Microarray data for Cept1: fold-change ratios

Bone marrow-derived macrophage cells treated with Kdo2-Lipid A (KLA) and ATP

Gene Time course graph Description Treatment 15min 30min 1h 2h 4h 8h 20h
Cept1
KLA  ATP  ATP+KLA
 choline/ethanolaminephosphotransferase 1 (Cept1), mRNA [NM_133869] KLA 3.40 3.07 3.72 5.13 5.83 5.57 2.91
 ATP 1.09 1.05 1.09 .81 1.14 2.16 1.37
 ATP+KLA 3.35 3.19 4.07 2.89 3.10 3.27 4.09

Bone marrow-derived macrophage cells treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Cept1
25OHC/Ctl - treatment with 25-OHC / no treatment
25-OHC*/* - lipid depleted media containing compactin and treatment with 25-OHC / lipid depleted media containing compactin only
choline/ethanolaminephosphotransferase 1 (Cept1), mRNA [NM_133869] 25OHC/Ctl (?) 1.05 .99 1.05 .96 .97 .87 .94
 25-OHC*/* (?) 1.03 1.01 1.17 1.01 1.03 1.05 1.13
 
 

Thioglycolate-elicited macrophage cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Cept1
KLA  Compactin  Compactin+KLA
 choline/ethanolaminephosphotransferase 1 (Cept1), mRNA [NM_133869] KLA 1.09 .81 1.78 3.67 2.71 2.02 1.81
 Compactin .99 .90 1.10 1.05 1.02 1.06 1.17
 Compactin+KLA 1.06 1.07 2.01 2.57 2.14 2.27 2.21

RAW 264.7 cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Cept1
KLA  Compactin  Compactin+KLA
 choline/ethanolaminephosphotransferase 1 (Cept1), mRNA [NM_133869] KLA .83 .81 .84 1.18 1.88 1.31 1.57
 Compactin .82 .91 .85 .70 1.15 1.05 1.14
 Compactin+KLA .91 .90 .85 1.15 1.60 2.01 1.82