Lipidomics studies on macrophages

Sphingolipids

Legend:	: View data/graphs for replicates : View graphs of average of replicates Kdo+Comp = (Kdo₂-Lipid A + Compactin)/Control Kdo = Kdo₂-Lipid A/Control; Comp = Compactin/Control RepressionInduction Measurements were in pmol/ug DNA

LM_ID	Name	Kdo+Comp Kdo Comp 0.5 hrs	Kdo+Comp Kdo Comp 1 hr	Kdo+Comp Kdo Comp 2 hrs	Kdo+Comp Kdo Comp 4 hrs	Kdo+Comp Kdo Comp 8 hrs	Kdo+Comp Kdo Comp 12 hrs	Kdo+Comp Kdo Comp 24 hrs
LMSP02010001	C14 Cer	1.12 1.62 1.12	1.11 1.64 1.79	1.1 1.03 0.903	1.67 2.05 1.67	5 4.36 2.45	2.04 2.68 1.12	2.94 1.69 0.914
LMSP02010004	C16 Cer	0.776 0.823 0.99	0.959 0.968 1.03	0.915 1.01 1.03	0.971 1.17 1.09	1.18 1.29 0.996	1.4 1.85 0.967	1.86 1.89 0.95
LMSP02010006	C18 Cer	1.04 0.91 0.869	1.3 1.31 1.14	1.31 1.22 1.12	1.02 1.33 1.2	1.3 1.1 1.02	1.15 1.5 0.963	1.16 1.14 0.943
LMSP02010003	C18:1 Cer	0.973 0.811 0.811	1.28 1.03 2	0.949 0.385 1.05	1.2 2 1.6	1.73 1.64 1.45	1 2.24 0.92	2 1.31 1.31
LMSP02010007	C20 Cer	0.96 0.896 0.864	1.23 1.24 1.32	1.15 1.16 1.1	0.99 1.03 0.798	1.31 1.17 1.89	1.42 1.73 1.28	1.36 1.31 1.31
LMSP02010008	C22 Cer	0.802 0.786 0.931	0.973 1.05 0.982	0.889 0.932 1.03	0.811 1.07 1.15	1.14 0.933 1.23	0.987 1.17 1.22	1.02 1.02 1.11
LMSP02010012	C24 Cer	0.848 0.896 0.93	0.829 0.936 0.94	0.743 0.847 0.96	0.636 1 1.01	0.975 0.906 1.17	1 0.903 1.03	1.54 1.28 1.23
LMSP02010009	C24:1 Cer	0.657 0.757 0.83	0.579 0.62 0.915	0.516 0.71 0.853	0.628 0.895 0.976	0.857 0.887 1.05	0.983 1.09 1.06	1.63 1.57 1.19
LMSP02010011	C26 Cer	1.37 0.767 0.967	0.667 0.815 0.704	0.5 0.867 1.03	0.9 0.733 0.633	0.742 0.871 0.548	1.9 2.62 1.1	1.17 1.17 0.917
LMSP02010010	C26:1 Cer	1.02 1.15 1.07	0.836 0.656 0.77	1.03 1.83 1.22	2.29 2.54 1.64	1.8 1.52 1.46	1.94 1.59 1.29	3.65 3.26 1.42
LMSP03010028	C14 Sphingomyelin	0.973 1.18 0.968	1.06 1.07 1.11	1.03 1.04 0.959	1.14 1.24 1.03	1.29 1.41 1.13	1.23 1.44 0.851	1.47 1.65 1.01
LMSP03010003	C16 Sphingomyelin	0.928 1.16 0.928	1.07 1.08 1.04	1.01 0.997 0.948	0.996 1.2 1.05	1.12 1.2 1.07	1.04 1.15 0.888	1.27 1.29 0.988
LMSP03010001	C18 Sphingomyelin	0.867 1.22 0.925	1.08 1.11 1.06	0.925 0.921 0.886	0.989 1.16 0.96	1.23 1.21 1.13	1.13 1.09 0.914	1.18 1.04 1.06
LMSP03010029	C18:1 Sphingomyelin	1.08 1.24 1.09	1.14 1.23 1.02	0.986 1.05 1.07	1.03 1.04 1.03	1.29 1.26 1.13	1.15 1.4 1	1.34 1.2 0.967
LMSP03010005	C20 Sphingomyelin	0.875 1.24 0.922	1.07 1.16 1.07	1.07 1.03 0.957	1.1 1.28 1.09	1.19 1.21 1.09	1.16 1.05 0.939	1.24 1.09 1.16
