Microarray data for Ptgds: fold-change ratios

Bone marrow-derived macrophage cells treated with Kdo2-Lipid A (KLA) and ATP

Gene Time course graph Description Treatment 15min 30min 1h 2h 4h 8h 20h
Ptgds
KLA  ATP  ATP+KLA
prostaglandin D2 synthase (brain) (Ptgds), mRNA [NM_008963] KLA 1.19 1.16 1.11 1.19 1.04 .98 .93
 ATP .99 .99 1.10 1.07 1.02 1.00 .97
 ATP+KLA 1.18 1.18 1.31 1.39 1.09 .89 .90

Bone marrow-derived macrophage cells treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Ptgds
25OHC/Ctl - treatment with 25-OHC / no treatment
25-OHC*/* - lipid depleted media containing compactin and treatment with 25-OHC / lipid depleted media containing compactin only
prostaglandin D2 synthase (brain) (Ptgds), mRNA [NM_008963] 25OHC/Ctl (?) 1.00 .95 1.03 1.00 1.04 1.00 .96
 25-OHC*/* (?) .93 .94 .93 .95 1.01 1.01 1.01
 
 

Thioglycolate-elicited macrophage cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Ptgds
KLA  Compactin  Compactin+KLA
prostaglandin D2 synthase (brain) (Ptgds), mRNA [NM_008963] KLA .97 .99 1.03 1.06 1.04 1.02 1.05
 Compactin 1.07 1.02 1.04 1.03 1.05 1.02 1.03
 Compactin+KLA 1.05 1.03 1.13 1.12 1.10 .99 1.07

RAW 264.7 cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Ptgds
KLA  Compactin  Compactin+KLA
prostaglandin D2 synthase (brain) (Ptgds), mRNA [NM_008963] KLA 1.11 1.02 1.13 1.28 1.05 1.07 .98
 Compactin 1.04 1.00 1.16 1.08 1.10 1.07 1.09
 Compactin+KLA 1.01 1.06 1.17 1.16 1.12 1.11 .88