Microarray data for Fdft1: fold-change ratios

Bone marrow-derived macrophage cells treated with Kdo2-Lipid A (KLA) and ATP

Gene Time course graph Description Treatment 15min 30min 1h 2h 4h 8h 20h
Fdft1
KLA  ATP  ATP+KLA
 farnesyl diphosphate farnesyl transferase 1 (Fdft1), mRNA [NM_010191] KLA .96 .99 .98 .99 .88 .78 .77
 ATP 1.00 1.01 1.08 1.10 .93 1.02 1.28
 ATP+KLA .98 .97 .98 1.04 .97 .87 .73

Bone marrow-derived macrophage cells treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Fdft1
25OHC/Ctl - treatment with 25-OHC / no treatment
25-OHC*/* - lipid depleted media containing compactin and treatment with 25-OHC / lipid depleted media containing compactin only
farnesyl diphosphate farnesyl transferase 1 (Fdft1), mRNA [NM_010191] 25OHC/Ctl (?) 1.03 .93 .79 .70 .69 .74 .62
 25-OHC*/* (?) 1.02 .95 .75 .57 .52 .58 .57
 
 

Thioglycolate-elicited macrophage cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Fdft1
KLA  Compactin  Compactin+KLA
 farnesyl diphosphate farnesyl transferase 1 (Fdft1), mRNA [NM_010191] KLA 1.02 1.10 .95 1.04 .84 .70 .67
 Compactin 1.00 1.06 1.05 1.04 1.11 1.16 1.08
 Compactin+KLA 1.04 1.03 1.01 1.10 1.01 .76 .75

RAW 264.7 cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Fdft1
KLA  Compactin  Compactin+KLA
 farnesyl diphosphate farnesyl transferase 1 (Fdft1), mRNA [NM_010191] KLA 1.14 1.07 1.10 1.01 1.07 1.05 1.05
 Compactin 1.11 1.12 1.08 1.24 1.16 1.10 1.10
 Compactin+KLA 1.11 1.06 1.19 1.17 1.23 1.13 1.24