Microarray analysis of bone marrow-derived macrophage cells treated with Kdo2-lipid A (KLA) and ATP

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Kdo2-Lipid A / ATP gene array data - treatment:control ratios

KEGG pathway: Cytosolic DNA-sensing pathway (mmu04623)

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Gene symbol    Time course plot Accession Description Treatment 15min 30min 1hr 2hr 4hr 8hr 20hr
Adar
KLA  ATP  ATP+KLA
NM_001038587 adenosine deaminase, RNA-specific (Adar), transcript variant 1, mRNA [NM_001038587] KLA 5.28 5.13 4.53 4.02 4.14 3.44 2.88
ATP 1.30 1.41 1.07 1.26 1.55 3.27 2.25
KLA/ATP 5.63 6.36 4.32 6.87 6.03 6.89 6.51
Adar
KLA  ATP  ATP+KLA
NM_019655 adenosine deaminase, RNA-specific (Adar), transcript variant 1, mRNA [NM_019655] KLA 4.04 4.23 4.16 3.97 3.67 3.70 3.37
ATP 1.05 1.05 .80 .67 .74 3.23 3.93
KLA/ATP 4.62 4.13 3.21 3.21 2.14 5.80 8.51
Aim2
KLA  ATP  ATP+KLA
NM_001013779 absent in melanoma 2 (Aim2), mRNA [NM_001013779] KLA 1.10 1.06 1.02 1.00 1.00 1.02 .98
ATP 1.04 1.05 .99 1.01 .97 1.10 1.01
KLA/ATP 1.03 1.02 1.07 .95 1.02 1.00 1.06
Casp1
KLA  ATP  ATP+KLA
NM_009807 caspase 1 (Casp1), mRNA [NM_009807] KLA 4.27 4.63 5.39 6.07 5.87 5.49 2.96
ATP .93 .87 1.01 .80 1.05 3.11 2.77
KLA/ATP 4.31 4.18 5.40 4.00 4.66 4.90 7.20
Ccl4
KLA  ATP  ATP+KLA
NM_013652 chemokine (C-C motif) ligand 4 (Ccl4), mRNA [NM_013652] KLA 68.93 60.20 52.12 67.06 35.78 15.78 8.82
ATP 2.26 3.82 16.88 43.14 26.67 9.47 6.75
KLA/ATP 59.57 71.75 133.98 193.53 81.76 15.96 7.62
Ccl5
KLA  ATP  ATP+KLA
M77747 rantes mRNA, complete cds. [M77747] KLA 63.18 60.41 56.25 63.63 58.00 66.51 67.20
ATP .91 1.08 1.25 1.90 4.34 16.10 26.07
KLA/ATP 55.92 63.34 72.91 65.68 70.81 71.97 81.34
Ccl5
KLA  ATP  ATP+KLA
NM_013653 chemokine (C-C motif) ligand 5 (Ccl5), mRNA [NM_013653] KLA 40.31 35.22 27.92 38.59 29.29 37.98 28.83
ATP .86 .92 1.43 1.66 3.86 15.09 16.66
KLA/ATP 32.14 31.72 47.19 35.89 42.00 46.15 43.89
Chuk
KLA  ATP  ATP+KLA
NM_007700 conserved helix-loop-helix ubiquitous kinase (Chuk), mRNA [NM_007700] KLA 1.32 1.42 1.41 1.17 1.32 1.22 1.40
ATP 1.22 1.30 1.18 .97 1.02 1.00 1.37
KLA/ATP 1.56 1.61 1.21 1.09 .83 .84 1.17
Cxcl10
KLA  ATP  ATP+KLA
NM_021274 chemokine (C-X-C motif) ligand 10 (Cxcl10), mRNA [NM_021274] KLA 986.69 854.98 711.49 799.39 542.62 686.82 183.27