LMSP03010006	C22 Sphingomyelin	0.889 1.18 0.897	1.13 1.11 1.1	1.07 1.02 0.982	0.99 1.25 1	1.19 1.28 1.05	1.16 1.04 0.895	1.32 1.12 1.15
LMSP03010008	C24 Sphingomyelin	0.911 1.24 0.9	1.14 1.08 1.09	1.1 1.04 0.989	0.969 1.2 1	1.16 1.31 1.04	1.07 1.07 0.889	1.35 1.15 1.14
LMSP03010007	C24:1 Sphingomyelin	0.895 1.2 0.879	1.2 1.17 1.16	1.02 1.02 0.992	0.982 1.17 1.03	1.12 1.23 1.05	1.07 1.08 0.958	1.27 1.11 1.05
LMSP03010010	C26 Sphingomyelin	0.828 0.914 0.954	1.14 1.19 1.05	0.78 0.711 0.799	1.16 1.18 1.19	1.44 1.23 1.25	1.18 1.12 1.18	1 0.768 0.829
LMSP03010009	C26:1 Sphingomyelin	0.851 1.05 0.846	1.13 1.09 1.04	0.978 0.919 0.92	1.13 1.23 1.07	1.15 1.29 1.12	1.23 1.33 0.958	1.37 1.28 0.992
LMSP0501AA26	C14 GlcCer	0.7 0.967 1.03	1 1.15 0.852	0.704 1.07 1.04	1.33 1.42 1.17	2.31 2.35 1.12	2.52 3.2 1.16	1.64 2.14 0.929
LMSP0501AA03	C16 GlcCer	1.04 1.03 1.06	1.01 1.07 1	1.02 0.942 0.917	1.06 1.25 1	1.68 1.61 1.11	1.89 1.95 1.04	2.25 2.35 1.2
LMSP0501AA05	C18 GlcCer	1.21 1.08 1.42	0.955 1.08 1.04	1 0.961 0.901	1.19 1.25 0.986	1.57 1.37 1.05	1.78 1.52 1.43	1.53 1.47 1.27
LMSP0501AA27	C18:1 GlcCer	0.9 1 0.9	1.67 0.833 0.833	- - -	- - -	- - -	- - -	0.833 1.25 0.833
LMSP0501AA06	C20 GlcCer	1.38 1.35 1.5	0.997 1.04 0.91	1.3 1.05 0.893	1.04 1.33 0.963	1.36 1.51 1.2	1.87 1.27 1	1.55 1.03 1.24
LMSP0501AA07	C22 GlcCer	1.11 1.01 1.09	0.914 0.937 1.01	1.16 0.957 0.953	1.05 1.22 0.987	1.53 1.45 1.09	1.5 1.42 0.986	1.57 1.24 1.26
LMSP0501AA09	C24 GlcCer	1.09 0.967 1.07	0.954 0.997 1.02	1.11 0.802 0.899	0.937 1.12 0.91	1.42 1.45 1.1	1.18 1.24 0.889	1.54 1.4 1.16
LMSP0501AA08	C24:1 GlcCer	1 1.04 1.14	0.956 1.03 1.02	1.08 0.96 0.96	0.968 1.14 1.05	1.39 1.29 1.01	1.31 1.31 0.948	1.86 1.75 1.27
LMSP0501AA11	C26 GlcCer	1.2 0.96 0.72	0.955 1.95 1.23	0.792 0.5 0.917	0.85 1.2 0.7	3.67 3.22 1.89	1.04 1.42 0.667	1.25 2.95 1.1
LMSP0501AA10	C26:1 GlcCer	1.28 0.868 0.849	0.873 1.02 1.02	1.43 1.36 0.857	0.875 1.07 0.982	1.59 1.64 0.636	1.97 1.91 1.47	2.73 2.68 1.32
LMSP05010030	C14DH Cer	2.73 0.629 0.608	0.389 0.651 0.846	0.658 0.983 1.09	0.696 1.46 1.33	1.01 1.04 0.5	0.342 0.342 0.675	2.4 1.29 1
LMSP02020001	C16DH Cer	1.24 1.32 0.734	2.26 1.51 0.915	0.631 1.09 0.37	1.32 1.43 0.904	1.39 1.46 1.42	1.09 1.92 1.24	1.77 1.58 1.07
LMSP02020015	C18:1DH Cer	0.538 2 0.513	2.85 1.02 1.69	- - -	0.381 0.683 0.63	3.84 1.34 2.03	1.44 2.42 0.313	0.977 1.67 1.45
