Microarray data for Idi1: fold-change ratios

Bone marrow-derived macrophage cells treated with Kdo2-Lipid A (KLA) and ATP

Gene Time course graph Description Treatment 15min 30min 1h 2h 4h 8h 20h
Idi1
KLA  ATP  ATP+KLA
 isopentenyl-diphosphate delta isomerase (Idi1), transcript variant 2, mRNA [NM_177960] KLA 1.43 1.49 1.51 1.22 .89 .45 .52
 ATP 1.02 1.06 1.43 1.32 .86 .62 1.15
 ATP+KLA 1.37 1.36 1.52 1.45 .84 .35 .32

Bone marrow-derived macrophage cells treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Idi1
25OHC/Ctl - treatment with 25-OHC / no treatment
25-OHC*/* - lipid depleted media containing compactin and treatment with 25-OHC / lipid depleted media containing compactin only
isopentenyl-diphosphate delta isomerase (Idi1), transcript variant 2, mRNA [NM_177960] 25OHC/Ctl (?) 1.05 .88 .67 .33 .30 .28 .28
 25-OHC*/* (?) 1.00 .94 .56 .15 .07 .08 .10
 
 

Thioglycolate-elicited macrophage cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Idi1
KLA  Compactin  Compactin+KLA
 isopentenyl-diphosphate delta isomerase (Idi1), transcript variant 2, mRNA [NM_177960] KLA 1.08 1.20 1.29 1.15 .83 .56 .64
 Compactin .98 .90 1.04 1.04 1.15 1.08 1.08
 Compactin+KLA 1.00 1.30 1.44 1.32 1.06 .65 .69

RAW 264.7 cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Idi1
KLA  Compactin  Compactin+KLA
 isopentenyl-diphosphate delta isomerase (Idi1), transcript variant 2, mRNA [NM_177960] KLA 1.04 1.27 1.29 1.10 .88 .85 .55
 Compactin .99 .93 .96 1.07 .97 1.04 .87
 Compactin+KLA 1.05 1.13 1.42 1.18 .93 .69 .60