ATP .98 1.71 9.85 73.04 100.42 184.63 8.33
KLA/ATP 842.13 793.12 ###.## ###.## ###.## 715.22 496.10
D430028G
21Rik
KLA  ATP  ATP+KLA
NM_144888 RIKEN cDNA D430028G21 gene (D430028G21Rik), mRNA [NM_144888] KLA .56 .54 .61 .60 .74 1.03 1.06
ATP 1.07 .99 .69 .66 .48 .96 1.38
KLA/ATP .61 .60 .38 .41 .42 1.00 1.40
Ddx58
KLA  ATP  ATP+KLA
NM_172689 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Ddx58), mRNA [NM_172689] KLA 8.80 9.12 9.70 9.96 9.92 7.85 5.67
ATP 1.06 .89 .97 .89 .80 3.03 3.67
KLA/ATP 9.18 9.23 10.31 9.25 7.29 6.93 8.99
Ifi202b
KLA  ATP  ATP+KLA
NM_011940 interferon activated gene 202B (Ifi202b), transcript variant 2, mRNA [NM_011940] KLA 1.53 1.32 1.43 1.47 1.22 1.26 1.29
ATP 1.02 1.05 1.16 1.57 24.15 53.46 4.08
KLA/ATP 1.61 1.45 2.40 7.87 5.30 5.54 2.58
Ifna12
KLA  ATP  ATP+KLA
NM_177361 interferon alpha 12 (Ifna12), mRNA [NM_177361] KLA 1.25 1.26 1.34 1.16 1.06 1.10 1.09
ATP 1.01 .97 1.07 1.09 1.17 1.20 1.07
KLA/ATP 1.12 1.29 1.72 1.54 1.59 1.56 1.05
Ifna13
KLA  ATP  ATP+KLA
NM_177347 interferon alpha 13 (Ifna13), mRNA [NM_177347] KLA 1.32 1.27 1.26 1.34 1.15 1.24 1.20
ATP .95 1.08 1.29 1.79 1.41 1.22 1.08
KLA/ATP 1.36 1.35 2.04 2.81 2.07 1.44 1.19
Ifna2
KLA  ATP  ATP+KLA
K01411 gb|Mouse alpha-interferon (MuIFN-alpha), 3 cds & untranslated mRNA [K01411] KLA 1.02 1.03 1.10 .96 .93 .99 1.01
ATP 1.02 .98 1.00 .98 1.02 .97 .95
KLA/ATP 1.02 1.04 1.18 1.08 1.13 1.04 1.01
Ifna2
KLA  ATP  ATP+KLA
NM_010503 interferon alpha 2 (Ifna2), mRNA [NM_010503] KLA 1.08 1.06 1.07 1.06 .98 1.02 1.05
ATP .94 1.06 1.11 1.30 1.24 1.25 1.21
KLA/ATP 1.03 1.20 1.19 1.35 1.52 1.60 1.18
Ifna4
KLA  ATP  ATP+KLA
NM_010504 interferon alpha 4 (Ifna4), mRNA [NM_010504] KLA .99 1.04 1.05 .97 1.00 .96 .99
ATP 1.01 .96 .98 1.01 1.00 1.00 .97
KLA/ATP 1.10 1.09 1.05 1.04 1.01 .97 1.01
Ifna5
KLA  ATP  ATP+KLA
NM_010505 interferon alpha 5 (Ifna5), mRNA [NM_010505] KLA 1.15 1.23 1.51 1.26 1.03 1.06 1.05
ATP .99 .94 1.11 1.00 1.09 1.07 1.03
KLA/ATP 1.12 1.29 1.46 1.47 1.24 1.32 1.03
Ifna9
KLA  ATP  ATP+KLA
NM_010507 interferon alpha 9 (Ifna9), mRNA [NM_010507] KLA 1.05 1.09 1.20 1.06 1.08 1.06 1.02
ATP .99 1.08 1.18 1.21 1.09 .99 .97
KLA/ATP 1.09 1.23 1.19 1.24 1.18 1.16 1.04
Ifnab
KLA  ATP  ATP+KLA
