Lipidomics studies on macrophages - bone marrow-derived macrophages treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

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Details: 11-HETE Legend: : View detailed data for replicates: View time course graphs Ctrl: Untreated BMDM cells (control) 25-OHC: Cells treated with 25-OH-cholesterol at time 0 *: BMDM cells in lipid-depleted media containing compactin 25-OHC*: cells in lipid-depleted media containing compactin and treated with 25-OHC at time 0 0.2970.203 0.21 0.29 0.163 0.097 0.09 0.03 0.153 0.06 0.013 0.087 0.035 0.012 0.026 0.027 0.018 0.017 0.011 0.005 0.005 0.004 0.115 0.079 0.069 0.069 0.031 0.026 0.024 0.012 0.058 0.04 0.037 0.037 0.027 0.023 0.015 0.013 0.12 0.09 0.08 0.09 0.08 0.07 0.07 0.05 0.12 0.12 0.12 0.08 0.1 0.05 0.05 0.03 0.11 0.11 0.1 0.1 0.1 0.09 0.08 0.05 0.147 0.14 0.086 0.143 0.069 0.056 0.062 0.089 0.121 4.87 3.8 3.96 3.93 3.33 3.44 4.95 0.018 0.031 0.037 0.04 0.031 0.024 0.021 0.018 0.022 0.025 0.047 0.033 0.026 0.02 0.021 0.022 0.051 0.04 0.046 0.033 0.043 0.033 0.033 0.05 0.044 0.04 0.04 0.036 0.046 0.038 0.034 0.046 0.839 0.359 0.127 0.059 0.413 0.345 0.092 0.057 0.024 - - 0.585 0.521 0.51 0.514 0.427 0.273 0.14 0.026 0.405 0.402 0.449 0.387 0.302 0.18 0.102 0.014 0.415 0.295 0.272 0.232 0.164 0.114 0.065 0.01 0.287 0.312 0.369 0.236 0.063 0.699 0.692 1.39 0.24 0.187 0.186 0.169 0.172 0.131 0.1 0.053 0.021 0.271 0.172 0.126 0.112 0.118 0.12 0.111 0.057 0.028 0.405 0.305 0.242 0.181 0.143 0.17 0.143 0.065 0.018 1.36 0.58 0.067 0.337 0.154 1.27 0.812 0.593 0.34 0.385 0.426 0.053 0.09 0.97 0.736 0.961 0.007 0.695 0.27 0.818 0.213 Details Graph Individual Expts Ave Biol. Reps LM_ID Name 25-OHC* * 25-OHC Ctrl 0 hrs 25-OHC* * 25-OHC Ctrl 30 min 25-OHC* * 25-OHC Ctrl 1 hr 25-OHC* * 25-OHC Ctrl 2 hrs 25-OHC* * 25-OHC Ctrl 4 hrs 25-OHC* * 25-OHC Ctrl 8 hrs 25-OHC* * 25-OHC Ctrl 12 hrs 25-OHC* * 25-OHC Ctrl 24 hrs Units . . . . Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ060404) LMFA03060085 11-HETE pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ070710) LMFA03060085 11-HETE pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ070515) LMFA03060085 11-HETE pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG080227) LMFA03060085 11-HETE pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG080325) LMFA03060085 11-HETE pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG080325) LMFA03060085 11-HETE pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD080211) LMFA03060003 11-HETE pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD080311) LMFA03060003 11-HETE pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD080408) LMFA03060003 11-HETE pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG090908) LMFA03060085 11-HETE pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG090908) LMFA03060085 11-HETE pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG090909) LMFA03060085 11-HETE pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG090909) LMFA03060085 11-HETE pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG090909) LMFA03060085 11-HETE pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG090909) LMFA03060085 11-HETE pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) LMFA03060085 11-HETE - 0.1 - 0.09 0.1 0.1 0.1 0.15 0.1 0.09 0.09 0.08 0.14 0.11 0.07 0.07 0.11 0.1 0.11 0.1 0.06 0.06 0.05 0.05 0.05 0.06 0.05 0.05 0.03 0.04 0.05 0.07 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) LMFA03060085 11-HETE - 0.07 - 0.08 0.1 0.09 0.11 0.11 0.09 0.08 0.09 0.07 0.08 0.07 0.08 0.1 0.07 0.07 0.07 0.08 0.06 0.05 0.05 0.07 0.03 0.03 0.05 0.05 0.03 0.02 0.03 0.05 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) LMFA03060085 11-HETE - 0.98 - 0.92 1.13 1.04 1.12 1 1.23 1.06 0.96 0.89 1.11 0.98 1.01 0.86 0.79 0.82 0.85 0.91 0.65 0.67 0.68 0.76 0.49 0.5 0.69 0.75 0.35 0.34 0.51 0.79 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) LMFA03060085 11-HETE - 0.52 - 0.75 0.83 0.8 0.98 1.2 0.83 0.8 0.89 0.81 0.61 0.78 0.98 1.08 0.54 0.46 0.65 0.57 0.6 0.53 0.6 0.73 0.25 0.29 0.54 0.69 0.3 0.19 0.32 0.5 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD110605) 11-HETE pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD110605) 11-HETE pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (ELG050520) LMFA03060085 11-HETE ng/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG060127) LMFA03060085 11-HETE pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG060201) LMFA03060085 11-HETE pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG060210) LMFA03060085 11-HETE pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ070122) LMFA03060085 11-HETE pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ070123) LMFA03060085 11-HETE pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ070124) LMFA03060085 11-HETE pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG070907) LMFA03060085 11-HETE pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG070914) LMFA03060085 11-HETE pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD070716) LMFA03060085 11-HETE pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD070816) LMFA03060085 11-HETE pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD110605) 11-HETE pmol/ml of medium Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD110605) 11-HETE pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD110605) LMFA03060003 11-HETE pmol/ml medium Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120120) LMFA03060085 11-HETE pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120131) LMFA03060085 11-HETE pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120212) LMFA03060085 11-HETE pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120308) LMFA03060085 11-HETE pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (NASH0008) 11-HETE pmol/ml