Microarray analysis of bone marrow-derived macrophage cells treated with Kdo2-lipid A (KLA) and ATP

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Kdo2-Lipid A / ATP gene array data - treatment:control ratios

KEGG pathway: Bacterial invasion of epithelial cells (mmu05100)

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Gene symbol    Time course plot Accession Description Treatment 15min 30min 1hr 2hr 4hr 8hr 20hr
11-Sep
KLA  ATP  ATP+KLA
 AK028475 0 day neonate skin cDNA, RIKEN full-length enriched library, clone:4631422A03 product:similar to SEPTIN6 TYPE II [Homo sapiens], full insert sequence. [AK028475] KLA 4.36 4.39 3.55 3.57 1.67 .45 .45
ATP .89 .81 1.14 .94 4.31 7.32 .62
KLA/ATP 3.57 4.39 4.64 3.59 3.47 2.03 .26
12-Sep
KLA  ATP  ATP+KLA
 AK077091 adult male testis cDNA, RIKEN full-length enriched library, clone:4933403B13 product:weakly similar to OVARIAN [AK077091] KLA 1.05 1.00 1.01 .96 .97 1.04 .98
ATP .96 1.02 1.05 .98 .94 .96 .97
KLA/ATP .98 .98 .98 1.04 .98 .90 .98
12-Sep
KLA  ATP  ATP+KLA
 NM_027669 septin 12 (Sept12), mRNA [NM_027669] KLA .97 1.02 1.05 1.01 1.13 1.03 .94
ATP 1.00 1.08 .92 1.05 1.02 .90 .94
KLA/ATP .99 1.07 1.09 .97 .96 .99 .95
2-Sep
KLA  ATP  ATP+KLA
 NM_010891 septin 2 (Sept2), mRNA [NM_010891] KLA 1.22 1.32 1.26 1.30 1.13 .94 1.04
ATP 1.01 1.08 1.11 1.09 .91 .80 1.14
KLA/ATP 1.28 1.36 1.31 1.33 .96 .71 .96
3-Sep
KLA  ATP  ATP+KLA
 NM_011889 septin 3 (Sept3), mRNA [NM_011889] KLA .95 .98 .94 .99 .97 1.00 .96
ATP 1.02 1.05 1.01 1.01 1.04 1.02 1.03
KLA/ATP .92 .95 .98 1.03 .95 1.02 1.01
4631416L
12Rik
KLA  ATP  ATP+KLA
 AK087060 0 day neonate lung cDNA, RIKEN full-length enriched library, clone:E030024E19 product:weakly similar to PUTATIVE SH3 DOMAIN-CONTAINING GUANINE EXCHANGE FACTOR SGEF [Homo sapiens], full insert sequence. [AK087060] KLA .99 1.02 .97 .99 .94 1.05 .94
ATP .90 1.08 1.01 1.01 .98 .98 .98
KLA/ATP 1.01 .94 .99 .98 .98 .94 1.03
4631416L
12Rik
KLA  ATP  ATP+KLA
 NM_001081295 RIKEN cDNA 4631416L12 gene (4631416L12Rik), mRNA [NM_001081295] KLA 1.09 1.04 .99 1.05 1.04 .88 1.02
ATP 1.02 .98 .93 .98 .98 .90 .98
KLA/ATP 1.00 1.01 .98 .98 .95 .96 .98
6-Sep
KLA  ATP  ATP+KLA
 AK172894 mRNA for mKIAA0128 protein [AK172894] KLA 1.07 1.04 1.05 1.02 .90 .60 .53
ATP 1.13 1.15 1.19 1.34 1.14 .68 .56
KLA/ATP 1.17 1.13 1.16 1.15 .85 .58 .34
6-Sep
KLA  ATP  ATP+KLA
 NM_019942 septin 6 (Sept6), mRNA [NM_019942] KLA .88 .93 .96 .91 .80 .61 .61
ATP 1.14 1.21 1.33 1.57 1.20 .87 .60
KLA/ATP 1.03 1.12 .95 1.10 .82 .69 .46
8-Sep
KLA  ATP  ATP+KLA
 NM_033144 septin 8 (Sept8), mRNA [NM_033144] KLA .48 .41 .41 .44 .55 .84 .86
ATP 1.05 .89 .89 .48 .53 .71 1.04
KLA/ATP .40 .39 .50 .30 .41 .38 .78
9-Sep
KLA  ATP  ATP+KLA
 NM_017380 septin 9 (Sept9), transcript variant 4, mRNA [NM_017380] KLA .52 .55 .46 .38 .34 .46 .72
ATP 1.15 1.19 .94 1.12 .86 .48 .70
KLA/ATP .60 .58 .38 .44 .48 .43 .45