LMSP02020008	C18DH Cer	1.45 0.882 1.2	2.41 1.31 0.989	2.65 1.72 0.603	1.79 1.45 1.03	1.6 1.21 0.727	1.49 1.49 0.989	1.39 1.63 0.576
LMSP02020009	C20DH Cer	0.771 1.9 1.35	3.58 6.31 3.64	2.33 1.31 1.45	1.87 4.02 1.98	0.517 0.231 0.857	1.78 0.446 1.83	1.24 1.93 1.03
LMSP02020010	C22DH Cer	2.33 1.65 2.02	4.33 2.71 0.518	3.47 7.42 3.68	1.92 0.857 1.46	1.58 2.38 0.99	1.12 4.47 1.18	0.847 0.445 1.07
LMSP02020011	C24:1DH Cer	1.48 1.1 0.804	1.03 1.19 1.14	0.712 0.707 1.38	0.608 0.617 1.46	0.742 0.657 1.03	1.26 0.901 1.26	2.17 0.909 1.48
LMSP02020012	C24DH Cer	- - -	1.52 2.42 3.33	- - -	0.908 0.634 0.941	1.52 0.753 0.485	0.43 0.361 0.6	1.3 0.523 2.58
LMSP02020013	C26:1DH Cer	- - -	1.11 0.481 0.296	- - -	0.171 0.2 0.943	3.79 0.429 1.21	0.047 0.189 0.386	1.11 1.3 1.33
LMSP02020014	C26DH Cer	- - -	- - -	- - -	3.35 1.38 0.462	2.71 0.921 0.395	- - -	2.19 1.86 1.52
LMSP03010030	C14DH Sphingomyelin	1.02 1.05 0.951	1.04 1.14 1.28	0.924 1.18 1.02	1.07 1.37 1.04	1.61 1.43 0.932	1.45 1.27 0.958	1.72 2.04 1.03
LMSP03010004	C16DH Sphingomyelin	1.04 0.932 0.893	1 1.15 1.02	1.08 0.989 0.82	1.17 1.21 1.12	1.24 1.11 1.06	0.816 0.982 0.782	1.38 1.31 0.974
LMSP03010031	C18:1DH Sphingomyelin	0.925 0.915 1.23	1.08 1.18 1.1	0.777 0.751 0.731	1.1 1.31 1.11	1.2 1.18 1.06	1.26 1.09 0.992	0.948 0.821 0.838
LMSP03010020	C18DH Sphingomyelin	1.02 0.939 0.821	0.877 0.982 0.939	1.06 0.994 0.828	1.35 1.36 1.24	1.28 1.02 1.1	0.78 0.917 0.8	1.39 1.25 1.15
LMSP03010021	C20DH Sphingomyelin	0.907 0.75 0.786	0.949 1.17 1.13	1.06 0.799 1.1	1.14 0.813 1	1.19 1.02 1.24	0.776 1.01 0.752	1.17 1.42 1.13
LMSP03010022	C22DH Sphingomyelin	1.15 0.884 0.906	0.779 1.1 0.976	1.39 1.31 1.02	1.31 1.15 1.23	1.19 0.977 0.889	0.634 0.9 0.825	1.05 0.945 1
LMSP03010023	C24:1DH Sphingomyelin	1.04 0.903 0.871	0.891 1.1 0.973	1.16 1.04 0.914	1.19 1.25 1.17	1.2 1.03 1.03	0.721 0.834 0.782	1.25 1.04 0.993
LMSP03010024	C24DH Sphingomyelin	0.911 0.756 0.778	0.811 1.05 0.973	1.15 1.05 0.81	1.19 1.31 1.16	1.25 1.07 1.11	0.694 0.814 0.781	1.22 0.959 0.991
LMSP03010025	C26:1DH Sphingomyelin	1.07 0.89 1.22	1.28 0.743 1.33	1.43 0.526 1.42	1.53 0.961 1.3	2.93 1.56 2.08	0.883 0.997 1.06	0.928 1.22 1.4
LMSP03010026	C26DH Sphingomyelin	0.937 1.18 1.05	1 1.03 1.19	1.01 0.63 1.43	1.05 0.653 1.02	1.59 1.15 1.51	1.06 0.922 0.95	1.01 1.02 1.14
LMSP0501AA28	C14DH GlcCer	- - -	- - -	- - -	0.567 0.3 0.767	- - -	2.4 4 2.36	- - -
LMSP0501AA04	C16DH GlcCer	0.817 0.751 1.03	1.55 1.7 2.02	1.03 0.693 1.16	1.2 1.57 0.949	2.06 4.38 0.89	1.98 1.25 1.11	3.9 3.17 1.57
