Microarray data for Degs2: fold-change ratios

Bone marrow-derived macrophage cells treated with Kdo2-Lipid A (KLA) and ATP

Gene Time course graph Description Treatment 15min 30min 1h 2h 4h 8h 20h
Degs2
KLA  ATP  ATP+KLA
degenerative spermatocyte homolog 2 (Drosophila), lipid desaturase (Degs2), mRNA [NM_027299] KLA 1.03 .99 .93 .99 1.05 1.03 .94
 ATP 1.00 1.02 1.05 .97 1.06 .92 .99
 ATP+KLA 1.04 1.06 1.00 .93 1.00 .94 .94

Bone marrow-derived macrophage cells treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Degs2
25OHC/Ctl - treatment with 25-OHC / no treatment
25-OHC*/* - lipid depleted media containing compactin and treatment with 25-OHC / lipid depleted media containing compactin only
degenerative spermatocyte homolog 2 (Drosophila), lipid desaturase (Degs2), mRNA [NM_027299] 25OHC/Ctl (?) .94 1.07 1.05 1.03 .97 .92 1.06
 25-OHC*/* (?) .98 1.02 1.11 .97 .99 1.03 1.04
 
 

Thioglycolate-elicited macrophage cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Degs2
KLA  Compactin  Compactin+KLA
degenerative spermatocyte homolog 2 (Drosophila), lipid desaturase (Degs2), mRNA [NM_027299] KLA .96 1.00 .98 1.04 .98 .99 .99
 Compactin .97 1.04 .99 1.04 .97 1.06 1.01
 Compactin+KLA .98 1.04 1.02 1.03 1.02 1.04 .97

RAW 264.7 cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Degs2
KLA  Compactin  Compactin+KLA
degenerative spermatocyte homolog 2 (Drosophila), lipid desaturase (Degs2), mRNA [NM_027299] KLA 1.02 .99 1.00 1.07 .96 .93 .97
 Compactin .98 .92 1.00 1.00 .97 .98 .99
 Compactin+KLA .96 .99 1.04 .92 1.05 1.15 .98