BC116864 interferon alpha B, mRNA (cDNA clone MGC:151241 IMAGE:40126183), complete cds [BC116864] KLA 1.20 1.33 1.29 1.30 1.20 1.20 1.08
ATP .99 .99 1.00 1.25 1.13 1.19 1.04
KLA/ATP 1.30 1.39 1.44 1.48 1.49 1.54 1.22
Ifnb1
KLA  ATP  ATP+KLA
NM_010510 interferon beta 1, fibroblast (Ifnb1), mRNA [NM_010510] KLA 49.82 46.57 34.05 16.05 5.94 7.31 8.49
ATP .99 1.02 1.89 4.78 6.31 4.44 1.79
KLA/ATP 49.22 61.83 134.08 144.05 110.96 31.78 11.24
Ikbkb
KLA  ATP  ATP+KLA
NM_010546 inhibitor of kappaB kinase beta (Ikbkb), mRNA [NM_010546] KLA 1.88 2.10 2.14 1.83 1.73 1.31 1.19
ATP .81 .74 .55 .49 .59 1.05 .96
KLA/ATP 1.86 1.73 1.39 1.12 .89 1.17 1.24
Ikbke
KLA  ATP  ATP+KLA
NM_019777 inhibitor of kappaB kinase epsilon (Ikbke), mRNA [NM_019777] KLA 6.03 5.91 6.38 6.89 7.05 6.70 4.74
ATP 1.02 1.11 .82 1.16 1.18 2.08 1.90
KLA/ATP 6.04 6.71 5.69 5.30 2.49 2.33 5.43
Ikbkg
KLA  ATP  ATP+KLA
AK042138 3 days neonate thymus cDNA, RIKEN full-length enriched library, clone:A630062P04 product:unclassifiable, full insert sequence. [AK042138] KLA .92 .87 .78 .78 .87 .88 .62
ATP .84 .71 .80 .50 1.15 2.33 .61
KLA/ATP .72 .69 .74 .48 1.06 1.97 .68
Ikbkg
KLA  ATP  ATP+KLA
NM_010547 inhibitor of kappaB kinase gamma (Ikbkg), transcript variant 1, mRNA [NM_010547] KLA 1.51 1.63 1.74 1.83 1.83 1.73 1.72
ATP .80 .79 .82 .75 .66 2.58 2.37
KLA/ATP 1.43 1.42 1.17 1.04 .71 1.54 3.17
Ikbkg
KLA  ATP  ATP+KLA
NM_178590 inhibitor of kappaB kinase gamma (Ikbkg), transcript variant 2, mRNA [NM_178590] KLA .84 .93 .86 .91 1.03 .89 .88
ATP 1.03 .98 .68 .56 .51 .93 .68
KLA/ATP .89 .81 .55 .52 .41 .67 .65
Il18
KLA  ATP  ATP+KLA
NM_008360 interleukin 18 (Il18), mRNA [NM_008360] KLA 12.14 11.96 12.28 12.96 12.23 7.84 2.40
ATP 1.06 .96 1.13 1.04 .92 1.67 2.29
KLA/ATP 11.55 11.63 13.03 9.98 9.08 6.50 6.72
Il1b
KLA  ATP  ATP+KLA
NM_008361 interleukin 1 beta (Il1b), mRNA [NM_008361] KLA 149.78 133.59 100.91 116.58 86.48 89.37 64.72
ATP 3.49 13.96 61.44 70.91 82.12 162.79 28.18
KLA/ATP 130.32 139.00 219.12 148.17 165.44 172.57 146.98
Il33
KLA  ATP  ATP+KLA
NM_133775 interleukin 33 (Il33), mRNA [NM_133775] KLA 2.34 2.27 2.62 2.36 1.87 1.34 1.07
ATP 1.13 .97 1.07 1.09 2.09 9.35 1.19
KLA/ATP 2.38 2.26 2.15 2.10 2.48 7.29 3.89
Il6
KLA  ATP  ATP+KLA