AK044953
KLA  ATP  ATP+KLA
 AK044953 9.5 days embryo parthenogenote cDNA, RIKEN full-length enriched library, clone:B130015K01 product:unclassifiable, full insert sequence. [AK044953] KLA .54 .53 .47 .57 .61 .59 .60
ATP 1.02 .94 1.06 .95 .53 .55 .73
KLA/ATP .54 .47 .60 .67 .66 .49 .50
Actb
KLA  ATP  ATP+KLA
 BC016624 cDNA clone IMAGE:4501052 [BC016624] KLA 1.20 1.20 1.19 1.73 1.83 2.52 1.70
ATP 1.04 1.01 1.03 .92 1.07 .66 .91
KLA/ATP 1.34 1.40 1.69 1.28 1.27 1.19 1.06
Actb
KLA  ATP  ATP+KLA
 NM_007393 actin, beta, cytoplasmic (Actb), mRNA [NM_007393] KLA 1.58 1.64 1.59 2.02 2.03 3.04 1.75
ATP 1.00 .95 1.26 1.18 1.33 .86 .91
KLA/ATP 1.52 1.75 2.42 1.92 2.17 1.54 1.28
Actg1
KLA  ATP  ATP+KLA
 NM_009609 actin, gamma, cytoplasmic 1 (Actg1), mRNA [NM_009609] KLA 1.02 1.03 1.34 1.07 1.49 1.58 .71
ATP 1.07 1.24 .76 .76 .63 .46 .78
KLA/ATP 1.20 1.30 .75 .82 .60 .53 .55
Arhgap10
KLA  ATP  ATP+KLA
 NM_030113 Rho GTPase activating protein 10 (Arhgap10), mRNA [NM_030113] KLA 1.07 .95 .90 .82 .95 1.40 1.42
ATP 1.19 1.26 1.11 1.47 1.36 .86 1.55
KLA/ATP 1.15 1.08 .90 1.10 1.01 .92 1.88
Arpc1a
KLA  ATP  ATP+KLA
 NM_019767 actin related protein 2/3 complex, subunit 1A (Arpc1a), mRNA [NM_019767] KLA .80 .78 .73 .79 .90 1.02 .97
ATP 1.01 1.07 .93 .86 .83 1.14 1.15
KLA/ATP .77 .74 .64 .64 .77 1.13 1.51
Arpc1b
KLA  ATP  ATP+KLA
 NM_023142 actin related protein 2/3 complex, subunit 1B (Arpc1b), mRNA [NM_023142] KLA .85 .86 .81 .83 .92 .93 1.03
ATP 1.03 .98 .86 .79 .84 .85 .91
KLA/ATP .88 .84 .83 .73 .71 .70 .63
Arpc2
KLA  ATP  ATP+KLA
 NM_029711 actin related protein 2/3 complex, subunit 2 (Arpc2), mRNA [NM_029711] KLA .88 .89 1.05 .92 1.18 1.31 1.21
ATP 1.20 1.18 .86 .94 .85 .48 .87
KLA/ATP 1.04 1.05 .78 .87 .70 .60 .92
Arpc3
KLA  ATP  ATP+KLA
 NM_019824 actin related protein 2/3 complex, subunit 3 (Arpc3), mRNA [NM_019824] KLA .93 .96 1.05 .95 1.07 1.09 .80
ATP 1.08 1.05 .95 .99 1.03 1.01 .97
KLA/ATP 1.00 1.02 .99 1.04 1.06 1.21 .99
Arpc4
KLA  ATP  ATP+KLA
 NM_026552 actin related protein 2/3 complex, subunit 4 (Arpc4), mRNA [NM_026552] KLA .75 .81 .83 .73 .94 1.12 1.12
ATP 1.09 1.34 .90 1.52 .98 .63 .89
KLA/ATP .92 .90 .58 1.10 .64 .69 .87
Arpc5
KLA  ATP  ATP+KLA
 NM_026369 actin related protein 2/3 complex, subunit 5 (Arpc5), mRNA [NM_026369] KLA 1.35 1.37 1.44 1.33 1.59 1.84 1.39
ATP .98 1.08 1.01 1.14 .97 .87 1.36
KLA/ATP 1.19 1.30 1.23 1.44 1.13 1.28 1.60
Arpc5l
KLA  ATP  ATP+KLA
 NM_028809 actin related protein 2/3 complex, subunit 5-like (Arpc5l), mRNA [NM_028809] KLA .59 .61 .60 .59 .61 .77 1.02
ATP .92 .92 .99 1.01 .79 .76 1.01
KLA/ATP .58 .60 .64 .59 .66 .71 .98
BC010335
KLA  ATP  ATP+KLA
 BC010335 fibronectin 1, mRNA (cDNA clone IMAGE:3156499), **** WARNING: chimeric clone ****. [BC010335] KLA .94 .88 1.01 .99 .95 .95 1.07
ATP 1.06 .98 1.20 1.30 1.07 .97 .97
KLA/ATP .93 1.00 1.07 1.20 1.02 .96 .94
Bcar1
KLA  ATP  ATP+KLA
