Microarray data for Fdps: fold-change ratios

Bone marrow-derived macrophage cells treated with Kdo2-Lipid A (KLA) and ATP

Gene Time course graph Description Treatment 15min 30min 1h 2h 4h 8h 20h
Fdps
KLA  ATP  ATP+KLA
 13 days embryo male testis cDNA, RIKEN full-length enriched library, clone:6030492I17 product:farnesyl diphosphate synthetase, full insert sequence. [AK077979] KLA .76 .79 .79 .69 .65 .37 .49
 ATP .63 .70 .85 .30 .46 .89 .86
 ATP+KLA .54 .52 .63 .39 .42 .40 .31
Fdps
KLA  ATP  ATP+KLA
 farnesyl diphosphate synthetase (Fdps), mRNA [NM_134469] KLA .87 .93 .89 .97 .76 .43 .48
 ATP 1.12 1.10 1.05 1.23 1.05 .60 .88
 ATP+KLA .93 .99 1.00 1.02 .70 .45 .33

Bone marrow-derived macrophage cells treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Fdps
25OHC/Ctl - treatment with 25-OHC / no treatment
25-OHC*/* - lipid depleted media containing compactin and treatment with 25-OHC / lipid depleted media containing compactin only
13 days embryo male testis cDNA, RIKEN full-length enriched library, clone:6030492I17 product:farnesyl diphosphate synthetase, full insert sequence. [AK077979] 25OHC/Ctl (?) .79 .35 .28 .41 .39 .36 .24
 25-OHC*/* (?) .68 .15 .12 .13 .14 .12 .15
 
 
Fdps
25OHC/Ctl - treatment with 25-OHC / no treatment
25-OHC*/* - lipid depleted media containing compactin and treatment with 25-OHC / lipid depleted media containing compactin only
farnesyl diphosphate synthetase (Fdps), mRNA [NM_134469] 25OHC/Ctl (?) .91 .99 .78 .53 .28 .31 .24
 25-OHC*/* (?) 1.02 1.03 .78 .39 .19 .14 .16
 
 

Thioglycolate-elicited macrophage cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Fdps
KLA  Compactin  Compactin+KLA
 13 days embryo male testis cDNA, RIKEN full-length enriched library, clone:6030492I17 product:farnesyl diphosphate synthetase, full insert sequence. [AK077979] KLA .71 .76 .78 .83 .61 .79 .78
 Compactin 1.09 1.29 1.22 1.16 1.12 1.06 .97
 Compactin+KLA .80 .85 .78 .95 .62 .75 .86
Fdps
KLA  Compactin  Compactin+KLA
 farnesyl diphosphate synthetase (Fdps), mRNA [NM_134469] KLA 1.07 .94 1.01 1.10 .87 .69 .83
 Compactin 1.01 1.04 1.09 1.23 1.20 1.37 1.02
 Compactin+KLA .91 1.19 1.32 .99 1.01 1.01 1.22

RAW 264.7 cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Fdps
KLA  Compactin  Compactin+KLA
 13 days embryo male testis cDNA, RIKEN full-length enriched library, clone:6030492I17 product:farnesyl diphosphate synthetase, full insert sequence. [AK077979] KLA 1.03 .76 .50 .41 .63 .72 .55
 Compactin .90 1.03 1.18 .88 1.08 .99 1.14
 Compactin+KLA .98 .84 .61 .59 .73 .58 .65
Fdps
KLA  Compactin  Compactin+KLA
 farnesyl diphosphate synthetase (Fdps), mRNA [NM_134469] KLA .98 .85 .85 .75 .72 .70 .80
 Compactin .89 .86 .92 .86 1.19 1.22 1.05
 Compactin+KLA .89 .87 .88 .85 .99 .90 1.14