Microarray analysis of bone marrow-derived macrophage cells treated with Kdo2-lipid A (KLA) and ATP

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Kdo2-Lipid A / ATP gene array data - treatment:control ratios

KEGG pathway: Cyanoamino acid metabolism (mmu00460)

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Gene symbol    Time course plot Accession Description Treatment 15min 30min 1hr 2hr 4hr 8hr 20hr
Ggt1
KLA  ATP  ATP+KLA
 NM_008116 gamma-glutamyltransferase 1 (Ggt1), mRNA [NM_008116] KLA 1.03 1.00 1.00 1.05 1.00 1.02 1.02
ATP 1.00 1.00 .96 1.00 1.03 1.02 .99
KLA/ATP .98 .99 1.04 1.00 .99 .98 .98
Ggt5
KLA  ATP  ATP+KLA
 NM_011820 gamma-glutamyltransferase 5 (Ggt5), mRNA [NM_011820] KLA .89 .91 .92 .89 .86 .79 .58
ATP 1.00 1.03 .93 .97 .84 .80 .59
KLA/ATP 1.00 .92 .93 .98 .83 .79 .68
Ggt6
KLA  ATP  ATP+KLA
 NM_027819 gamma-glutamyltransferase 6 (Ggt6), mRNA [NM_027819] KLA 1.03 .90 .98 1.07 1.00 1.02 .98
ATP 1.02 1.07 .90 1.02 1.03 1.03 .94
KLA/ATP .99 1.04 .98 .97 1.02 1.01 .96
Ggt7
KLA  ATP  ATP+KLA
 NM_144786 gamma-glutamyltransferase 7 (Ggt7), mRNA [NM_144786] KLA .96 1.03 .97 1.01 1.00 .98 .89
ATP 1.03 1.02 1.01 .92 .94 .97 1.00
KLA/ATP .98 .95 1.05 .89 .92 .94 .94
Shmt1
KLA  ATP  ATP+KLA
 NM_009171 serine hydroxymethyltransferase 1 (soluble) (Shmt1), mRNA [NM_009171] KLA .85 .89 .82 .83 .82 .88 .83
ATP .93 .81 .85 .82 .85 .86 .72
KLA/ATP .81 .83 .91 .86 .85 .86 .72
Shmt2
KLA  ATP  ATP+KLA
 NM_028230 serine hydroxymethyltransferase 2 (mitochondrial) (Shmt2), nuclear gene encoding mitochondrial protein, mRNA [NM_028230] KLA .82 .90 .78 .63 .51 .39 .63
ATP 1.04 1.21 .97 1.44 1.32 .85 .64
KLA/ATP .94 .92 .62 1.01 .59 .49 .32