 NM_009954 breast cancer anti-estrogen resistance 1 (Bcar1), mRNA [NM_009954] KLA .88 .87 .82 .88 1.06 1.12 1.70
ATP 1.04 1.05 1.00 1.27 1.34 1.62 1.34
KLA/ATP .95 .87 .87 .95 1.02 1.17 2.10
Cav1
KLA  ATP  ATP+KLA
 NM_007616 caveolin, caveolae protein 1 (Cav1), mRNA [NM_007616] KLA 14.41 13.85 11.14 10.72 9.47 4.26 1.52
ATP 1.05 1.13 1.37 1.72 3.27 15.82 13.01
KLA/ATP 12.62 15.59 16.15 16.68 11.37 8.19 14.27
Cav2
KLA  ATP  ATP+KLA
 NM_016900 caveolin 2 (Cav2), mRNA [NM_016900] KLA 1.04 1.01 .95 .81 .55 .29 .40
ATP 1.08 1.17 1.18 1.18 1.02 .93 .74
KLA/ATP 1.04 1.08 .96 1.13 .62 .28 .57
Cav3
KLA  ATP  ATP+KLA
 NM_007617 caveolin 3 (Cav3), mRNA [NM_007617] KLA 1.01 1.05 1.01 1.08 .97 1.04 1.07
ATP 1.00 1.00 1.03 1.08 1.02 1.08 .98
KLA/ATP 1.05 .98 .83 1.14 1.09 1.10 1.00
Cbl
KLA  ATP  ATP+KLA
 NM_007619 Casitas B-lineage lymphoma (Cbl), mRNA [NM_007619] KLA 1.23 1.22 1.54 1.84 2.25 2.58 2.75
ATP 1.04 1.12 1.07 1.53 1.55 2.12 3.23
KLA/ATP 1.23 1.20 1.22 1.44 1.31 1.88 6.28
Cblb
KLA  ATP  ATP+KLA
 AK045005 9.5 days embryo parthenogenote cDNA, RIKEN full-length enriched library, clone:B130018P07 product:hypothetical protein, full insert sequence. [AK045005] KLA 1.16 1.11 1.15 1.10 1.16 .98 .93
ATP 1.16 1.23 .98 1.28 1.34 .73 1.55
KLA/ATP 1.26 1.60 1.64 1.23 1.01 .91 1.05
Cblb
KLA  ATP  ATP+KLA
 AK084162 12 days embryo eyeball cDNA, RIKEN full-length enriched library, clone:D230004I05 product:unclassifiable, full insert sequence. [AK084162] KLA .97 .98 1.02 1.01 .84 1.02 1.03
ATP 1.03 1.02 .98 1.09 1.05 .96 .96
KLA/ATP 1.07 .95 .91 .98 .98 1.01 1.00
Cblc
KLA  ATP  ATP+KLA
 NM_023224 Casitas B-lineage lymphoma c (Cblc), mRNA [NM_023224] KLA 1.02 .98 1.01 1.02 1.00 .99 1.05
ATP .94 .95 .97 1.04 .99 .97 .99
KLA/ATP 1.00 1.01 .96 .97 .94 .92 .99
Cd2ap
KLA  ATP  ATP+KLA
 NM_009847 CD2-associated protein (Cd2ap), mRNA [NM_009847] KLA 3.29 3.37 3.71 4.30 3.29 2.16 2.00
ATP 1.10 1.11 1.12 .88 .75 .86 .94
KLA/ATP 3.53 3.48 3.87 2.80 1.63 1.01 1.14
Cdc42
KLA  ATP  ATP+KLA
 NM_009861 cell division cycle 42 homolog (S. cerevisiae) (Cdc42), mRNA [NM_009861] KLA 1.04 1.01 1.02 1.04 1.12 1.21 1.12
ATP 1.07 1.10 1.04 1.06 1.02 .95 1.14
KLA/ATP .94 1.04 1.01 .97 .95 1.02 1.25
Cdh1
KLA  ATP  ATP+KLA
 NM_009864 cadherin 1 (Cdh1), mRNA [NM_009864] KLA 1.03 1.03 .99 .94 .95 .97 .99
ATP 1.04 1.06 1.06 .96 .99 1.07 .95
KLA/ATP 1.02 1.07 1.00 .90 .93 .94 .98
Clta
KLA  ATP  ATP+KLA
 AK035903 16 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:9630016K07 product:unclassifiable, full insert sequence [AK035903] KLA 1.01 1.00 .97 1.02 1.01 1.12 1.09
ATP 1.04 .98 .91 1.05 1.02 1.01 .95
KLA/ATP 1.00 .99 .93 1.07 1.09 .98 .99
Clta
KLA  ATP  ATP+KLA
 NM_016760 clathrin, light polypeptide (Lca) (Clta), transcript variant 3, mRNA [NM_016760] KLA .68 .70 .75 .68 .70 .77 .55
ATP 1.06 1.05 .93 .97 .81 .60 .75
KLA/ATP .75 .76 .68 .71 .69 .64 .42
Cltb
KLA  ATP  ATP+KLA
