Partial Spectra DB

About Partial Spectra DB

Partial Spectra DB is a specialized spectral database focused on lipids that are underrepresented in conventional lipidomics research because they are only partially structurally annotated. By aggregating these spectra alongside expert-curated annotations and contextual information it facilitates the discovery and identification of novel lipid species that may otherwise remain overlooked.

While mammalian lipids dominate most analyses and their MS/MS fragmentation pattern is usually well described, many other lipids exist in other biological systems/organisms which are less investigated, where their structures are only partly-annotated. Similarly, epilipids —lipids modified by enzymatic or environmental processes are not always well annotated structurally. These lipids often feature distinctive substructure characteristics detectable by mass spectrometry, yet the spectral data obtained are insufficient to fully resolve the exact structural configuration. These spectra and associated metadata offer valuable insights into their biology and biochemistry and are essential for facilitating further research into their properties and their associations with health and disease.