Lipidomics studies on macrophages - bone marrow-derived macrophages treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

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Details: 7-oxo-cholestenone

Legend:graph_icon: View detailed data for replicatesgraph_icon: View time course graphs
Ctrl:Untreated BMDM cells (control)
25-OHC: Cells treated with 25-OH-cholesterol at time 0
*: BMDM cells in lipid-depleted media containing compactin
25-OHC*: cells in lipid-depleted media containing compactin and treated with 25-OHC at time 0
Details Graph
Individual
Expts		Ave Biol. Reps
LM_ID Name 25-OHC*
*
25-OHC
Ctrl
 0 hrs		 25-OHC*
*
25-OHC
Ctrl
 30 min		 25-OHC*
*
25-OHC
Ctrl
 1 hr		 25-OHC*
*
25-OHC
Ctrl
 2 hrs		 25-OHC*
*
25-OHC
Ctrl
 4 hrs		 25-OHC*
*
25-OHC
Ctrl
 8 hrs		 25-OHC*
*
25-OHC
Ctrl
 12 hrs		 25-OHC*
*
25-OHC
Ctrl
 24 hrs		Units
. . . .
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
 
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
(BCD100322)		LMST01010272 7-oxo-cholestenone -
0.9
-
1.11		 0.83
0.88
1.19
1.42		 0.89
0.56
0.92
1		 1.14
1.26
0.9
0.95		 1.95
1.28
1.85
1.07		 1.14
0.88
1.02
0.76		 0.92
1.19
0.73
0.63		 1
1.34
1.08
0.9		 pmol/ug DNA
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
 
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
(BCD100322)		LMST01010272 7-oxo-cholestenone -
1.19
-
1.21		 1.14
1.04
1.5
0.87		 1.18
0.67
0.99
0.96		 1.18
1
1.06
1.08		 1.8
1.6
1.53
1.36		 1.24
0.92
1.16
1.11		 1.08
1.02
0.93
0.68		 1.18
1.23
1.02
1.01		 pmol/ug DNA
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
 
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
(BCD100322)		LMST01010272 7-oxo-cholestenone -
1.1
-
1.52		 1.3
1.59
2.25
1.33		 1.49
1.07
1.51
1.53		 1.3
1.69
2.28
1.49		 2.04
1.55
3.19
2.05		 1.84
1.47
1.83
2.06		 1.77
2.15
1.86
1.33		 2.2
2.34
2.37
1.96		 pmol/ug DNA
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
 
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
(BCD100322)		LMST01010272 7-oxo-cholestenone -
8.81
-
11.4		 9.38
9.15
13.4
9.47		 10.9
6.62
9.8
11.1		 9.02
11.2
12.9
11.6		 14
10.6
14.4
9.69		 12.4
9.82
13.9
11.5		 9.09
9.87
10
9.45		 11.8
11.5
11
10.1		 pmol/sample
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
 
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
(BCD100322)		LMST01010272 7-oxo-cholestenone -
11.6
-
12.4		 12.9
10.8
16.9
5.8		 14.5
7.92
10.6
10.7		 9.33
8.88
15.2
13.2		 12.9
13.2
11.9
12.3		 13.5
10.3
15.8
16.8		 10.7
8.46
12.8
10.2		 13.9
10.5
10.4
11.3		 pmol/sample
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
 
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
(BCD100322)		LMST01010272 7-oxo-cholestenone -
10.8
-
15.6		 14.7
16.5
25.3
8.87		 18.3
12.7
16.1
17.1		 10.3
15
32.8
18.2		 14.6
12.8
24.7
18.6		 20
16.4
24.9
31.2		 17.5
17.8
25.6
20		 25.9
20
24.1
22		 pmol/sample