Microarray data for Pgs1: fold-change ratios

Bone marrow-derived macrophage cells treated with Kdo2-Lipid A (KLA) and ATP

Gene Time course graph Description Treatment 15min 30min 1h 2h 4h 8h 20h
Pgs1
KLA  ATP  ATP+KLA
 phosphatidylglycerophosphate synthase 1 (Pgs1), mRNA [NM_133757] KLA 2.65 2.70 2.52 2.72 2.54 2.28 1.89
 ATP .97 .98 1.06 1.17 1.57 2.20 1.91
 ATP+KLA 2.60 2.62 2.92 2.95 2.95 2.64 2.37

Bone marrow-derived macrophage cells treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Pgs1
25OHC/Ctl - treatment with 25-OHC / no treatment
25-OHC*/* - lipid depleted media containing compactin and treatment with 25-OHC / lipid depleted media containing compactin only
phosphatidylglycerophosphate synthase 1 (Pgs1), mRNA [NM_133757] 25OHC/Ctl (?) 1.00 1.04 1.02 1.02 1.03 1.05 1.20
 25-OHC*/* (?) 1.01 1.05 1.05 1.03 1.04 1.10 1.22
 
 

Thioglycolate-elicited macrophage cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Pgs1
KLA  Compactin  Compactin+KLA
 phosphatidylglycerophosphate synthase 1 (Pgs1), mRNA [NM_133757] KLA .91 1.20 1.75 2.66 2.22 2.07 1.89
 Compactin 1.02 1.00 .93 .98 .94 .98 .96
 Compactin+KLA .97 1.11 1.50 2.58 2.28 1.97 1.67

RAW 264.7 cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Pgs1
KLA  Compactin  Compactin+KLA
 phosphatidylglycerophosphate synthase 1 (Pgs1), mRNA [NM_133757] KLA 1.08 1.03 1.28 1.43 1.40 1.47 1.30
 Compactin 1.14 1.04 1.06 1.11 1.12 1.20 1.03
 Compactin+KLA 1.18 1.00 1.21 1.65 1.47 1.51 1.27