Microarray data for Ptdss1: fold-change ratios

Bone marrow-derived macrophage cells treated with Kdo2-Lipid A (KLA) and ATP

Gene Time course graph Description Treatment 15min 30min 1h 2h 4h 8h 20h
Ptdss1
KLA  ATP  ATP+KLA
 phosphatidylserine synthase 1 (Ptdss1), mRNA [NM_008959] KLA .88 .95 .96 .86 .88 .92 1.05
 ATP 1.02 1.05 .90 1.08 .99 .93 1.17
 ATP+KLA .95 .93 .81 .85 .67 .83 1.10

Bone marrow-derived macrophage cells treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Ptdss1
25OHC/Ctl - treatment with 25-OHC / no treatment
25-OHC*/* - lipid depleted media containing compactin and treatment with 25-OHC / lipid depleted media containing compactin only
phosphatidylserine synthase 1 (Ptdss1), mRNA [NM_008959] 25OHC/Ctl (?) .95 .89 .99 .91 .90 .96 .97
 25-OHC*/* (?) 1.01 .90 1.19 .90 .96 .98 .85
 
 

Thioglycolate-elicited macrophage cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Ptdss1
KLA  Compactin  Compactin+KLA
 phosphatidylserine synthase 1 (Ptdss1), mRNA [NM_008959] KLA .97 .89 1.05 .97 .88 .97 .95
 Compactin 1.02 .99 1.07 1.04 .90 1.06 1.00
 Compactin+KLA 1.00 .85 .95 .99 .95 .98 .93

RAW 264.7 cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Ptdss1
KLA  Compactin  Compactin+KLA
 phosphatidylserine synthase 1 (Ptdss1), mRNA [NM_008959] KLA 1.02 1.00 1.12 1.12 1.07 1.07 1.12
 Compactin 1.15 1.14 1.04 1.21 1.10 1.01 1.05
 Compactin+KLA 1.16 1.02 1.06 1.05 1.03 1.10 1.16