Microarray data for Pemt: fold-change ratios

Bone marrow-derived macrophage cells treated with Kdo2-Lipid A (KLA) and ATP

Gene Time course graph Description Treatment 15min 30min 1h 2h 4h 8h 20h
Pemt
KLA  ATP  ATP+KLA
 phosphatidylethanolamine N-methyltransferase (Pemt), nuclear gene encoding mitochondrial protein, mRNA [NM_008819] KLA 1.00 1.08 1.08 .99 .92 .83 .93
 ATP 1.08 1.16 1.04 1.22 1.02 .89 .84
 ATP+KLA 1.14 1.10 .92 1.05 .83 .76 .71

Bone marrow-derived macrophage cells treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Pemt
25OHC/Ctl - treatment with 25-OHC / no treatment
25-OHC*/* - lipid depleted media containing compactin and treatment with 25-OHC / lipid depleted media containing compactin only
phosphatidylethanolamine N-methyltransferase (Pemt), nuclear gene encoding mitochondrial protein, mRNA [NM_008819] 25OHC/Ctl (?) .99 .92 1.06 .91 .88 1.05 1.20
 25-OHC*/* (?) 1.11 .92 1.38 .87 1.00 .97 1.05
 
 

Thioglycolate-elicited macrophage cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Pemt
KLA  Compactin  Compactin+KLA
 phosphatidylethanolamine N-methyltransferase (Pemt), nuclear gene encoding mitochondrial protein, mRNA [NM_008819] KLA 1.02 1.03 1.06 1.00 1.06 1.08 1.14
 Compactin 1.08 1.04 1.00 1.05 1.01 1.10 1.17
 Compactin+KLA .99 1.02 1.05 1.06 .98 1.05 1.20

RAW 264.7 cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Pemt
KLA  Compactin  Compactin+KLA
 phosphatidylethanolamine N-methyltransferase (Pemt), nuclear gene encoding mitochondrial protein, mRNA [NM_008819] KLA .97 1.08 1.02 1.06 1.00 .91 .95
 Compactin 1.04 1.05 1.04 1.01 .96 1.10 1.01
 Compactin+KLA .89 1.00 1.03 1.14 .91 .90 .99