 NM_028870 clathrin, light polypeptide (Lcb) (Cltb), mRNA [NM_028870] KLA .91 1.01 .97 .78 .71 .52 .73
ATP 1.15 1.32 1.07 1.72 1.96 1.94 1.31
KLA/ATP 1.07 1.17 .76 1.17 1.18 2.12 1.06
Cltc
KLA  ATP  ATP+KLA
 AK039453 adult male spinal cord cDNA, RIKEN full-length enriched library, clone:A330045B10 product:CLATHRIN HEAVY CHAIN 1 (CLH-17) homolog [Homo sapiens], full insert sequence. [AK039453] KLA 1.07 1.00 1.01 1.00 1.03 1.06 1.02
ATP 1.00 .99 1.02 .97 1.00 1.02 1.00
KLA/ATP 1.01 1.01 1.02 .98 1.04 .98 .99
Cltc
KLA  ATP  ATP+KLA
 NM_001003908 clathrin, heavy polypeptide (Hc) (Cltc), mRNA [NM_001003908] KLA .94 1.00 .98 .89 1.18 1.02 .93
ATP 1.21 1.42 .72 .89 .93 .96 .75
KLA/ATP 1.12 1.21 .48 .72 .57 .87 .81
Crk
KLA  ATP  ATP+KLA
 NM_133656 v-crk sarcoma virus CT10 oncogene homolog (avian) (Crk), mRNA [NM_133656] KLA 1.29 1.32 1.41 1.38 1.75 1.59 1.52
ATP 1.08 1.17 1.01 .93 1.27 2.11 1.70
KLA/ATP 1.37 1.49 1.14 1.09 1.21 1.69 2.32
Crkl
KLA  ATP  ATP+KLA
 NM_007764 v-crk sarcoma virus CT10 oncogene homolog (avian)-like (Crkl), mRNA [NM_007764] KLA 1.85 1.97 2.08 1.73 1.66 1.64 1.36
ATP .97 .94 .78 .74 1.46 1.89 1.46
KLA/ATP 1.92 1.88 1.18 1.44 1.67 2.65 2.72
Ctnna1
KLA  ATP  ATP+KLA
 AK008121 adult male small intestine cDNA, RIKEN full-length enriched library, clone:2010005H04 product:unclassifiable, full insert sequence. [AK008121] KLA .82 .76 .72 .81 .94 .74 .80
ATP 1.08 1.01 .51 .57 2.45 1.25 .95
KLA/ATP .91 .82 .76 .58 1.58 1.01 .92
Ctnna1
KLA  ATP  ATP+KLA
 NM_009818 catenin (cadherin associated protein), alpha 1 (Ctnna1), mRNA [NM_009818] KLA .97 .91 1.06 .84 .75 .52 .56
ATP 1.09 1.14 1.00 .86 .80 .98 .83
KLA/ATP 1.02 1.07 .90 .80 .66 .59 .57
Ctnna2
KLA  ATP  ATP+KLA
 AK035033 12 days embryo embryonic body between diaphragm region and neck cDNA, RIKEN full-length enriched library, clone:9430076K22 product:hypothetical Vinculin and alpha-catenin containing protein, full insert sequence [AK035033] KLA 1.05 1.11 1.12 1.05 1.02 1.04 1.19
ATP .99 .97 1.00 1.05 1.02 1.05 1.03
KLA/ATP 1.11 1.06 1.01 1.12 1.06 1.02 1.03
Ctnna3
KLA  ATP  ATP+KLA
 AK029664 adult male testis cDNA, RIKEN full-length enriched library, clone:4930438F12 product:unclassifiable, full insert sequence. [AK029664] KLA 1.03 1.06 .99 1.05 .95 1.01 1.04
ATP 1.03 1.05 1.02 1.04 .99 1.03 1.05
KLA/ATP 1.01 1.00 .99 1.01 1.00 .98 1.05
Ctnna3
KLA  ATP  ATP+KLA
 NM_177612 catenin (cadherin associated protein), alpha 3 (Ctnna3), mRNA [NM_177612] KLA 1.01 1.06 .98 1.04 1.03 1.04 1.07
ATP .96 1.02 .94 1.11 1.02 1.09 .91
KLA/ATP 1.01 .94 .94 1.10 1.10 1.04 1.04
Ctnnb1
KLA  ATP  ATP+KLA
 AK020013 adult male thymus cDNA, RIKEN full-length enriched library, clone:5830416C23 product:catenin beta, full insert sequence. [AK020013] KLA 1.06 1.15 1.00 1.06 1.27 1.14 1.03
ATP .85 .57 1.74 3.36 4.13 2.19 1.55
KLA/ATP 1.12 .87 2.47 3.61 3.79 2.21 2.06
Ctnnb1
KLA  ATP  ATP+KLA
