Microarray data for Chpt1: fold-change ratios

Bone marrow-derived macrophage cells treated with Kdo2-Lipid A (KLA) and ATP

Gene Time course graph Description Treatment 15min 30min 1h 2h 4h 8h 20h
Chpt1
KLA  ATP  ATP+KLA
 choline phosphotransferase 1 (Chpt1), mRNA [NM_144807] KLA 1.16 1.18 1.24 1.15 1.16 1.10 1.23
 ATP 1.01 1.05 1.16 1.09 .99 .97 .98
 ATP+KLA 1.20 1.15 1.13 1.18 1.17 1.33 1.25

Bone marrow-derived macrophage cells treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Chpt1
25OHC/Ctl - treatment with 25-OHC / no treatment
25-OHC*/* - lipid depleted media containing compactin and treatment with 25-OHC / lipid depleted media containing compactin only
choline phosphotransferase 1 (Chpt1), mRNA [NM_144807] 25OHC/Ctl (?) 1.05 1.05 1.05 1.05 1.04 1.03 1.04
 25-OHC*/* (?) 1.09 .98 .96 .92 1.02 1.00 .96
 
 

Thioglycolate-elicited macrophage cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Chpt1
KLA  Compactin  Compactin+KLA
 choline phosphotransferase 1 (Chpt1), mRNA [NM_144807] KLA 1.06 .89 1.01 1.08 1.25 1.27 1.60
 Compactin 1.00 .92 1.05 .99 1.00 1.00 1.13
 Compactin+KLA .96 .89 1.00 1.05 1.35 1.32 1.67

RAW 264.7 cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Chpt1
KLA  Compactin  Compactin+KLA
 choline phosphotransferase 1 (Chpt1), mRNA [NM_144807] KLA .96 1.02 1.00 .97 .91 .97 1.01
 Compactin 1.01 1.04 1.04 1.04 .90 .89 .89
 Compactin+KLA .95 .96 .95 1.05 .91 .88 .97