Microarray data for Nsdhl: fold-change ratios

Bone marrow-derived macrophage cells treated with Kdo2-Lipid A (KLA) and ATP

Gene Time course graph Description Treatment 15min 30min 1h 2h 4h 8h 20h
Nsdhl
KLA  ATP  ATP+KLA
 activated spleen cDNA, RIKEN full-length enriched library, clone:F830111P16 product:unclassifiable, full insert sequence [AK156993] KLA 1.06 .94 .95 .88 1.09 .86 .76
 ATP 1.14 1.03 1.03 .75 .75 .92 1.02
 ATP+KLA 1.05 .98 .92 .70 .84 .71 .76
Nsdhl
KLA  ATP  ATP+KLA
 NAD(P) dependent steroid dehydrogenase-like (Nsdhl), mRNA [NM_010941] KLA .98 1.05 1.03 .95 .97 .87 .89
 ATP 1.02 1.16 1.11 1.33 .91 .57 1.05
 ATP+KLA 1.08 1.02 .86 1.20 .77 .58 .47

Bone marrow-derived macrophage cells treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Nsdhl
25OHC/Ctl - treatment with 25-OHC / no treatment
25-OHC*/* - lipid depleted media containing compactin and treatment with 25-OHC / lipid depleted media containing compactin only
NAD(P) dependent steroid dehydrogenase-like (Nsdhl), mRNA [NM_010941] 25OHC/Ctl (?) .98 .95 .92 .61 .55 .57 .46
 25-OHC*/* (?) 1.06 .90 1.04 .39 .26 .25 .22
 
 
Nsdhl
25OHC/Ctl - treatment with 25-OHC / no treatment
25-OHC*/* - lipid depleted media containing compactin and treatment with 25-OHC / lipid depleted media containing compactin only
activated spleen cDNA, RIKEN full-length enriched library, clone:F830111P16 product:unclassifiable, full insert sequence [AK156993] 25OHC/Ctl (?) .96 .89 .61 .74 .74 .67 .57
 25-OHC*/* (?) .77 .54 .39 .39 .33 .29 .31
 
 

Thioglycolate-elicited macrophage cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Nsdhl
KLA  Compactin  Compactin+KLA
 activated spleen cDNA, RIKEN full-length enriched library, clone:F830111P16 product:unclassifiable, full insert sequence [AK156993] KLA 1.01 .89 .83 .82 .83 .88 .84
 Compactin .98 1.03 .96 .86 1.03 .97 .87
 Compactin+KLA .96 .92 .83 .80 .80 .90 .91
Nsdhl
KLA  Compactin  Compactin+KLA
 NAD(P) dependent steroid dehydrogenase-like (Nsdhl), mRNA [NM_010941] KLA 1.00 .96 1.06 .94 .83 .85 .99
 Compactin 1.03 .94 1.16 1.10 .99 1.07 1.12
 Compactin+KLA 1.06 .98 1.03 .93 1.09 .91 1.06

RAW 264.7 cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Nsdhl
KLA  Compactin  Compactin+KLA
 NAD(P) dependent steroid dehydrogenase-like (Nsdhl), mRNA [NM_010941] KLA 1.18 1.05 1.16 .95 .89 .95 .90
 Compactin 1.13 1.09 1.08 1.23 1.16 1.06 .78
 Compactin+KLA 1.12 .99 1.12 1.03 1.19 .95 .97
Nsdhl
KLA  Compactin  Compactin+KLA
 activated spleen cDNA, RIKEN full-length enriched library, clone:F830111P16 product:unclassifiable, full insert sequence [AK156993] KLA 1.04 .95 .87 .80 .89 .96 .91
 Compactin 1.03 1.01 1.04 .98 1.08 .95 1.04
 Compactin+KLA 1.08 .93 .93 .84 .86 .88 .95