Microarray data for Degs1: fold-change ratios

Bone marrow-derived macrophage cells treated with Kdo2-Lipid A (KLA) and ATP

Gene Time course graph Description Treatment 15min 30min 1h 2h 4h 8h 20h
Degs1
KLA  ATP  ATP+KLA
degenerative spermatocyte homolog 1 (Drosophila) (Degs1), mRNA [NM_007853] KLA .83 .80 .78 .74 .58 .38 .67
 ATP 1.14 1.08 1.10 1.18 1.53 1.19 .96
 ATP+KLA .88 .88 .82 .78 .76 .57 .52

Bone marrow-derived macrophage cells treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Degs1
25OHC/Ctl - treatment with 25-OHC / no treatment
25-OHC*/* - lipid depleted media containing compactin and treatment with 25-OHC / lipid depleted media containing compactin only
degenerative spermatocyte homolog 1 (Drosophila) (Degs1), mRNA [NM_007853] 25OHC/Ctl (?) 1.01 1.05 1.03 1.17 1.22 1.33 1.17
 25-OHC*/* (?) 1.11 1.02 1.31 1.07 1.13 1.25 1.01
 
 

Thioglycolate-elicited macrophage cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Degs1
KLA  Compactin  Compactin+KLA
degenerative spermatocyte homolog 1 (Drosophila) (Degs1), mRNA [NM_007853] KLA .97 .91 .97 .77 .49 .42 .48
 Compactin .90 1.05 .96 .96 1.00 1.01 .90
 Compactin+KLA .87 1.04 1.07 .71 .43 .46 .61

RAW 264.7 cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Degs1
KLA  Compactin  Compactin+KLA
degenerative spermatocyte homolog 1 (Drosophila) (Degs1), mRNA [NM_007853] KLA .93 .95 1.02 1.31 1.38 1.07 .70
 Compactin .91 .77 .77 .84 1.09 1.23 1.21
 Compactin+KLA .96 .89 1.03 1.12 1.27 1.13 .93