Microarray analysis of bone marrow-derived macrophage cells treated with Kdo₂-lipid A (KLA) and ATP

Kdo₂-Lipid A / ATP gene array data - treatment:control ratios

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Gene symbol	Time course plot	Accession	Description	Treatment	15min	30min	1hr	2hr	4hr	8hr	20hr
Acaca	KLA ATP ATP+KLA	NM_133360	acetyl-Coenzyme A carboxylase alpha (Acaca), mRNA [NM_133360]	KLA	.99	.94	.95	.93	.95	1.00	1.00
				ATP	.98	.97	.96	.93	.92	.96	.99
				KLA/ATP	1.01	.96	.99	.92	.93	.94	.91

Acacb	KLA ATP ATP+KLA	NM_133904		acetyl-Coenzyme A carboxylase beta (Acacb), mRNA [NM_133904]	KLA	1.01	.93	1.00	.99	.95	1.03	.92
					ATP	.96	1.04	1.05	.98	1.04	1.11	1.05
					KLA/ATP	.90	1.01	1.05	1.03	.97	.96	1.08

Fasn	KLA ATP ATP+KLA	NM_007988	fatty acid synthase (Fasn), mRNA [NM_007988]	KLA	.51	.49	.46	.44	.41	.35	.41
				ATP	.98	.93	.98	.96	.83	.67	.62
				KLA/ATP	.52	.47	.48	.58	.51	.44	.25

Mcat	KLA ATP ATP+KLA	NM_001030014		malonyl CoA:ACP acyltransferase (mitochondrial) (Mcat), nuclear gene encoding mitochondrial protein, mRNA [NM_001030014]	KLA	1.51	1.53	1.49	1.38	1.39	1.52	1.29
					ATP	.97	.98	.85	.78	.40	.85	1.23
					KLA/ATP	1.51	1.55	1.30	1.39	1.04	1.18	1.84

Olah	KLA ATP ATP+KLA	NM_145921	oleoyl-ACP hydrolase (Olah), mRNA [NM_145921]	KLA	1.09	1.08	.99	1.00	.96	1.07	1.10
				ATP	.93	1.00	1.07	1.07	1.00	1.02	1.01
				KLA/ATP	1.03	1.03	1.01	.97	.99	1.02	.94

Oxsm	KLA ATP ATP+KLA	NM_027695		3-oxoacyl-ACP synthase, mitochondrial (Oxsm), nuclear gene encoding mitochondrial protein, mRNA [NM_027695]	KLA	1.05	1.03	1.11	1.27	1.24	1.26	1.18
					ATP	.94	.81	.79	.56	.47	1.05	1.43
					KLA/ATP	.99	.98	.95	.76	.59	.84	1.27