 NM_007614 catenin (cadherin associated protein), beta 1 (Ctnnb1), mRNA [NM_007614] KLA 1.02 1.07 1.13 1.03 1.04 .93 .96
ATP 1.12 1.14 .75 .77 .73 .72 1.52
KLA/ATP 1.18 1.17 .77 .85 .60 .59 1.35
Cttn
KLA  ATP  ATP+KLA
 NM_007803 cortactin (Cttn), mRNA [NM_007803] KLA 1.12 1.14 1.28 1.32 1.64 2.25 2.00
ATP 1.04 1.02 .98 1.03 1.02 1.21 1.50
KLA/ATP 1.14 1.20 1.09 1.19 1.15 1.54 2.16
Dnm1
KLA  ATP  ATP+KLA
 NM_010065 dynamin 1 (Dnm1), mRNA [NM_010065] KLA .96 .92 .87 .88 .85 .79 1.16
ATP 1.05 1.08 .96 1.04 .93 .80 1.59
KLA/ATP .99 1.00 .82 .93 .79 .79 1.24
Dnm2
KLA  ATP  ATP+KLA
 NM_001039520 dynamin 2 (Dnm2), mRNA [NM_001039520] KLA 1.00 1.03 1.14 1.01 1.29 1.47 1.30
ATP 1.11 1.31 .93 1.41 1.04 .90 1.53
KLA/ATP 1.26 1.23 .87 1.41 .86 .98 1.86
Dnm3
KLA  ATP  ATP+KLA
 NM_001038619 dynamin 3 (Dnm3), mRNA [NM_001038619] KLA 1.00 1.01 1.02 1.02 1.03 .96 1.04
ATP 1.05 1.01 .99 .96 1.03 .97 .88
KLA/ATP 1.03 1.05 1.03 .99 .98 1.02 1.03
Dock1
KLA  ATP  ATP+KLA
 AK163853 16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130086K10 product:dedicator of cyto-kinesis 1, full insert sequence. [AK163853] KLA .94 .92 .94 .89 .75 .72 .75
ATP 1.04 1.01 .93 .84 .69 .63 1.16
KLA/ATP .84 .87 .76 .78 .71 .66 .65
Dock1
KLA  ATP  ATP+KLA
 NM_001033420 dedicator of cytokinesis 1 (Dock1), mRNA [NM_001033420] KLA 1.15 .95 .89 .75 .42 .19 .31
ATP 1.01 .83 .45 .41 .30 .17 .37
KLA/ATP .94 .85 .40 .24 .16 .15 .16
Elmo1
KLA  ATP  ATP+KLA
 NM_198093 engulfment and cell motility 1, ced-12 homolog (C. elegans) (Elmo1), transcript variant 2, mRNA [NM_198093] KLA 1.36 1.37 1.16 1.20 1.02 .98 .72
ATP .88 .89 1.14 1.17 1.28 .78 .40
KLA/ATP 1.21 1.21 1.30 1.20 .98 .53 .51
Fn1
KLA  ATP  ATP+KLA
 NM_010233 fibronectin 1 (Fn1), mRNA [NM_010233] KLA 1.23 1.30 1.38 1.12 1.16 1.00 .78
ATP 1.02 1.19 1.25 1.56 1.33 1.05 .95
KLA/ATP 1.36 1.51 1.34 1.70 1.20 1.06 .93
Gab1
KLA  ATP  ATP+KLA
 NM_021356 growth factor receptor bound protein 2-associated protein 1 (Gab1), mRNA [NM_021356] KLA .83 .95 1.12 1.59 3.13 3.14 1.50
ATP .94 .96 1.12 1.74 2.35 5.20 1.66
KLA/ATP .79 .78 1.32 3.74 3.08 4.44 2.62
Hcls1
KLA  ATP  ATP+KLA
 NM_008225 hematopoietic cell specific Lyn substrate 1 (Hcls1), mRNA [NM_008225] KLA 1.40 1.40 1.33 1.57 2.01 2.26 2.51
ATP 1.12 1.08 .92 .87 .83 1.27 1.81
KLA/ATP 1.31 1.48 1.39 1.35 1.05 1.17 3.13
Ilk
KLA  ATP  ATP+KLA
 NM_010562 integrin linked kinase (Ilk), mRNA [NM_010562] KLA .84 .85 .92 .81 .97 .96 .67
ATP 1.03 1.11 .85 1.07 .82 .66 .91
KLA/ATP .93 .90 .58 .94 .63 .63 .80
Itga5
KLA  ATP  ATP+KLA
 NM_010577 integrin alpha 5 (fibronectin receptor alpha) (Itga5), mRNA [NM_010577] KLA 2.63 3.04 2.81 2.47 4.61 5.45 4.90
ATP 1.13 1.62 .74 2.21 1.31 1.93 2.84
KLA/ATP 3.55 3.84 1.15 3.03 1.11 2.81 10.42
Itgb1
KLA  ATP  ATP+KLA
 NM_010578 integrin beta 1 (fibronectin receptor beta) (Itgb1), mRNA [NM_010578] KLA 1.05 1.09 1.13 .92 1.01 .93 .88
