macrophages treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

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Averages of biological replicates - (GP) Glycerophospholipids

Legend:graph_icon: View data/graphs for replicatesgraph_icon: View time course graphs for averages of biological replicates
Ctrl:Untreated BMDM cells (control)
25-OHC: Cells treated with 25-OH-cholesterol at time 0
*: BMDM cells in lipid-depleted media containing compactin
25-OHC*: cells in lipid-depleted media containing compactin and treated with 25-OHC at time 0
PA | PC | PE | PG | PI | PS | DNA

DetailsTime course graph
(ave of biol. reps) 		LM_ID Name 25-OHC*
*
25-OHC
Ctrl
 0 hrs		 25-OHC*
*
25-OHC
Ctrl
 30 min		 25-OHC*
*
25-OHC
Ctrl
 1 hr		 25-OHC*
*
25-OHC
Ctrl
 2 hrs		 25-OHC*
*
25-OHC
Ctrl
 4 hrs		 25-OHC*
*
25-OHC
Ctrl
 8 hrs		 25-OHC*
*
25-OHC
Ctrl
 12 hrs		 25-OHC*
*
25-OHC
Ctrl
 24 hrs
Units
. . . .

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PS(32:0) -
61.7
-
49.8		 42.3
51.1
53.8
41.9		 56.1
44.3
43.5
51.8		 37.2
48.7
54.5
43.3		 34
37.3
52.8
44.5		 31.2
30.3
27.5
29.5		 20.4
30.2
25.8
31.1		 22.8
23
21
24.4		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PS(32:1) -
69.9
-
73		 61.4
76.1
78.8
56.6		 65
60.4
53.5
71.3		 54.5
61.9
78.2
52.8		 50.5
53.3
71
58.2		 50.6
45.3
45.2
38.9		 50.7
62.7
54.3
49.1		 62.5
45.6
43.6
52.9		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PS(34:0) -
93.4
-
113		 66.2
122
128
73.3		 102
95.2
67.8
118		 71
113
136
65.5		 78.1
83.5
134
104		 59.4
53.1
59.9
48.9		 27
29.2
56.6
60.3		 24.3
21.8
22.1
34.1		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PS(34:1) -
482
-
651		 465
689
716
432		 613
510
470
647		 400
432
613
472		 330
366
542
383		 388
360
296
266		 514
523
412
370		 630
473
452
506		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PS(34:2) -
78.4
-
95.6		 66.1
95.6
100
67.2		 79.2
70.2
70
94.4		 54.1
64.4
87
68.8		 50.5
53
81.4
59.8		 56.9
50.2
45.9
39.6		 58.7
66
60.7
55.3		 62.1
59.8
49.1
66		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PS(36:1) -
1783
-
2466		 1641
2360
2588
1555		 2249
1871
1643
2356		 1273
1539
2154
1693		 1080
1197
1960
1317		 1223
1141
948
898		 1801
1929
1350
1162		 2333
1857
1722
1747		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PS(36:2) -
528
-
787		 523
759
816
496		 656
559
538
736		 402
482
692
558		 334
368
616
408		 394
350
307
284		 517
559
444
391		 600
494
491
557		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PS(36:4) -
64
-
114		 60.5
73.8
81.2
58.7		 70.1
59.6
58.6
71.4		 48.4
49.5
73.4
57.4		 40.6
45.3
65.9
45.2		 44.2
45.3
41.4
29.6		 52.7
63.1
52
42.8		 64.3
52.1
51.4
52.8		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PS(38:0) -
44.3
-
49.5		 31.7
38.8
42.9
35.9		 43.2
31.7
31.3
36.7		 27.2
39.4
33.5
25.3		 30.1
28.3
38.4
34.3		 27
24.3
22.2
21.2		 17.6
26.9
26.3
25.6		 22.3
18.5
25
19.7		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PS(38:1) -
98.7
-
119		 77.3
132
144
75.9		 103
102
78
124		 65.7
108
122
70.9		 71.9
73.2
126
91.5		 69.1
61.7
50.5
49.3		 54.2
52.7
61.1
61.2		 64.4
45.5
46.5
53.7		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PS(38:2) -
157
-
224		 135
241
271
133		 199
187
142
219		 126
209
236
133		 137
140
243
180		 128
113
101
94.3		 114
107
127
120		 118
100
85.5
101		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PS(38:3) -
356
-
523		 312
531
605
308		 441
404
324
519		 275
430
554
312		 289
312
556
388		 284
244
231
205		 232
271
299
275		 313
252
269
311		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PS(38:4) -
435
-
824		 417
618
742
427		 548
470
434
627		 343
476
678
413		 330
359
645
420		 330
297
287
233		 346
391
390
331		 447
322
373
399		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PS(38:5) -
108
-
197		 108
144
160
107		 125
107
110
139		 81.5
115
146
94.2		 84.1
88.5
145
106		 83.5
74.8
76
62.3		 72.6
92.1
90.3
81.5		 91.3
70.9
81.5
85.4		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PS(38:6) -
44.6
-
49.1		 30.5
44.5
49.3
32.1		 41.8
32.9
27.3
40		 24.1
32.2
41.9
26.9		 25.5
24.3
39.8
30.5		 25.5
23
21.5
18.2		 22.6
28.1
27.4
23.3		 24.3
19.1
25.7
24		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PS(40:3) -
54.2
-
61.3		 36.1
66.3
74.1
40.8		 47.8
52
36.6
59		 32.3
56.6
64.1
35.3		 36.4
35.9
65.3
53.4		 34.6
31.9
33.3
30		 24.7
22.7
39.9
33		 30.7
22.1
20.9
25.4		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PS(40:4) -
163
-
216		 141
250
279
138		 185
185
142
230		 116
201
246
133		 134
134
239
185		 126
113
108
97.9		 96.2
101
137
120		 115
92.5
98.7
106		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PS(40:5) -
292
-
391		 246
428
496
257		 342
341
269
423		 213
358
445
252		 241
240
450
327		 231
207
197
185		 204
220
264
239		 261
200
222
250		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PS(40:6) -
382
-
508		 334
563
644
327		 469
442
347
541		 286
441
578
343		 306
315
574
399		 303
257
252
222		 292
317
340
298		 384
272
317
339		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- PS(40:7) -
62.2
-
97.4		 51.3
76.6
86.5
56.9		 66.2
58.3
54.3
74.6		 41.2
61.1
78.2
45.9		 43.2
43.9
80.8
56.9		 43.2
38.4
36.4
32.8		 32.6
42.6
47.1
45.1		 42.7
31.6
44.4
43.2		 pmol/sample