Microarray data for Lass4: fold-change ratios

Bone marrow-derived macrophage cells treated with Kdo2-Lipid A (KLA) and ATP

Gene Time course graph Description Treatment 15min 30min 1h 2h 4h 8h 20h
Lass4
KLA  ATP  ATP+KLA
 16 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:9630036I10 product:longevity assurance homolog 4 (S. cerevisiae), full insert sequence. [AK036108] KLA .86 .82 .81 .76 .78 .71 .76
 ATP 1.05 .97 .93 .71 .86 .79 .75
 ATP+KLA .90 .81 .80 .72 .80 .74 .72
Lass4
KLA  ATP  ATP+KLA
 LAG1 homolog, ceramide synthase 4 (Lass4), mRNA [NM_026058] KLA .64 .61 .59 .67 .59 .56 .55
 ATP .91 .92 1.09 .90 .62 .55 .61
 ATP+KLA .63 .65 .73 .66 .60 .55 .55

Bone marrow-derived macrophage cells treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Lass4
25OHC/Ctl - treatment with 25-OHC / no treatment
25-OHC*/* - lipid depleted media containing compactin and treatment with 25-OHC / lipid depleted media containing compactin only
16 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:9630036I10 product:longevity assurance homolog 4 (S. cerevisiae), full insert sequence. [AK036108] 25OHC/Ctl (?) .99 1.09 1.00 1.01 1.03 .90 .95
 25-OHC*/* (?) .86 1.09 .96 1.03 1.01 .92 .99
 
 
Lass4
25OHC/Ctl - treatment with 25-OHC / no treatment
25-OHC*/* - lipid depleted media containing compactin and treatment with 25-OHC / lipid depleted media containing compactin only
LAG1 homolog, ceramide synthase 4 (Lass4), mRNA [NM_026058] 25OHC/Ctl (?) 1.01 1.00 1.06 1.05 1.05 1.10 1.18
 25-OHC*/* (?) .97 1.09 .87 1.01 .88 .85 .85
 
 

Thioglycolate-elicited macrophage cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Lass4
KLA  Compactin  Compactin+KLA
 16 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:9630036I10 product:longevity assurance homolog 4 (S. cerevisiae), full insert sequence. [AK036108] KLA 1.01 1.02 1.01 1.03 .93 .88 .92
 Compactin 1.01 .96 1.10 1.08 1.03 1.04 .97
 Compactin+KLA 1.03 .98 1.02 1.05 .84 .98 .97
Lass4
KLA  Compactin  Compactin+KLA
 LAG1 homolog, ceramide synthase 4 (Lass4), mRNA [NM_026058] KLA 1.04 .93 1.02 .85 .63 .54 .45
 Compactin 1.07 .95 .94 1.04 .97 1.04 1.05
 Compactin+KLA 1.01 .93 1.02 .87 .65 .53 .46

RAW 264.7 cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Lass4
KLA  Compactin  Compactin+KLA
 16 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:9630036I10 product:longevity assurance homolog 4 (S. cerevisiae), full insert sequence. [AK036108] KLA .91 .93 1.12 1.07 1.16 1.21 1.11
 Compactin 1.02 1.05 1.00 .99 1.00 1.00 1.07
 Compactin+KLA .94 .97 1.07 .97 1.11 1.24 1.17
Lass4
KLA  Compactin  Compactin+KLA
 LAG1 homolog, ceramide synthase 4 (Lass4), mRNA [NM_026058] KLA .94 .99 1.23 1.60 2.24 2.32 2.72
 Compactin .94 .99 1.02 .97 .88 .96 1.21
 Compactin+KLA 1.01 .97 1.26 1.46 1.88 2.37 2.65