ATP 1.14 1.30 .92 1.07 1.04 .83 .70
KLA/ATP 1.26 1.30 .87 1.02 .66 .65 .62
Itgb1
KLA  ATP  ATP+KLA
 U37029 integrin beta1D mRNA, partial cds. [U37029] KLA .93 .95 .96 1.01 .97 1.01 .98
ATP 1.05 .99 .99 1.03 1.03 .97 .94
KLA/ATP .99 .98 1.04 .97 1.02 1.01 .99
Mad2l2
KLA  ATP  ATP+KLA
 NM_027985 MAD2 mitotic arrest deficient-like 2 (yeast) (Mad2l2), mRNA [NM_027985] KLA 1.47 1.43 1.53 1.81 1.64 1.37 1.24
ATP 1.05 .92 1.13 1.24 1.09 1.00 .85
KLA/ATP 1.47 1.50 1.78 1.50 1.75 1.58 1.05
Met
KLA  ATP  ATP+KLA
 NM_008591 met proto-oncogene (Met), mRNA [NM_008591] KLA 3.56 3.71 3.68 3.79 4.24 5.89 6.95
ATP .98 .96 1.16 1.21 3.32 12.98 6.60
KLA/ATP 3.75 3.80 3.58 3.28 3.69 4.27 14.22
Mm.15397
4
KLA  ATP  ATP+KLA
 124486828 Unknown KLA .97 1.09 .93 .93 1.03 1.08 1.10
ATP 1.07 .98 .94 1.04 1.02 1.06 1.12
KLA/ATP .98 1.04 .95 .97 1.03 1.00 1.03
Mm.19309
9
KLA  ATP  ATP+KLA
 46849811 Unknown KLA 1.32 1.36 1.42 1.17 1.06 .90 .58
ATP .98 1.12 1.41 1.81 1.44 1.14 .89
KLA/ATP 1.39 1.55 1.57 2.02 1.43 1.12 .74
Mm.21312
8
KLA  ATP  ATP+KLA
 141801344 Unknown KLA .96 .95 .83 .77 .52 .99 1.32
ATP .80 .82 1.09 .80 .83 1.19 1.46
KLA/ATP .78 .92 .98 .62 .71 .94 1.41
Mm.25381
9
KLA  ATP  ATP+KLA
 118130676 Unknown KLA 1.81 1.88 1.96 1.62 1.89 2.44 1.56
ATP .92 .91 1.24 1.01 1.16 2.06 1.95
KLA/ATP 1.62 1.86 1.86 1.41 1.89 2.37 1.97
Mm.26687
1
KLA  ATP  ATP+KLA
 80978931 Unknown KLA .67 .63 .70 .83 1.66 1.43 1.54
ATP 1.20 1.24 1.22 1.26 1.80 .81 1.02
KLA/ATP .63 .56 .83 1.06 1.26 .70 1.34
Mm.29002
6
KLA  ATP  ATP+KLA
 146141141 Unknown KLA .86 .76 .74 .94 .70 .57 .57
ATP 1.05 .94 1.16 1.33 2.13 2.57 1.15
KLA/ATP .74 .84 1.09 1.07 1.49 2.42 1.05
Mm.34239
2
KLA  ATP  ATP+KLA
 17933765 Unknown KLA 1.15 1.31 1.31 1.04 1.09 1.04 .91
ATP 1.07 1.37 .89 1.59 1.14 .71 .54
KLA/ATP 1.44 1.37 .75 1.45 .66 .56 .68
Mm.37161
0
KLA  ATP  ATP+KLA
 118130576 Unknown KLA .76 .74 .66 .81 .74 1.00 .92
ATP .95 .85 1.03 .71 .79 1.32 1.10
KLA/ATP .69 .70 .67 .53 .84 1.50 1.48
Mm.42857
1
KLA  ATP  ATP+KLA
 57634517 Unknown KLA 2.55 2.37 2.21 2.05 1.63 .76 .46
ATP .91 .91 1.05 .90 1.68 2.43 .78
KLA/ATP 2.12 2.34 2.52 1.75 1.75 .84 .22
Mm.45680
7
KLA  ATP  ATP+KLA
 157951728 Unknown KLA 1.00 1.02 1.05 .97 .99 .96 1.05
ATP 1.13 .98 1.00 1.06 1.02 .94 .98
KLA/ATP 1.11 .96 1.08 1.01 .99 1.01 .98
Mm.81698
KLA  ATP  ATP+KLA
 158937287 Unknown KLA .95 1.02 1.04 .98 1.01 1.04 1.08
ATP 1.00 1.03 .97 1.00 1.03 .98 .96
KLA/ATP 1.07 1.00 .94 .98 1.03 1.05 .97
Pik3ca
KLA  ATP  ATP+KLA
 ENSMUST00000108243 ens|Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K). [Source:Uniprot/SWISSPROT;Acc:P42337] [ENSMUST00000108243] KLA 1.07 1.01 .91 .90 .98 .96 .86
ATP 1.03 .87 1.12 .63 1.22 1.86 .60
KLA/ATP 1.05 .82 .91 .61 1.17 1.26 .63
Pik3ca
KLA  ATP  ATP+KLA
 NM_008839 phosphatidylinositol 3-kinase, catalytic, alpha polypeptide (Pik3ca), mRNA [NM_008839] KLA 1.15 1.11 1.05 .82 .99 1.03 1.27