LMSP0501AA29	C18:1DH GlcCer	0.301 0.538 0.376	1.25 0.982 1.2	0.275 1.13 1.06	- - -	1 0.775 1.5	0.221 0.243 0.271	1.26 0.9 1.14
LMSP0501AA19	C18DH GlcCer	- - -	- - -	- - -	- - -	- - -	- - -	- - -
LMSP0501AA20	C20DH GlcCer	- - -	14 10 90	1.75 47.5 62.3	- - -	- - -	0.877 1.46 1.23	- - -
LMSP0501AA21	C22DH GlcCer	0.443 1.05 0.443	2.72 1.11 2.33	0.8 1.64 1.24	2.58 0.579 4.09	7.07 3.24 6.62	3.56 10 12.7	0.892 3.17 2.33
LMSP0501AA22	C24:1DH GlcCer	0.407 0.414 1.64	1.08 1.18 0.863	0.742 0.8 1.05	0.727 0.955 0.621	1.13 0.943 0.863	1.46 1.39 1.57	4.22 3.14 3.59
LMSP0501AA23	C24DH GlcCer	- - -	0.307 0.405 0.071	- - -	0.548 0.571 0.01	0.75 5.74 5.88	- - -	2.88 0.471 0.471
LMSP0501AA24	C26:1DH GlcCer	- - -	- - -	- - -	- - -	- - -	- - -	- - -
LMSP0501AA25	C26DH GlcCer	- - -	- - -	- - -	- - -	- - -	- - -	- - -
LMSP01020001	Sphinganine	1.5 1.23 1	3.32 1.61 0.878	1.6 1.98 1.14	2.55 2.33 1.55	2.38 0.898 1.64	1.38 1.34 0.904	0.933 1.38 1.27
LMSP01050002	Sphinganine-P	1.73 2.37 1.17	1.26 1.57 2.26	3.52 2.29 2.24	1.27 0.467 1.62	1.54 1.11 0.522	4.78 1.59 2.07	1.1 1.13 1.03
LMSP01010001	Sphingosine	1.57 1.65 1.52	1.31 0.838 0.713	0.77 1.01 0.892	1.1 1.13 1	1.07 0.747 1.1	0.634 0.682 0.991	1.2 0.82 1.29
LMSP01050001	Sphingosine-P	1.27 0.982 0.764	0.741 1.64 1.03	1.18 0.764 1.22	1.85 1.53 2.15	1.63 1.41 1.21	0.817 1.23 0.983	0.614 0.825 1.11
LMSP02050002	C16 CerP	1.25 1.12 0.987	1.09 1.09 0.935	1.06 0.96 1.04	0.954 0.923 0.676	1.16 0.981 1.22	1.04 1.13 1.33	0.785 0.731 1.1
LMSP02050003	C16DH CerP	1 1 1	1 1 1	1 1 1	1 1 1	1 2 1	- - -	1.5 1 1
LMSP02050004	C18 CerP	1.12 1.01 1.14	1.03 1.24 1.16	0.745 0.883 0.75	0.883 0.883 0.865	1.5 0.978 1.43	1.08 1.07 0.995	1.25 1.05 0.913
LMSP02050005	C20 CerP	1.88 1.38 1.38	1.14 1.14 1.43	0.727 0.727 0.818	1.5 1 0.875	1.36 0.727 1.18	1 1.38 1.88	3.14 1.57 1.57
LMSP02050006	C22 CerP	5.71 5.71 7.14	1.25 0.675 1	0.75 1 1	- - -	0.667 1 0.667	11 20 40	0.5 1.5 2.5
LMSP02050008	C24 CerP	2.07 1.33 1.4	1.96 2.06 1.45	0.5 0.815 1.76	0.923 0.692 0.615	0.833 0.833 1.25	1.5 1.1 2	0.8 0.8 1.2
LMSP02050007	C24:1 CerP	1.17 1.35 1.05	1.4 1.48 1.52	0.95 0.65 0.933	0.944 0.778 0.815	1 1 1.61	0.8 0.7 1	1.73 0.797 1.08
LMSP02050010	C26 CerP	- - -	- - -	- - -	- - -	- - -	- - -	- - -
LMSP02050011	C26:1 CerP	- - -	- - -	- - -	- - -	- - -	- - -	- - -
-	DNA	1.1 1.09 1.05	1.02 0.957 1.01	1.16 1.17 1.16	1.08 0.984 0.961	0.949 1.01 0.927	1.22 1.08 1.08	0.902 0.895 0.925