NM_031168 interleukin 6 (Il6), mRNA [NM_031168] KLA 352.99 378.70 276.81 168.47 59.99 18.66 8.27
ATP 1.04 1.08 2.28 3.69 30.40 161.93 2.11
KLA/ATP 334.28 528.66 ###.## 935.86 302.45 355.36 99.65
Irf3
KLA  ATP  ATP+KLA
ENSMUST00000107835 ens|Interferon regulatory factor 3 (IRF-3). [Source:Uniprot/SWISSPROT;Acc:P70671] [ENSMUST00000107835] KLA .55 .56 .60 .72 .88 .88 .98
ATP .77 .58 .50 .46 .80 .97 1.03
KLA/ATP .51 .46 .49 .53 .92 .85 .79
Irf3
KLA  ATP  ATP+KLA
NM_016849 interferon regulatory factor 3 (Irf3), mRNA [NM_016849] KLA .79 .75 .71 .83 .88 1.07 .99
ATP .92 .84 .88 .61 .54 1.27 1.22
KLA/ATP .78 .78 .75 .58 .70 1.13 1.38
Irf7
KLA  ATP  ATP+KLA
NM_016850 interferon regulatory factor 7 (Irf7), mRNA [NM_016850] KLA 4.90 4.72 5.85 5.82 7.67 10.64 15.44
ATP 1.14 1.10 .86 1.18 .96 2.46 12.17
KLA/ATP 5.41 5.22 4.15 6.29 5.31 9.74 29.08
Mm.11668
7
KLA  ATP  ATP+KLA
11496252 Unknown KLA 9.62 8.06 7.65 9.44 8.65 9.18 7.13
ATP 1.16 .96 1.12 1.01 .93 4.51 6.87
KLA/ATP 7.87 8.06 11.82 11.13 11.62 9.36 11.15
Mm.21511
5
KLA  ATP  ATP+KLA
146149315 Unknown KLA .94 .93 .96 .95 .89 .95 1.08
ATP 1.02 .93 1.00 .83 .78 .92 1.58
KLA/ATP .90 .96 .93 .85 .77 .83 .83
Mm.3458
KLA  ATP  ATP+KLA
119226250 Unknown KLA .85 .78 .75 .84 .74 .81 .79
ATP .97 .83 1.09 .93 2.03 1.96 .89
KLA/ATP .81 .72 .89 .63 1.72 1.77 .79
Mm.37708
7
KLA  ATP  ATP+KLA
158631169 Unknown KLA .98 .98 1.06 1.06 .91 .97 1.04
ATP 1.00 1.07 1.01 1.06 1.09 .99 1.02
KLA/ATP 1.08 1.06 1.16 1.11 1.16 1.12 1.04
Mm.57127
KLA  ATP  ATP+KLA
117168292 Unknown KLA 1.20 1.25 1.28 1.18 1.14 1.13 1.12
ATP .98 .95 1.11 1.06 1.05 1.05 1.09
KLA/ATP 1.22 1.24 1.48 1.55 1.40 1.21 1.07
Nfkb1
KLA  ATP  ATP+KLA
BC050841 nuclear factor of kappa light chain gene enhancer in B-cells 1, p105, mRNA (cDNA clone IMAGE:6392793), complete cds. [BC050841] KLA 5.81 4.96 4.77 3.21 3.37 2.00 1.71
ATP 1.39 1.52 3.25 12.63 13.64 4.80 1.08
KLA/ATP 7.21 8.69 19.53 23.93 11.70 2.85 2.01
Nfkb1
KLA  ATP  ATP+KLA
M57999 gb|Mouse transcription factor NF-kappa-B DNA binding subunit mRNA, complete cds. [M57999] KLA 8.55 7.87 7.35 6.13 3.51 1.85 1.38
ATP .98 .96 1.21 3.06 5.29 4.67 .69
KLA/ATP 7.32 7.20 8.71 10.82 5.55 2.77 1.54
Nfkbia
KLA  ATP  ATP+KLA
NM_010907 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (Nfkbia), mRNA [NM_010907] KLA 18.65 18.46 13.63 17.88 14.25 9.17 7.92