ATP .98 1.00 .79 .75 .96 1.32 1.10
KLA/ATP 1.10 .98 .64 .72 .80 1.20 1.41
Pik3cb
KLA  ATP  ATP+KLA
 NM_029094 phosphatidylinositol 3-kinase, catalytic, beta polypeptide (Pik3cb), mRNA [NM_029094] KLA 1.06 1.06 1.03 .73 .68 .98 1.69
ATP 1.04 1.21 .95 1.02 .85 .93 1.73
KLA/ATP 1.15 1.27 .73 .83 .58 .81 1.81
Pik3cd
KLA  ATP  ATP+KLA
 NM_008840 phosphatidylinositol 3-kinase catalytic delta polypeptide (Pik3cd), transcript variant 1, mRNA [NM_008840] KLA 2.28 2.42 3.10 4.17 3.35 2.31 1.34
ATP 1.02 .91 .99 .63 .30 .67 .80
KLA/ATP 2.14 2.23 2.70 1.51 1.17 .85 .72
Pik3cd
KLA  ATP  ATP+KLA
 U86587 phosphatidylinositol 3-kinase catalytic subunit p110 delta mRNA, complete cds. [U86587] KLA 2.21 2.24 3.71 3.17 3.67 2.66 1.48
ATP 1.00 1.03 .93 .96 .46 .75 .97
KLA/ATP 2.27 2.32 1.97 2.02 1.01 .99 .98
Pik3cg
KLA  ATP  ATP+KLA
 NM_020272 phosphoinositide-3-kinase, catalytic, gamma polypeptide (Pik3cg), mRNA [NM_020272] KLA .53 .53 .61 .64 .97 .86 .79
ATP 1.01 1.13 .88 .89 .52 .53 .53
KLA/ATP .58 .53 .43 .60 .40 .43 .62
Pik3r1
KLA  ATP  ATP+KLA
 NM_001077495 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) (Pik3r1), transcript variant 2, mRNA [NM_001077495] KLA 1.05 1.07 1.03 1.00 1.01 1.20 .85
ATP .97 1.02 1.48 1.42 1.76 1.33 1.23
KLA/ATP 1.11 1.12 1.06 1.17 1.24 .99 1.12
Pik3r2
KLA  ATP  ATP+KLA
 NM_008841 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta) (Pik3r2), mRNA [NM_008841] KLA .50 .50 .48 .43 .46 .66 .75
ATP .78 .68 .45 .43 .28 .57 1.37
KLA/ATP .49 .38 .32 .33 .38 .67 1.10
Pik3r3
KLA  ATP  ATP+KLA
 NM_181585 phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55) (Pik3r3), mRNA [NM_181585] KLA 1.59 1.49 1.37 1.17 1.05 1.55 1.41
ATP 1.12 1.00 1.33 1.70 2.01 2.37 2.02
KLA/ATP 1.63 1.54 1.58 1.70 2.43 2.68 1.92
Pik3r5
KLA  ATP  ATP+KLA
 NM_177320 phosphoinositide-3-kinase, regulatory subunit 5, p101 (Pik3r5), mRNA [NM_177320] KLA 3.57 3.58 4.16 3.54 4.11 2.59 2.39
ATP 1.08 1.08 .93 1.67 3.11 1.88 1.34
KLA/ATP 3.91 3.70 3.30 3.80 2.70 2.04 3.00
Ptk2
KLA  ATP  ATP+KLA
 NM_007982 PTK2 protein tyrosine kinase 2 (Ptk2), mRNA [NM_007982] KLA .99 .99 1.02 1.04 1.09 1.22 1.57
ATP 1.04 1.09 .95 .98 .67 .96 .87
KLA/ATP .99 1.03 .87 .93 .81 1.16 1.04
Pxn
KLA  ATP  ATP+KLA
 AK084243 12 days embryo eyeball cDNA, RIKEN full-length enriched library, clone:D230012N01 product:inferred: paxillin beta {Homo sapiens}, full insert sequence. [AK084243] KLA 1.06 .92 1.01 .95 .97 .97 1.02
ATP 1.02 1.02 .97 .90 .98 .94 .89
KLA/ATP .96 .97 .98 .91 1.01 1.00 .94
Pxn
KLA  ATP  ATP+KLA
 NM_133915 paxillin (Pxn), transcript variant beta, mRNA [NM_133915] KLA 1.13 1.13 1.14 1.14 1.49 1.60 1.30
ATP 1.11 1.22 .86 1.04 1.14 1.18 1.35
KLA/ATP 1.41 1.22 .80 .92 1.07 1.54 2.60
Rac1
KLA  ATP  ATP+KLA
 NM_009007 RAS-related C3 botulinum substrate 1 (Rac1), mRNA [NM_009007] KLA 1.02 1.01 1.02 .99 1.03 1.15 1.08
ATP .99 1.15 1.01 1.27 1.06 1.20 1.06
