Microarray data for Ggps1: fold-change ratios

Bone marrow-derived macrophage cells treated with Kdo2-Lipid A (KLA) and ATP

Gene Time course graph Description Treatment 15min 30min 1h 2h 4h 8h 20h
Ggps1
KLA  ATP  ATP+KLA
 adult male spinal cord cDNA, RIKEN full-length enriched library, clone:A330064P13 product:geranylgeranyl diphosphate synthase 1, full insert sequence [AK138564] KLA 1.17 1.19 1.22 1.09 1.12 1.25 1.22
 ATP 1.02 1.06 .90 .91 1.06 1.11 .92
 ATP+KLA 1.23 1.10 1.10 1.19 1.22 1.09 .89
Ggps1
KLA  ATP  ATP+KLA
 geranylgeranyl diphosphate synthase 1 (Ggps1), mRNA [NM_010282] KLA 1.17 1.17 1.29 1.28 1.22 1.57 1.73
 ATP .88 .84 .99 .85 .97 2.03 2.04
 ATP+KLA 1.08 1.10 1.34 1.11 1.23 1.95 2.71

Bone marrow-derived macrophage cells treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Ggps1
25OHC/Ctl - treatment with 25-OHC / no treatment
25-OHC*/* - lipid depleted media containing compactin and treatment with 25-OHC / lipid depleted media containing compactin only
adult male spinal cord cDNA, RIKEN full-length enriched library, clone:A330064P13 product:geranylgeranyl diphosphate synthase 1, full insert sequence [AK138564] 25OHC/Ctl (?) .95 .94 1.02 .89 .99 1.03 1.17
 25-OHC*/* (?) .97 1.01 .91 .99 .96 1.02 1.19
 
 
Ggps1
25OHC/Ctl - treatment with 25-OHC / no treatment
25-OHC*/* - lipid depleted media containing compactin and treatment with 25-OHC / lipid depleted media containing compactin only
geranylgeranyl diphosphate synthase 1 (Ggps1), mRNA [NM_010282] 25OHC/Ctl (?) 1.06 1.08 .98 1.13 1.03 1.11 1.26
 25-OHC*/* (?) 1.03 1.10 1.08 1.07 1.03 1.15 1.50
 
 

Thioglycolate-elicited macrophage cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Ggps1
KLA  Compactin  Compactin+KLA
 adult male spinal cord cDNA, RIKEN full-length enriched library, clone:A330064P13 product:geranylgeranyl diphosphate synthase 1, full insert sequence [AK138564] KLA 1.09 .86 .88 .99 1.14 1.11 1.16
 Compactin 1.00 .95 1.00 .99 .99 1.05 1.13
 Compactin+KLA .98 .82 .83 1.01 1.23 1.03 1.09
Ggps1
KLA  Compactin  Compactin+KLA
 geranylgeranyl diphosphate synthase 1 (Ggps1), mRNA [NM_010282] KLA 1.06 .94 1.11 1.34 1.55 1.59 1.85
 Compactin 1.00 .96 1.10 1.03 1.01 1.04 1.11
 Compactin+KLA 1.05 .90 1.15 1.33 1.65 1.56 1.72

RAW 264.7 cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Ggps1
KLA  Compactin  Compactin+KLA
 adult male spinal cord cDNA, RIKEN full-length enriched library, clone:A330064P13 product:geranylgeranyl diphosphate synthase 1, full insert sequence [AK138564] KLA .92 .95 1.03 1.11 1.11 1.05 .97
 Compactin .97 1.07 1.02 1.04 1.03 1.00 1.18
 Compactin+KLA 1.00 1.05 .99 1.04 1.12 1.10 .95
Ggps1
KLA  Compactin  Compactin+KLA
 geranylgeranyl diphosphate synthase 1 (Ggps1), mRNA [NM_010282] KLA .96 1.15 1.24 1.43 1.68 1.95 2.35
 Compactin .95 1.07 1.05 1.05 .93 .99 1.11
 Compactin+KLA .97 1.17 1.12 1.41 1.61 1.80 2.23