ATP .91 1.09 7.11 32.39 17.44 10.49 1.72
KLA/ATP 15.57 17.66 15.73 23.91 13.83 10.73 9.48
Nfkbib
KLA  ATP  ATP+KLA
NM_010908 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta (Nfkbib), mRNA [NM_010908] KLA 4.63 4.69 4.36 4.27 4.23 2.52 2.17
ATP 1.11 1.22 1.55 4.23 4.93 3.66 1.76
KLA/ATP 4.71 5.41 4.58 7.08 6.20 4.73 4.11
Polr2e
KLA  ATP  ATP+KLA
AK010567 ES cells cDNA, RIKEN full-length enriched library, clone:2410021N14 product:polymerase (RNA) II (DNA directed) polypeptide E, full insert sequence. [AK010567] KLA .67 .68 .68 .56 .58 .45 .67
ATP 1.14 1.18 1.05 1.26 .91 .63 .80
KLA/ATP .80 .77 .71 .81 .75 .50 .49
Polr2e
KLA  ATP  ATP+KLA
NM_025554 polymerase (RNA) II (DNA directed) polypeptide E (Polr2e), mRNA [NM_025554] KLA .69 .74 .69 .61 .56 .49 .70
ATP 1.00 1.06 1.02 1.20 .88 .67 .73
KLA/ATP .79 .76 .72 .80 .77 .55 .45
Polr2f
KLA  ATP  ATP+KLA
NM_027231 polymerase (RNA) II (DNA directed) polypeptide F (Polr2f), mRNA [NM_027231] KLA 1.01 .99 .92 .94 .86 .78 .84
ATP .94 1.00 1.18 1.34 1.14 .88 .91
KLA/ATP .96 1.07 1.23 1.38 1.16 .96 .70
Polr2h
KLA  ATP  ATP+KLA
NM_145632 polymerase (RNA) II (DNA directed) polypeptide H (Polr2h), mRNA [NM_145632] KLA .80 .76 .66 .62 .73 .87 1.14
ATP .90 .91 1.01 .99 1.10 1.32 .98
KLA/ATP .68 .72 .69 .65 .90 1.01 .62
Polr2l
KLA  ATP  ATP+KLA
XM_888022 gb|PREDICTED: Mus musculus polymerase (RNA) II (DNA directed) polypeptide L (Polr2l), mRNA [XM_888022] KLA .82 .92 .85 .82 .77 .73 .88
ATP .95 1.00 1.15 1.42 1.20 .91 .99
KLA/ATP .86 .89 1.04 1.23 1.25 .91 .59
Polr3a
KLA  ATP  ATP+KLA
AK039440 adult male spinal cord cDNA, RIKEN full-length enriched library, clone:A330043C08 product:hypothetical protein, full insert sequence. [AK039440] KLA 1.02 .94 .96 .97 1.13 .97 1.02
ATP .71 .55 .59 .69 .88 .93 .94
KLA/ATP .81 .65 .65 .80 .83 .88 .75
Polr3a
KLA  ATP  ATP+KLA
NM_001081247 polymerase (RNA) III (DNA directed) polypeptide A (Polr3a), mRNA [NM_001081247] KLA 1.16 1.20 1.27 1.15 1.26 1.17 1.32
ATP .98 1.08 1.07 .92 .80 .99 1.26
KLA/ATP 1.22 1.30 1.18 .99 .78 1.24 1.27
Polr3b
KLA  ATP  ATP+KLA
NM_027423 polymerase (RNA) III (DNA directed) polypeptide B (Polr3b), mRNA [NM_027423] KLA 1.03 1.05 1.02 1.07 1.11 1.15 1.05
ATP 1.09 1.15 .96 .97 .73 .75 .93
KLA/ATP 1.04 1.12 1.00 1.00 .74 .75 .77