KLA/ATP 1.00 1.04 .88 1.16 .91 1.21 1.38
Rhoa
KLA  ATP  ATP+KLA
 NM_016802 ras homolog gene family, member A (Rhoa), mRNA [NM_016802] KLA .93 1.00 1.07 .97 1.08 1.06 1.02
ATP .93 .88 .49 .61 .63 .78 1.05
KLA/ATP .94 .92 .59 .63 .61 .78 1.12
Rhog
KLA  ATP  ATP+KLA
 NM_019566 ras homolog gene family, member G (Rhog), mRNA [NM_019566] KLA 1.57 1.55 1.66 1.83 2.33 1.91 2.00
ATP 1.26 1.37 .78 1.26 1.18 1.68 1.74
KLA/ATP 1.96 2.13 1.20 1.98 1.11 1.62 3.39
Shc1
KLA  ATP  ATP+KLA
 NM_011368 src homology 2 domain-containing transforming protein C1 (Shc1), transcript variant 2, mRNA [NM_011368] KLA .88 .87 .86 .83 1.09 1.11 1.12
ATP 1.04 1.25 .85 1.17 .93 1.16 1.00
KLA/ATP .93 .96 .62 .96 .75 1.25 1.19
Shc2
KLA  ATP  ATP+KLA
 NM_001024539 src homology 2 domain-containing transforming protein C2 (Shc2), mRNA [NM_001024539] KLA 1.19 1.25 1.22 1.16 1.15 1.14 .98
ATP 1.04 1.14 1.15 1.53 1.29 1.06 1.09
KLA/ATP 1.26 1.24 1.26 1.49 1.31 1.30 1.30
Shc3
KLA  ATP  ATP+KLA
 NM_009167 src homology 2 domain-containing transforming protein C3 (Shc3), mRNA [NM_009167] KLA 1.00 .98 1.06 1.06 1.12 1.08 1.04
ATP .99 1.02 1.00 1.05 1.00 1.08 1.08
KLA/ATP 1.08 1.06 1.01 1.06 1.03 1.12 1.41
Shc4
KLA  ATP  ATP+KLA
 NM_199022 SHC (Src homology 2 domain containing) family, member 4 (Shc4), mRNA [NM_199022] KLA 1.03 1.03 1.01 1.06 1.09 1.03 1.06
ATP .99 1.00 1.03 1.02 1.04 1.04 1.01
KLA/ATP .98 .97 1.06 1.05 1.00 1.00 1.14
Src
KLA  ATP  ATP+KLA
 NM_009271 Rous sarcoma oncogene (Src), transcript variant 1, mRNA [NM_009271] KLA 6.99 7.23 7.54 5.99 5.34 3.39 3.00
ATP 1.02 1.06 1.06 2.08 4.41 5.03 3.97
KLA/ATP 7.44 7.51 5.48 6.24 4.86 5.86 7.90
Vcl
KLA  ATP  ATP+KLA
 NM_009502 vinculin (Vcl), mRNA [NM_009502] KLA .88 .97 .87 .70 .73 .69 .70
ATP 1.07 1.25 1.00 1.24 .87 1.17 1.17
KLA/ATP .98 1.02 .72 .98 .58 .71 .88
Was
KLA  ATP  ATP+KLA
 NM_009515 Wiskott-Aldrich syndrome homolog (human) (Was), mRNA [NM_009515] KLA .66 .67 .64 .65 .88 1.08 1.09
ATP 1.08 1.11 .87 1.23 .77 .51 .90
KLA/ATP .76 .70 .44 .83 .49 .61 .91
Wasf1
KLA  ATP  ATP+KLA
 NM_031877 WASP family 1 (Wasf1), mRNA [NM_031877] KLA .75 .69 .77 .81 .69 .66 .54
ATP 1.01 .97 .93 .98 .70 .66 .97
KLA/ATP .75 .73 .80 .79 .73 .67 .56
Wasf2
KLA  ATP  ATP+KLA
 AK150140 bone marrow macrophage cDNA, RIKEN full-length enriched library, clone:G530136J12 product:WAS protein family, member 2, full insert sequence [AK150140] KLA .58 .52 .52 .83 1.06 1.17 .91
ATP .97 .89 .93 .57 .72 .72 .86
KLA/ATP .55 .45 .56 .36 .45 .65 1.08
Wasf2
KLA  ATP  ATP+KLA
 NM_153423 WAS protein family, member 2 (Wasf2), mRNA [NM_153423] KLA .67 .75 .66 1.01 1.31 1.28 1.19
ATP 1.05 1.10 .82 .81 .82 .68 .92
KLA/ATP .75 .76 .73 .57 .61 .77 1.16
Wasl
KLA  ATP  ATP+KLA
 NM_028459 Wiskott-Aldrich syndrome-like (human) (Wasl), mRNA [NM_028459] KLA .88 .89 .96 .85 .97 1.08 1.14
ATP 1.08 .99 .71 .76 1.71 .91 .99
KLA/ATP .96 .84 .72 .84 1.51 .91 1.24