Polr3c
KLA  ATP  ATP+KLA
XM_131049 gb|PREDICTED: Mus musculus polymerase (RNA) III (DNA directed) polypeptide C, transcript variant 1 (Polr3c), mRNA [XM_131049] KLA 2.33 2.34 2.59 2.37 2.10 1.82 1.42
ATP 1.02 .97 1.12 1.19 .99 1.10 1.14
KLA/ATP 2.34 2.54 2.70 2.54 2.18 1.75 1.88
Polr3d
KLA  ATP  ATP+KLA
NM_025945 polymerase (RNA) III (DNA directed) polypeptide D (Polr3d), mRNA [NM_025945] KLA 1.08 1.08 .90 .88 .98 .99 1.60
ATP .95 1.00 .94 .89 1.23 1.19 1.21
KLA/ATP 1.06 1.13 .88 .82 .68 .72 .55
Polr3e
KLA  ATP  ATP+KLA
AK162059 adult male adrenal gland cDNA, RIKEN full-length enriched library, clone:7330401M11 product:sex-lethal interactor homolog (Drosophila), full insert sequence [AK162059] KLA .48 .46 .37 .33 .47 .53 .72
ATP 1.06 .96 .57 .49 .65 .27 .29
KLA/ATP .54 .43 .28 .37 .44 .27 .18
Polr3e
KLA  ATP  ATP+KLA
NM_025298 polymerase (RNA) III (DNA directed) polypeptide E (Polr3e), mRNA [NM_025298] KLA .66 .69 .61 .58 .65 .72 1.37
ATP 1.01 .95 .80 .74 .58 .58 1.01
KLA/ATP .71 .69 .52 .57 .46 .42 .49
Polr3f
KLA  ATP  ATP+KLA
NM_029763 polymerase (RNA) III (DNA directed) polypeptide F (Polr3f), mRNA [NM_029763] KLA 1.10 1.09 1.09 .98 .95 1.00 1.08
ATP 1.07 1.06 .84 .69 .72 .94 1.06
KLA/ATP 1.13 1.08 .80 .71 .70 .92 .92
Polr3g
KLA  ATP  ATP+KLA
NM_001081176 polymerase (RNA) III (DNA directed) polypeptide G (Polr3g), mRNA [NM_001081176] KLA .51 .53 .43 .45 .41 .45 .57
ATP .90 .84 .68 .55 .54 .64 .60
KLA/ATP .51 .47 .46 .50 .48 .53 .46
Polr3gl
KLA  ATP  ATP+KLA
NM_027241 polymerase (RNA) III (DNA directed) polypeptide G like (Polr3gl), mRNA [NM_027241] KLA .60 .51 .54 .55 .57 .70 .53
ATP .99 .86 1.08 .84 .48 .57 .69
KLA/ATP .55 .49 .64 .50 .53 .57 .67
Polr3h
KLA  ATP  ATP+KLA
NM_030229 polymerase (RNA) III (DNA directed) polypeptide H (Polr3h), mRNA [NM_030229] KLA .89 .85 .75 .81 .76 .85 1.01
ATP .93 .81 .86 .71 .70 .93 .83
KLA/ATP .75 .78 .73 .70 .69 .76 .76
Polr3k
KLA  ATP  ATP+KLA
NM_025901 polymerase (RNA) III (DNA directed) polypeptide K (Polr3k), mRNA [NM_025901] KLA .72 .72 .66 .69 .63 .74 .85
ATP .87 .84 1.14 .92 .64 .87 .72
KLA/ATP .65 .71 .90 .74 .65 .53 .44
Pycard
KLA  ATP  ATP+KLA
NM_023258 PYD and CARD domain containing (Pycard), mRNA [NM_023258] KLA 1.48 1.44 1.62 1.81 1.80 1.69 .94
ATP .89 .88 1.00 .84 .52 .30 .62
KLA/ATP 1.32 1.34 1.65 1.38 1.14 .50 .41
Rela
KLA  ATP  ATP+KLA
NM_009045 v-rel reticuloendotheliosis viral oncogene homolog A (avian) (Rela), mRNA [NM_009045] KLA 2.05 2.05 2.07 1.75 1.83 1.58 1.33
ATP 1.03 1.08 1.10 1.44 1.61 2.48 1.05
KLA/ATP 2.17 2.27 2.05 2.47 1.93 2.35 2.02
Ripk1
KLA  ATP  ATP+KLA
NM_009068 receptor (TNFRSF)-interacting serine-threonine kinase 1 (Ripk1), mRNA [NM_009068] KLA 1.32 1.33 1.50 1.09 1.00 1.11 1.13
ATP .98 .94 .60 .59 1.35 1.56 1.45
KLA/ATP 1.48 1.30 1.01 1.05 1.36 1.53 1.37
Ripk3
KLA  ATP  ATP+KLA
NM_019955 receptor-interacting serine-threonine kinase 3 (Ripk3), mRNA [NM_019955] KLA .71 .68 .69 .70 .66 .67 .74
ATP 1.11 1.03 1.10 1.29 1.75 2.12 2.29
KLA/ATP .77 .73 .72 .78 1.67 2.43 3.60
Rpo1-1
KLA  ATP  ATP+KLA
NM_009085 RNA polymerase 1-1 (Rpo1-1), mRNA [NM_009085] KLA .77 .81 .81 .91 .90 .68 .86
ATP 1.03 .92 .86 .94 2.06 1.70 .91
KLA/ATP .82 .85 .86 .65 1.41 1.49 .92
Rpo1-3
KLA  ATP  ATP+KLA
NM_009087 RNA polymerase 1-3 (Rpo1-3), transcript variant 1, mRNA [NM_009087] KLA 1.00 .98 .86 .90 .95 .76 .93
ATP 1.07 1.09 1.20 1.26 1.26 1.12 .99
KLA/ATP .89 1.04 1.10 1.08 1.01 .71 .67
Rpo1-3
KLA  ATP  ATP+KLA
NM_181730 RNA polymerase 1-3 (Rpo1-3), transcript variant 2, mRNA [NM_181730] KLA 1.06 1.17 1.07 1.08 .99 1.04 .98
ATP .93 .97 1.12 1.27 1.36 1.31 .82
KLA/ATP 1.02 1.06 1.20 1.31 1.28 1.32 .90
Tbk1
KLA  ATP  ATP+KLA
NM_019786 TANK-binding kinase 1 (Tbk1), mRNA [NM_019786] KLA 2.55 2.76 3.22 2.67 2.56 2.29 1.96
ATP 1.13 1.30 1.12 1.07 1.29 1.41 1.40
KLA/ATP 2.84 3.17 2.58 2.43 1.70 2.15 2.37
Tmem173
KLA  ATP  ATP+KLA
XM_900126 gb|PREDICTED: Mus musculus RIKEN cDNA 2610307O08 gene, transcript variant 5 (2610307O08Rik), mRNA [XM_900126] KLA 1.39 1.28 1.52 1.40 1.12 .69 .64
ATP 1.10 .92 1.09 .89 .76 .67 .90
KLA/ATP 1.39 1.43 2.00 1.59 1.56 .94 .90
Trex1
KLA  ATP  ATP+KLA
NM_011637 three prime repair exonuclease 1 (Trex1), transcript variant 1, mRNA [NM_011637] KLA 5.71 5.62 5.82 5.30 6.20 6.50 6.28
ATP .91 .81 .61 .87 1.41 4.22 4.28
KLA/ATP 5.98 5.51 3.77 6.37 6.71 8.77 15.05
Zbp1
KLA  ATP  ATP+KLA
NM_021394 Z-DNA binding protein 1 (Zbp1), mRNA [NM_021394] KLA 10.24 8.57 7.83 9.86 8.81 8.33 8.12
ATP 1.09 .89 1.18 1.00 .91 4.20 7.64
KLA/ATP 8.73 8.97 12.12 11.36 12.58 10.55 12.63